Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
03/2004
03/11/2004WO2003009845A9 Substituted urea neuropeptide y y5 receptor antagonists
03/11/2004WO2003000185A3 Complex mixtures exhibiting selective inhibition of cyclooxygenase-2
03/11/2004WO2002083709A3 Kinases and phosphatases
03/11/2004WO2002079441A3 Secreted proteins
03/11/2004WO2002076404A3 Fatty alcohol drug conjugates
03/11/2004US20040049083 Arylpiperazines having activity at the serotonin 1A receptor
03/11/2004US20040049072 RXR modulators with improved pharmacologic profile
03/11/2004US20040049046 Small molecule inhibitors of rotamase enzyme activity
03/11/2004US20040049038 N-substituted with a methylene-bridged nonaromatic ring system, e.g., N-(2-(benzyloxy)-5,6,7,8,9,10-hexahydro-6,9-methanobenzo(a)(8)annulen-11-yl)-N'-(2,2,2-trifluoroethyl)-sulfamide; preventing or treating Alzheimer's Disease
03/11/2004US20040049032 Inhibitors of protein kinases, especially Aurora kinase; anticancer agents
03/11/2004US20040049017 A protein complex which includes a growth factor, growth factor binding protein and vitronectin; for treating cancers, psoriasis, atherosclerosis and wounds prone to hypertrophic scarring
03/11/2004US20040049014 Production of non-immunogenic antibodies having strong affinity for a predetermined antigen
03/11/2004US20040048933 Autonomic nerve regulating agent
03/11/2004US20040048931 Modafinil pharmaceutical compositions
03/11/2004US20040048929 E.g., N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal stabilized with a lipid; improved absorption and penetration; treating ischemia, immune diseases, Alzheimer's disease, osteoporosis, brain disorders, eye diseases, osteoporosis
03/11/2004US20040048927 Pharmaceutical preparation comprising eicosapentaenoic acid and/or stearidonic acid
03/11/2004US20040048924 Ibuprofen composition
03/11/2004US20040048920 2-(p-(1-hydrocarbylsulfonylalkyl)phenyl)-1,1,1,3,3,3-hexafluoro-2-propanol derivatives; treating atherosclerosis, dyslipidemia, diabetes, Alzheimers disease, and Niemann-Pick disease.
03/11/2004US20040048919 Related to premenstrual syndrome, premenstrual dysphoric disorder, perimenopause, menopause, or side effects of hormonal contraceptives; combination of polyunsaturated fatty acid and tocopherol derivative, most of which is not alpha
03/11/2004US20040048912 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
03/11/2004US20040048907 Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
03/11/2004US20040048903 Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes
03/11/2004US20040048901 Increased water solubility and bioabsorption; treatment of CNS disorders such as depression and emesis
03/11/2004US20040048897 Il-8 receptor antagonists
03/11/2004US20040048893 Hydrolysis and decarboxylation of 1-alkyl- or aralkyl-4-((2-hydrocarbyloxycarbonyl-5,6-dimethoxyindan-1-one)-2 -yl)methylpiperidine
03/11/2004US20040048889 Use of non-competitive and selective glur5 antagonists as gultamate receptor modulating compounds
03/11/2004US20040048884 3-aminoalkyluracil derivatives, e.g., 1-(2,6-Difluorobenzyl)-5-(3-methoxyphenyl)-6-methyl-3-(N-methyl-N-(2 -pyridylethyl)-aminoethyl)uracil; contraceptives; treating lupus, sex hormone related cancer, benign prostatic hypertrophy, etc.
03/11/2004US20040048882 4-phenyl-6-alpha-(imidazolyl-, 1,2,4-triazolyl- or pyridyl)-benzyl substituted
03/11/2004US20040048881 Quinazoline derivatives with anti-tumour activity
03/11/2004US20040048872 Sedatives, anticonvulsants, hypnotics and general anesthetics.
03/11/2004US20040048869 Dopamine D4 receptor antagonist with antidepressant or anxiolytic agent.
03/11/2004US20040048867 Especially quinoline carbonyl pyrrolidines with binding selectivity to benzodiazepine site of GABAA receptor to treatanxiety, depression, a sleep disorder, or cognitive impairment.
03/11/2004US20040048862 Chemical compounds
03/11/2004US20040048860 Use of selective noradrenaline reuptake inhibitors for the treatment of tension-type headache
03/11/2004US20040048859 Substituted glutarimides and their use as inhibitors of IL-12 production
03/11/2004US20040048857 Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions.
03/11/2004US20040048856 Monoamine reuptake inhibitors for treatment of CNS disorders
03/11/2004US20040048855 Inhibitors of interleukin 1-beta converting enzyme
03/11/2004US20040048854 From 4-amino-2-methyl-10H-thieno(2,3-b)(1,5) benzodiazpine HCl and 1-methylpiperazine in an aprotic high boiling solvent; purifying in an acid medium; basifying to pH of 7.5-9; and extracting with a low boiling organic solvent
03/11/2004US20040048852 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
03/11/2004US20040048849 Cyclin-dependent kinase (cdk) and glycolene synthase kinase-3 (gsk-3) inhibitors
03/11/2004US20040048848 Novel gamma secretase inhibitors
03/11/2004US20040048843 And aza- and diaza-derivatives thereof; especially treating allergy or nasal congestion
03/11/2004US20040048840 Modulation of matrix metalloproteinase (MMP) activity with aldosterone blocker(s)
03/11/2004US20040048830 Administering a cyclic oligosaccharide such as 6-per-deoxy-6-per-(2,3- dihydroxypropylthio)- gamma -cyclodextrin; treating depression and other psychological disorders such as Cushing's syndrome, schizophrenia and severe anxiety
03/11/2004US20040048828 Immunosuppressive agent and food
03/11/2004US20040048827 Regulation of the expression of genes as beta -secretase, presenilin-1, presenilin-2 gamma -amyloid protein precursor.
03/11/2004US20040048820 Prevention or therapy of cardiovascular complications
03/11/2004US20040048801 Use of activity-dependent neurotrophic factor-derived polypeptides for enhancing learning and memory:pre-and post-natal administration
03/11/2004US20040048795 Stimulating a vagus nerve pathway in the brain; inhibiting apoptosis of a cardiac myocyte
03/11/2004US20040048373 Production and long-term in vitro culture of these cell populations, and the use of neuroblasts in the treatment of various neuronal disorders as well as the identification of compositions which affect neuroblasts
03/11/2004US20040048372 Extracting and recovering embryonic-like stem cells, including pluripotent or multipotent stem cells, from an exsanguinated human placenta; use of the isolated and perfused placenta as a bioreactor in which to propagate endogenous/exogenous cells
03/11/2004US20040048338 IL-17 receptor like molecules and uses thereof
03/11/2004US20040048294 Diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins
03/11/2004US20040048266 Regulation of human membrane-type serine protease
03/11/2004US20040048263 Novel g protein-coupled receptor protein and dna thereof
03/11/2004US20040048256 Isolated polypeptide of given sequence; use in screening for identifying therapeutic antibodies and drugs
03/11/2004US20040048245 Isolated polypeptide of given sequence; identifying modulators by contacting with compound and detecting binding activity; use in diagnosis and treatment
03/11/2004US20040047907 Controlled release hydrocodone formulations
03/11/2004US20040047851 Treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase activity which comprises administering to the subject an amount of a zinc sphingomyelinase inhibitors effective to decrease
03/11/2004US20040047807 Neurotoxic substances, which have a toxic effect in particular for the axon and the nociceptive nerve endings, for the preparation of an agent for the treatment of joint pain.
03/11/2004DE10240343A1 Peroxynitrit-Umlagerungskatalysatoren Peroxynitrite rearrangement catalysts
03/11/2004DE10240035A1 Biogene Polyester-Partikel definierter Größe mit funktionalisierten Oberflächen:Herstellungsverfahren und pharmazeutische Zubereitungen, in denen diese enthalten sind Biogenic polyester particles of defined size with functionalized surfaces: Method and pharmaceutical preparations in which they are contained
03/11/2004DE10238723A1 Phenyl-substituierte Pyrazolyprimidine Phenyl-substituted Pyrazolyprimidine
03/11/2004DE10238722A1 Improving attention, concentration, cognition, learning and/or memory performance, using selective phosphodiesterase 9A inhibitors, preferably 4H-pyrazolo-(3,4-d)-pyrimidin-4-one derivatives
03/11/2004CA2497255A1 Method for producing biodegradable, functionalised polymer particles, and use of the same as medicament carriers
03/11/2004CA2497161A1 Herbal extract comprising a mixture of saponins obtained from sapindus trifoliatus for anticonvulsant activity
03/11/2004CA2496920A1 Adenosine a2a receptor antagonists for treating restless legs syndrome or related disorders
03/11/2004CA2496798A1 Embossable and writable multilaminate backing construction
03/11/2004CA2496695A1 New therapeutic uses of (4-(2-fluorophenyl)-6-methyl-2­(1-piperazinyl)thieno{2,3-d}pyrimidine
03/11/2004CA2495914A1 N-biarylmethyl aminocycloalkanecarboxamide derivatives
03/11/2004CA2495853A1 2,5-dioxoimidazolidin-4-yl acetamides and analogues as inhibitors of metalloproteinase mmp12
03/11/2004CA2495248A1 Anabaseine derivatives useful in the treatment of neurodegenerative diseases
03/11/2004CA2493199A1 Peroxynitrite rearrangement catalysts used for the treatment or prophylaxis of diseases caused by peroxynitrite-mediated reactions
03/10/2004EP1396493A1 Heterocyclic compounds
03/10/2004EP1396492A1 Prodrug of an ice inhibitor
03/10/2004EP1396488A1 Fused heterocyclic compound and medicinal use thereof
03/10/2004EP1396271A1 Use of germination-activated ganoderma lucidium spores as anti-aging agent and against menopause symptoms
03/10/2004EP1395684A2 New polynucleotides and polypeptides of the ifnalpha-7 gene
03/10/2004EP1395652A2 Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same
03/10/2004EP1395605A2 Polymeric immunoglobulin fusion proteins that target low-affinity fcgamma receptors
03/10/2004EP1395602A2 Novel human potassium channel beta subunit
03/10/2004EP1395591A1 Corticotropin releasing factor antagonists
03/10/2004EP1395586A2 Method for the production of zolpidem
03/10/2004EP1395583A1 New phenylpiperazines
03/10/2004EP1395582A1 Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same
03/10/2004EP1395578A1 Carbazole derivatives and their use for the preparation of pharmaceutical compositions for the treatment of npy related diseases
03/10/2004EP1395576A1 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395575A1 4-(penyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395574A1 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395568A1 4-aminopyrimidine derivatives
03/10/2004EP1395567A1 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
03/10/2004EP1395566A1 Tricyclic compounds useful as angiotensin ii agonists
03/10/2004EP1395561A1 Carbamate and oxamide compounds as inhibitors of cytokine production
03/10/2004EP1395560A1 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivativ es for the treatment of epilepsy and other neurological disorders
03/10/2004EP1395559A1 4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain anxiety or gastrointestinal disorders
03/10/2004EP1395558A1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395557A1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395556A1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
03/10/2004EP1395555A1 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders