Patents for A61P 19 - Drugs for skeletal disorders (81,981)
02/1993
02/24/1993EP0528586A1 Inhibiting osteoclast-mediated bone resorption using aminoalkyl-substituted phenyl derivatives
02/23/1993US5189212 Used in estrogen replacement therapy like menopause, osteoporosis therapy, prevention of excessive hair growth of body and infertility
02/16/1993CA1313622C Pharmaceutical composition containing 17.beta.oestradiol and desogestr el
02/10/1993CA2088518A1 Method of inhibiting osteoclast-mediated bone resorption by administration of aminoalkyl-substituted phenyl derivatives
02/10/1993CA2075612A1 Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives
02/03/1993EP0525420A1 Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors
02/02/1993US5183814 Selective oestrogen therapy for perimenopausal or postmenopausal conditions
01/1993
01/27/1993EP0524633A2 Pharmaceutical composition suitable for influencing the reticuloendothelial system
01/20/1993EP0359739B1 Tranforming growth factor-beta
01/13/1993EP0522576A2 Aminoethane-1,1-bisphosphonic acids and aminoethane-1,1-alkylphospinic/phosphonic acids, process of their preparation and their use
01/13/1993EP0522080A1 High level expression of basic fibroblast growth factor having a homogeneous n-terminus
01/12/1993US5179110 Adrenergic stimulants; antiulcer agents, bronchodilators, treatment of diarrhea, glaucoma, osteoporisis, prostate, diabetes, migraine
01/09/1993WO1993000921A1 Remedy for osteoporosis
01/09/1993CA2090453A1 Remedy for osteoporosis
01/07/1993WO1993000432A1 Bmp-9 compositions
01/07/1993WO1993000348A1 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
01/07/1993WO1993000050A1 Pharmaceutical formulations of osteogenic proteins
01/07/1993DE4120990A1 Verfahren zur herstellung von diacetylrhein Process for the preparation of diacetylrhein
01/07/1993CA2112250A1 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
01/02/1993CA2072834A1 Ketone derivatives
12/1992
12/30/1992EP0520573A1 Cyclic imide derivatives
12/30/1992EP0520427A1 Cyclopropenone derivatives
12/30/1992EP0520414A1 Process for the preparation of diacetylrhein
12/30/1992CN1067427A Pyrazolopyridine compound and processes for preparation thereof
12/28/1992CA2072551A1 Cyclic imide derivatives
12/26/1992WO1993000322A1 Method of preparing diacetyl rhein
12/23/1992WO1992022294A1 Immunomodulatory azaspiranes
12/23/1992CA2110577A1 Immunomodulatory azaspiranes
12/15/1992CA1311483C 5-pyrazolylcarbonyl- and 5-pyrazolyvinyl-phenoxy acetic acid derivatives and processes for preparing the same
12/10/1992WO1992021379A1 Radiolabeled metal-binding protein for the treatment of arthritis
12/10/1992WO1992021365A1 Therapeutic compositions for osteoinduction
12/10/1992WO1992021354A1 Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
12/10/1992WO1992019617A3 Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
12/09/1992EP0516941A1 Pyrazolopyridine compounds and processes for preparation thereof
12/06/1992WO1992021369A1 Synthetic calcitonin peptides
12/06/1992CA2088922A1 Synthetic calcitonin peptides
12/02/1992EP0516069A1 Leukotriene B4 antagonist
12/01/1992CA2069667A1 Leukotriene b4 antagonist
11/1992
11/26/1992WO1992020371A1 Targeted delivery of bone growth factors
11/26/1992WO1992017446A3 Pyridazinone acetic acids aldose reductase inhibitors
11/25/1992EP0515228A2 Essential pure human parathyroid hormone
11/25/1992EP0514720A2 Bone growth factors and inhibitors of bone resorption for promoting bone formation
11/19/1992EP0514130A2 Bone acidic glycoprotein (BAG-75) for inhibiting bone resorption
11/19/1992EP0513387A1 Active oxygen inhibitor
11/19/1992EP0513334A1 USE OF A BONE MORPHOGENETIC PROTEIN IN SYNERGISTIC COMBINATION WITH TGF-$g(b) FOR BONE REPAIR
11/17/1992US5164368 Treatment for osteoporosis using growth hormone releasing factor (grf) in combination with parathyroid hormone (pth)
11/14/1992CA2068389A1 Method for inhibiting bone resorption
11/12/1992WO1992019735A1 GLYCAM-1 (Sgp 50), A SELECTIN LIGAND
11/12/1992WO1992019617A2 Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
11/12/1992WO1992019262A1 Bone growth factors and inhibitors of bone resorption for promoting bone formation
11/12/1992WO1992017426A3 7-chromanyl esters of phenols and benzoic acids having retinoid-like activity
11/12/1992CA2108029A1 Glycam-1(sgp 50), a selectin ligand
11/11/1992EP0512844A1 Targeted delivery of bone growth factors
11/11/1992EP0512400A1 Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
11/11/1992CA2102808A1 Targeted delivery of bone growth factors
11/05/1992WO1992019628A1 Medicaments containing azacyclodiphosphonic acid derivatives, novel azacyclodiphosphonic acid derivatives and process for producing them
11/05/1992DE4114586A1 Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung Medicines containing azacyclodiphosphonsaeurederivate new azacyclodiphosphonsaeurederivate and procedures for their production
11/05/1992CA2109318A1 Medicaments containing azacyclodiphosphonic acid derivatives, new azacyclodiphosphonic acid derivatives, as well as processes for their preparation
10/1992
10/29/1992WO1992018150A1 Mhc conjugates useful in ameliorating autoimmunity
10/29/1992WO1992008985A3 Ligand-mediated immunofunctional hormone binding protein assay method
10/21/1992EP0509317A2 Use of droloxifene in the treatment of bone diseases
10/15/1992WO1992017482A1 Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof
10/15/1992CA2107892A1 Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof
10/14/1992CN1065269A Pyridazinone acetic acids
10/06/1992US5153308 S-sulfonated calcitonin derivatives
10/01/1992WO1992016553A1 Monoclonal and chimeric antibodies specific for human tumor necrosis factor
10/01/1992WO1992016496A1 N-[[4,5-dihydroxy- and 4,5,8-trihydroxy-9,10-dihydro-9,10-dioxo-2-anthracene-yl]carbonyl]amino acids useful in the therapy of osteoarticular affections
09/1992
09/30/1992CN1064813A Methods and compositions for treatment and repair of defects or lesions in cartilage
09/29/1992WO1992017446A2 Pyridazinone acetic acids aldose reductase inhibitors
09/29/1992US5151274 Calcium and trace mineral supplements
09/29/1992CA2107104A1 Pyridazinone acetic acids as aldose reductase inhibitors
09/27/1992WO1992017426A2 7-chromanyl esters of phenols and benzoic acids having retinoid-like activity
09/27/1992CA2105158A1 7-chromanyl esters of phenols and benzoic acids having retinoid-like activity
09/23/1992EP0505058A1 Thienopyridine derivatives and pharmaceutical compositions containing them
09/23/1992EP0504799A1 Mixted pyridine-2,4- and 2,5-dicarboxylic acid diamides, process for their preparation, their use as well as medicaments based on these compounds
09/19/1992CA2736076A1 Monoclonal and chimeric antibodies specific for human tumor necrosis factor
09/19/1992CA2063177A1 Mixed pyridine-2,4- and -2,5-dicarboxamides, a process for preparing them, the use thereof and pharmaceuticals based on these compounds
09/17/1992WO1992015615A1 Serum calcium depressing factor
09/17/1992WO1992015323A1 Protein-induced morphogenesis
09/17/1992WO1992015292A1 Therapeutic compositions to protect and resuscitate mammalian cells and methods for preparing and using same
09/16/1992EP0503648A1 CD2-Binding domain of lymphocyte function associated antigen 3
09/13/1992WO1992016622A1 Cd2-binding domain of lymphocyte function associated antigen 3
09/03/1992WO1992014462A1 Cytokine inhibitors
09/01/1992US5143829 One of the alanine residues following N-terminal methionine is removed
08/1992
08/27/1992WO1992014474A1 Methods for the treatment of osteoporosis
08/20/1992WO1992013864A1 Acylamino-alkyliden-hydroxy-bisphosphonic acids useful in the therapy of osteoarticular diseases
08/20/1992WO1992013565A1 Growth factor containing matrix for the treatment of cartilage lesions
08/19/1992CN1063685A Calcium uptake inhibitors
08/14/1992WO1992014725A1 Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity
08/14/1992CA2101160A1 Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity
08/12/1992EP0498665A1 Hydroxamic acids derivatives, process for their preparation and use thereof
08/11/1992US5137887 Salts of optically active 4-hydroxy-8(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo(1,5-a)-1,3,5- triazines and a process for production thereof
08/08/1992WO1992013831A1 Hydroxamic acid derivatives, process for their preparation and use thereof
08/08/1992CA2100661A1 Hydroxamic acid derivatives, process for their preparation and use thereof
08/06/1992WO1992013095A1 Methods for treating tumor necrosis factor mediated diseases
08/05/1992CN1017708B Method for preparation of pyrazolotriazine compounds
07/1992
07/29/1992EP0496520A1 Novel bone acting agents
07/28/1992US5134159 Skin disorders
07/28/1992US5133956 Radiolabeled metal-binding protein for the treatment of arthritis
07/23/1992CA2059421A1 Bone acting agents