Patents for A61P 11 - Drugs for disorders of the respiratory system (87,767)
05/1999
05/26/1999EP0918059A1 Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them
05/26/1999EP0917462A1 Cell adhesion inhibitors
05/26/1999CN1217714A Substituted indazole derivatives and their use as inhibitors phosphodiesterase (PDE) type IV and production of tumor necrosis factor (TNF)
05/26/1999CN1217654A Process for production of powdered pulmoney surfactant preparations
05/25/1999US5907043 Coupling n-(4-methoxybenzoyl)-l-valyl-l-proline or a salt with 3-amino-4-methyl-1,1,1-trifluoro-2-pentanol forming (s)-1-(s)-2-(4-methoxybenzamido)-3-(2,2,2-trifluoro-1-hydroxy ethyl)propyl)pyrrolidine-2-carboxamide, oxidizing the product
05/20/1999WO1999024433A1 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
05/20/1999WO1999024423A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999WO1999024408A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/20/1999WO1999024404A1 Substituted pyridine compounds as anti-inflammatory agents
05/20/1999WO1999024399A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999WO1999024398A2 Urea derivatives and their use as integrin inhibitors
05/20/1999WO1999024069A1 Preventives and remedies for diffuse lung diseases
05/20/1999WO1999024039A1 Method for reducing mast cell mediated allergic reactions
05/20/1999WO1999024035A1 Benzothiazole protein tyrosine kinase inhibitors
05/20/1999WO1999024024A2 Treatment of t-helper cell type 2 mediated immune diseases with retinoid antagonists
05/20/1999WO1999015553A3 Costimulating t-cell polypeptide, monoclonal antibodies, their preparation and use
05/20/1999DE19750529A1 New heterocyclic alpha-hydroxycarboxylic acid derivatives useful for treating hypertension, chronic coronary insufficiency, asthma, prostate cancer etc.
05/20/1999CA2309598A1 Preventives and remedies for diffuse lung disease
05/20/1999CA2309319A1 Benzothiazole protein tyrosine kinase inhibitors
05/20/1999CA2309162A1 Piperidine derivatives and their use as tachykinin antagonists
05/20/1999CA2308716A1 Urea derivatives and their use as integrin inhibitors
05/20/1999CA2308406A1 Method for reducing mast cell mediated allergic reactions
05/20/1999CA2308359A1 Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
05/20/1999CA2308358A1 Heterocyclic compounds having mmp and tnf inhibitory activity
05/19/1999EP0916729A2 Novel reductase
05/19/1999EP0916727A2 Novel LysS
05/19/1999EP0916673A1 6-Amino purine derivatives having PDE-IV inhibition activity
05/19/1999EP0916672A1 6-Amino purine derivatives having PDE-IV inhibition activity and intermediates
05/19/1999EP0915908A1 Dolastatin pentapeptide derivatives and their use as antitumor agents
05/19/1999EP0915704A1 Use of phosphinyloxyalkyl and phosphonamidoalkyl derivatives of cyclopentane(ene) as therapeutic agents
05/19/1999EP0915698A1 Therapeutic treatment for vegf related diseases
05/19/1999EP0915651A1 Il-8 receptor antagonists
05/19/1999EP0752986B1 N-heterocyclyl sulphonamide derivatives and their use as endothelin antagonists
05/19/1999CN1217025A Processed polypeptides with IL-16 activity, process for preparing same and their use
05/19/1999CN1217022A Therapeutic uses of keratinocyte growth factor
05/19/1999CN1216993A Alkyl-4-silyl-phenols and esters thereof as anti-atherosclerotic agent
05/19/1999CN1216980A Triaryl compounds
05/19/1999CN1216921A Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2,6-di-alkyl-4-silyl-phenols
05/19/1999CN1216767A Novel 5-membered ring heterocycles, their prepn. their use and pharmaceutical preparations comprising them
05/19/1999CN1216762A 2-(arylphenyl) amino-imidazoline derivatives
05/19/1999CN1216710A Liniment made of traditional Chinese medicine for treating pharyngitis, and prepn. method therefor
05/19/1999CN1043405C Method for prepn. of pharmaceutical compositions contg. heterocyclic amide derivatives
05/18/1999US5905156 Potassium channel activators and bronchodilators
05/18/1999CA2179264C 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
05/18/1999CA2158952C 2-substituted morpholine and thiomorpholine derivatives as gaba-b antagonists
05/14/1999WO1999023097A1 Substituted porphyrins
05/14/1999WO1999023077A1 Indazole bioisostere replacement of catechol in therapeutically active compounds
05/14/1999WO1999023076A1 Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
05/14/1999WO1999023063A1 Substituted anilides
05/14/1999WO1999007351A3 Indole derivatives and their use as mcp-1 antagonists
05/14/1999WO1999001467A3 Therapeutically active compounds with low systemic activity due to reduce half life
05/14/1999WO1998051289A3 Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
05/14/1999CA2309175A1 Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
05/14/1999CA2309150A1 Indazole bioisostere replacement of catechol in therapeutically active compounds
05/12/1999EP0915086A1 Phenylsulfonamide derivatives
05/12/1999EP0914605A1 Molecular model for vla-4 inhibitors
05/12/1999EP0914432A2 Secreted proteins and polynucleotides encoding them
05/12/1999EP0914417A2 Human dnase ii
05/12/1999EP0914345A1 Antibodies binding to monocyte chemoattractant protein 1 (mcp-1) receptor (ccr2)
05/12/1999EP0914322A1 New indolyl and benzofuranyl carboxamides as inhibitors of nitric oxide production
05/12/1999EP0914319A1 Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists
05/12/1999EP0914102A1 Compositions and methods for treating or preventing diseases of body passageways
05/12/1999EP0735888A4 Purine compositions and methods for administration
05/12/1999CN1216531A Indole derivatives useful as endothelin receptor antagonists
05/11/1999US5902567 Administering to lung by inhalation physiologically acceptable salt to hydrate secretions, concurrently administering uridine triphosphate or derivative to stimulate secretion, collecting expectorated mucus sample
05/06/1999WO1999022243A1 148 human secreted proteins
05/06/1999WO1999021834A1 Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
05/06/1999WO1999021831A1 Tricyclic compounds as cgmp-pde inhibitors
05/06/1999WO1999021830A1 Process for stereoselective synthesis of prostacyclin derivatives
05/06/1999WO1999021559A1 MORPHOLINO-N-ETHYL ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS
05/06/1999WO1999021553A1 Antagonists of gonadotropin releasing hormone
05/06/1999WO1999021546A1 N,N-DIETHYLGLYCOLAMIDO ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS
05/06/1999WO1999015493A8 9,10-dihydro-9,10-ethanoanthracene derivatives as phospholipase inhibitors
05/06/1999WO1999013054A3 Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues
05/06/1999EP0913481A2 Staphylococcus aureus member of the DEAD-type ATP-dependent RNA helicases (dbpB)
05/06/1999EP0913477A2 LacC gene encoding a tagatose-6-phosphate kinase
05/06/1999EP0913476A2 Ornithine carbamoyl transferase sequence and uses thereof
05/06/1999EP0913156A1 Methods for treating hypercoagulable states or acquired protein C deficiency
05/06/1999EP0912747A1 Aspartic protease
05/06/1999EP0912740A1 Rantes homolog from prostate
05/06/1999EP0912608A2 Choline binding proteins for anti-pneumococcal vaccines
05/06/1999EP0912575A1 Improved methods for the synthesis of chemical compounds having pde-iv inhibitory activity
05/06/1999EP0912568A1 Novel imidazopyridines
05/06/1999EP0912558A1 Substituted indazole derivatives and their use as phosphodiesterase (pde) type iv and tumor necrosis factor (tnf) inhibitors
05/06/1999EP0912521A1 Substituted indazole derivatives and their use as inhibitors phosphodiesterase (pde) type iv and the production of tumor necrosis factor (tnf)
05/06/1999EP0912518A1 Substituted pyridines as selective cyclooxygenase-2 inhibitors
05/06/1999EP0912505A1 Il-8 receptor antagonists
05/06/1999EP0912184A1 Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
05/06/1999EP0912178A1 Methods of treating hypertension
05/06/1999EP0912091A1 Use of gaba uptake inhibitors as anti-tussive agents
05/06/1999CA2847985A1 Process for stereoselective synthesis of prostacyclin derivatives
05/06/1999CA2309135A1 N,n-diethylglycolamido ester prodrugs of indole spla2 inhibitors
05/06/1999CA2308454A1 Antagonists of gonadotropin releasing hormone
05/06/1999CA2308443A1 Morpholino-n-ethyl ester prodrugs of indole spla2 inhibitors
05/06/1999CA2307320A1 148 human secreted proteins
05/06/1999CA2307163A1 Process for stereoselective synthesis of prostacyclin derivatives
05/05/1999CN1216043A Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors
05/04/1999US5900434 Method for inhibiting the production of interleukin-1 or tumor necrosis factor-α by administering acanthoic acid
05/04/1999US5900421 Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
05/04/1999US5900257 Cosmetic/pharmaceutical compositions comprising lanthanide manganese, tin and/or yttrium salts as substance P antagonists