Patents
Patents for A61K 51 - Preparations containing radioactive substances for use in therapy or testing in vivo (24,291)
03/1989
03/08/1989EP0306168A1 Preparation of radiolabeled conjugates
03/07/1989US4810486 From sulfonate-containing bis-phosphonic acid, reducing agent, pertechneatate ions
03/01/1989EP0305320A2 Multinucleic substituted complexants, complexes and complex salts, process for their preparation and pharmaceutical agents containing them
03/01/1989EP0304780A1 Process for labelling substances with technetium or rhenium
02/1989
02/23/1989WO1989001629A1 Human ovarian tumor-associated antigen specific for monoclonal antibody ov-tl3
02/23/1989WO1989001342A2 Diagnostic or radiotherapeutic composition comprising a hydrogen containing compound
02/23/1989WO1989001340A1 Method for treating malignancy and autoimmune disorders in humans
02/21/1989US4806628 Specific binding; diagnosis and treatment of melanomas
02/14/1989US4804529 Use of specific relaxation agents for organs or pathologies for modifying the contrasts in medical imaging by nuclear magnetic resonance
02/14/1989CA1249998A1 Metal-isonitrile adducts for preparing radionuclide complexes for labelling and imaging agents
02/01/1989CN1030748A Vinyl substituted radiohalogen conjugates for protein labeling
01/1989
01/31/1989CA1249514A1 Stable stannous chloride composition for labeling with radioactive technetium
01/31/1989CA1249513A1 Radiolabelled lipoproteins and method for making same
01/26/1989WO1989000692A1 Second generation monoclonal antibodies having binding specificity to tag-72 and human carcinomas and methods for employing the same
01/26/1989WO1989000583A1 Improved immunotoxin therapies utilizing purified ricin a-chain species
01/26/1989WO1989000557A1 Aminopolycarboxylic acids and derivatives thereof
01/25/1989EP0300969A2 Polyethylene glycol carbaminates
01/25/1989EP0300431A2 Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides
01/25/1989EP0300341A2 Benzodiazepine derivatives, their radiolabelled derivatives and use of the latter in immunoassays for detecting benzodiazepines
01/25/1989CN1030588A Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation
01/18/1989EP0299795A2 Aminopolycarboxylic acids and derivatives thereof
01/18/1989EP0299354A2 Monoclonal antibodies against protein E7 of the human papilloma virus type 16, their production process and their use
01/17/1989US4798719 Method for selection of antigens suitable as in vivo targets for antibodies
01/12/1989WO1989000062A1 Radiotherapy
01/12/1989WO1989000051A1 Fibrin-binding compound and method
01/11/1989EP0298436A2 Use of a vehicle with a high tumour affinity
01/10/1989USRE32826 Target seeking ligands
01/10/1989CA1248551A1 Radioactive iodine labeled phenolic amines
01/10/1989CA1248474A1 Method for labeling phagocytic cells
01/03/1989US4795627 Tritium labelled N-mustard type compounds and a process for their production
01/03/1989US4795626 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
01/03/1989CA1248090A1 Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
12/1988
12/28/1988EP0297066A1 Novel fibrinolytic enzymes
12/28/1988EP0296522A2 Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation
12/27/1988US4794187 35 S-labelled 1.4-dihydropyridines
12/27/1988US4794178 Carrier-free
12/27/1988US4793987 Amino acid or nucleotide with carboxyl- or sulfonate substituted pyridine stabilizer
12/15/1988WO1988009823A1 Amine derivatives of anthracycline antibiotics and antibody conjugates thereof
12/15/1988WO1988009797A1 Autocrine motility factors in cancer diagnosis and management
12/07/1988EP0294294A2 Amine derivatives of anthracycline antibiotics
12/06/1988US4789736 Complexes of technetium-99m with propylene amine oximes
12/06/1988US4789543 Neutral technetium 99-m complexes useful as radiodiagnostic agents
12/06/1988US4789542 Medical diagnosis
12/06/1988US4789541 Preadministering pill containing stannous chloride and potassium perchlorate
12/06/1988US4789501 Yttria, silica, and alumina; radiation therapy of cancer
12/06/1988CA1245980A1 Physiologic chemical method of labeling protein substances with the radionuclides of indium
12/01/1988WO1988009182A1 Hepatic blocking agents
12/01/1988WO1988009152A1 Apparatus providing diagnosis and selective tissue necrosis
12/01/1988WO1988007986A3 Compounds useful particularly for radiotherapy or imaging of cancer
11/1988
11/30/1988EP0292689A2 Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs
11/29/1988CA1245553A1 Contrast agents for nmr imaging
11/23/1988EP0292291A2 Linear and cyclic analogs of alpha-msh fragments with extraordinary potency
11/23/1988EP0291605A2 Bone marrow suppressing agents
11/23/1988EP0166755B1 Diagnostic and contrast agent
11/17/1988WO1988008854A1 Monoclonal antibodies to renal cell carcinoma
11/17/1988WO1988008720A1 Preparation of tc-99m radiopharmaceuticals
11/17/1988WO1988007382A3 Method for labelling antibodies with a metal ion
11/17/1988EP0291281A1 Preparation of Tc-99m Radiopharmaceuticals
11/15/1988US4784958 Cardiovascular disorders
11/15/1988US4784481 Transmitted and/or incident light microscope
11/15/1988US4784116 Capsule for interstitial implants
11/15/1988CA1244760A1 Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
11/09/1988EP0290041A2 Radioactive metal chelates of dipyridoxyl phosphate
11/08/1988US4783330 Monoclonal antibodies to activated platelets
11/08/1988CA1244344A1 Tumor localization and therapy with labeled antibodies and antibody fragments specific to tumor- associated markers
11/03/1988WO1988008422A1 Substituted cyclic complex-forming substances, complexes and complex salts, process for manufacturing same, and pharmaceutical agents which contain them
11/02/1988EP0289187A2 Vinyl substituted radiohalogen conjugates for protein labeling
11/02/1988EP0288558A1 Detection of vascular disease
11/01/1988USH545 In vivo generator for radioimmunotherapy
11/01/1988US4782231 Standard component 99m Tc elution generator and method
11/01/1988US4781912 Radiodiagnosis
10/1988
10/26/1988EP0287909A1 Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor
10/26/1988CN88102139A Process for preparing ligands nitrogenous cycle
10/25/1988US4780412 Isolation from epithelial cell cultures
10/25/1988CA1243784A1 Radionuclide metallic vapour
10/25/1988CA1243603A1 Phosphonic acid complexes for the treatment of calcific tumors
10/20/1988WO1988008135A1 Human monoclonal antibodies binding determinants of gram negative bacteria
10/20/1988WO1988007986A2 Compounds useful particularly for radiotherapy or imaging of cancer
10/20/1988DE3710730A1 Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel Substituted complexing agents, complexes and complex salts thereof, processes for their preparation and pharmaceutical compositions containing them
10/19/1988EP0287465A1 Cyclic ligands containing nitrogen, metal complexes formed by these ligands, diagnostic compositions containing them and process for their preparation
10/18/1988US4778672 Method of isolating radioactive perrhenate or pertechnetate from an aqueous solution
10/18/1988CA1243329A1 Complexes of technetium-99m with propylene amine oximes
10/11/1988US4777169 Radioimmunoassay
10/06/1988WO1988007521A1 Substituted complex-forming substances, complexes and complex salts, process for manufacture thereof and pharmaceutical agents which contain them
10/06/1988WO1988007382A2 Method for labelling antibodies with a metal ion
10/04/1988US4775759 Synthesis and utilization of 17-methyl and 17-cyclopropylmethyl-3,14-dihydroxy-4,5α-epoxy 6β-fluoromorphinans (foxy and cyclofoxy) as (18F)-labeled opioid ligands for position emission transaxial tomography (PETT)
10/04/1988US4775638 Single vial technique for radiolabeling protein
10/04/1988CA1242696C Intermediates for the preparation of radioactive steroids
10/04/1988CA1242695C Intermediates for the preparation of radioactive estradiene derivatives
09/1988
09/28/1988EP0284071A2 Metal-radionuclide-labeled proteins and glycoproteins for diagnosis and therapy
09/28/1988CN88102026A Chemo-radio-immuno-conjugates
09/20/1988US4772548 Radioisotopicassay using isotope transfer to chelator-target recognition molecule conjugate
09/14/1988EP0282057A2 Chemo-radio-immuno-conjugates
09/07/1988WO1988006451A1 Immunosuppression in immunotoxin based human therapy
08/1988
08/31/1988EP0280209A2 Monoclonal antibodies against melanoma-associated antigens, hybrid cell lines producing these antibodies, and use therefor
08/31/1988EP0280135A2 Protein C-inhibitor (PCI) as a pharmaceutical and diagnostic agent, process for the preparation of such a pharmaceutical or diagnostic agent and a composition containing PCI
08/30/1988US4767843 Monoclonal antibody to cardiac myosin heavy chain
08/30/1988US4767609 Therapeutic and diagnostic processes using isotope transfer to chelator-target recognition molecule conjugate
08/24/1988EP0279417A2 Ester-substituted diaminedithiols and radiolabeled complexes thereof
08/23/1988US4765971 Reaction of technetium compound with enzene or substituted benzene in the presence of reducing agent and metal halide