Patents
Patents for A61K 51 - Preparations containing radioactive substances for use in therapy or testing in vivo (24,291)
03/1993
03/24/1993EP0532718A1 ?99m Tc LABELED LIPOSOMES
03/24/1993EP0532566A1 ?99m Tc CYCLOPENTADIENYL CARBONYL COMPLEXES, METHOD OF PREPARING THEM, AND THEIR USE IN MEDICAL DIAGNOSIS.
03/23/1993US5196577 Radioactive
03/23/1993US5196576 Chelating compounds and their use
03/23/1993US5196515 Thiolactone bifunctional chelating agents for diagnostic and therapeutic products
03/23/1993US5196510 Polypeptides
03/23/1993US5196404 Inhibitors of thrombin
03/18/1993WO1993004702A1 Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
03/18/1993WO1993002652A3 Modified haptens useful as imaging and therapeutic agents
03/17/1993EP0531472A1 Humanized and chimeric monoclonal antibodies
03/16/1993US5194594 Conjugation With Heterobifunctional Reagent, Radionucleotide Label
03/16/1993US5194581 Biodegradable poly(phosphoesters)
03/16/1993US5194425 Mhc-mediated toxic conjugates useful in ameliorating autoimmunity
03/16/1993CA1314503C Detectable molecules, method of preparation and use
03/13/1993CA2309400A1 Intravascular system with inflatable member and member mounted thereon
03/10/1993EP0417191B1 Formulation for antibody reagents
03/10/1993EP0406363B1 Method to diagnose amyloidoses specifically and substance therefor
03/09/1993US5192526 Kit for preparation of rhenium therapeutic agents for bone cancer without purification
03/09/1993US5192525 High affinity tamoxifen derivatives and uses thereof
03/09/1993CA1314209C Composition and method for use for liposome encapsulated compounds for neutron capture tumor therapy
03/04/1993WO1993004194A1 LABELLED β-AMYLOID PEPTIDE AND ALZHEIMER'S DISEASE DETECTION
03/04/1993WO1993003772A1 Imaging of infections
03/03/1993EP0529645A1 Process for the preparation of backbone polysubstituted chelates.
03/03/1993EP0529031A1 Improved inhibitors of thrombin
03/03/1993EP0528891A1 Method for increasing blood-brain barrier permeability
03/02/1993US5190742 Device and method for carrying out a plurality of sequential transformations of a substrate
03/02/1993US5190741 Aminopropyl Radioactive Iodobenzamides
02/1993
02/25/1993DE4128181A1 New complexes of radioactive technetium - with aldoxime-substd. poly:ol or sugar deriv., useful for imaging the heart, brain and kidneys and for diagnosis of tumours
02/24/1993EP0528663A2 Monoclonal antibody to a synaptophysin
02/24/1993EP0528007A1 NUCLEOTIDIC SEQUENCES CODING FOR VARIABLE REGIONS OF $g(b) CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDIC SEGMENTS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
02/24/1993EP0527954A1 Molecular recognition units
02/24/1993EP0527755A1 Improved method for radiolabeling monovalent antibody fragments
02/24/1993EP0510132A4 Polymeric carriers for release of covalently linked agents
02/24/1993CN1069339A Electrolytic cell and process for labeling of proteins and peptides
02/23/1993US5188816 Using polyazamacrocyclic compounds for intracellular measurement of metal ions using MRS
02/18/1993WO1993003351A1 Amino acid, ester and/or catechol contrast agents for mri
02/18/1993WO1993002708A1 Novel reagent for tumour imaging and therapy
02/18/1993WO1993002652A2 Modified haptens useful as imaging and therapeutic agents
02/18/1993CA2115275A1 Amino acid, ester and/or catechol contrast agents for mri
02/17/1993EP0527131A1 Chelants
02/17/1993CN1069027A Aminocarboxylate ligands having substituted aromatic amide moieties
02/16/1993US5187264 Technetium chelates to be used for determining the renal function
02/16/1993US5187154 Administering cholecystokinins
02/16/1993US5187153 Methods of treatment using Alzheimer's amyloid polypeptide derivatives
02/16/1993US5186923 Enhancement of cellular accumulation of lipophilic cationic organometallic compounds by reduction of intramembrane potential
02/16/1993US5186921 3-methoxy-n(1-ethyl-2-pyrrolidinyl)methyl)naphthyl-2-carboxy amide compounds for imaging human brains; good retention stability
02/16/1993US5186913 Tungsten-188/carrier-free rhenium-188 perrhenic acid generator system
02/10/1993EP0527056A1 Novel reagent for tumour imaging and therapy
02/10/1993EP0403524B1 Preparation of nitruro compounds usable as radio-pharmaceutical products
02/10/1993CN1068744A Asialoglycoprotein-conjugated medicinal agent
02/09/1993US5185368 Complex with trivalent metal ions; medical diagnosis and therapy
02/09/1993US5185142 Antigen-specific composition and in vivo methods for detecting and localizing an antigenic site and for radiotherapy
02/04/1993WO1993002105A1 Trifunctional compounds having specificity for multi-drug resistant cells
02/04/1993WO1993002045A1 Hydroxamate and hydrazide derivatives of polyamines and their medical use as chelating agents
02/04/1993WO1993000064A3 Evaluation and treatment of the multidrug resistance phenotype
02/04/1993WO1992019213A3 Enhancement of abnormal tissue uptake of antibodies, tumor-specific agents or conjugates thereof for diagnostic imaging or therapy
02/04/1993WO1992013950A3 NUCLEOTIDIC SEQUENCES CODING FOR VARIABLE REGIONS OF β CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDIC SEGMENTS AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
02/04/1993CA2113578A1 Trifunctional compounds having specificity for multi-drug resistant cells
02/02/1993US5183653 Boronic acid adducts of metal dioxime complexes useful in labelling proteins and other amine-containing compounds
02/02/1993CA2074867A1 Aminocarboxylate ligands having substituted aromatic amide moieties
01/1993
01/27/1993EP0524722A1 Thiol-reactive maleimido-based radiolabeling reagents
01/27/1993EP0524639A2 Process for the labelling of substances with technetium or rhenium
01/26/1993US5182107 Delivering nerve growth factor across blood brain barrier to brain
01/23/1993WO1993001839A1 Radiopharmaceutical product having in particular a cerebral tropism comprising a transition metal nitride complex, and preparation method therefor
01/23/1993CA2113830A1 Radiopharmaceutical product having in particular a cerebral tropism comprising a transition metal nitride complex, and preparation method therefor
01/21/1993WO1993001303A1 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
01/21/1993WO1993001302A1 Tumor, carbohydrate antigen specific monoclonal antibody and cell line
01/21/1993WO1993000934A1 Tissue specific imaging agents using internal image anti-idiotypic antibodies
01/21/1993WO1993000927A1 Cancer treatment
01/21/1993WO1993000908A1 Elam-1 receptor ligands as diagnostic compounds
01/21/1993DE4124121A1 Small-particle grading system - suspends and filters in successive phases causing swelling and shrinkage
01/21/1993CA2110819A1 Tissue specific imaging agents using internal image anti-idiotypic antibodies
01/14/1993DE4128183C1 New technetium complexes and corresp. complexing agents - useful for measurement of cerebral perfusion, diagnosis of Alzheimer's disease or epilepsy and localisation of tumours
01/13/1993EP0522007A1 A fonctionalized complexand
01/13/1993EP0521954A1 Technecium complexes of thioethers.
01/07/1993WO1993000443A1 Purification of recombinant apolipoprotein e from bacteria
01/07/1993WO1993000064A2 Evaluation and treatment of the multidrug resistance phenotype
01/07/1993WO1992019573A3 Multifunctional ligand for use as a diagnostic or therapeutic pharmaceutical
01/07/1993WO1992019210A3 Serotinin reuptake inhibitors for s.p.e.c.t imaging
01/07/1993EP0521842A2 Tumor antigen specific antibody
01/05/1993US5177192 Method for labeling antibodies with a metal ion
01/05/1993US5176617 Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct
12/1992
12/29/1992US5175343 For detection, radiotherapy and radeoimaging of tumors
12/29/1992US5175269 Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group
12/29/1992US5175257 Useful for delivering radioisotopes to desired target sites in vivo
12/29/1992US5175256 Protein labeling reagents
12/23/1992WO1992022583A2 Tri- and tetra-valent monospecific antigen-binding proteins
12/23/1992WO1992022334A1 Platelet receptor antagonists useful in detecting intravascular platelet aggregation
12/23/1992EP0518982A1 Method for enhancing antibody transport through capillary barriers
12/22/1992CA1311700C Production and characteristics of anti-myosin mouse monoclonal antibody
12/20/1992WO1992022310A1 Asialoglycoprotein-conjugated medicinal agent
12/20/1992CA2089881A1 Asialoglycoprotein-conjugated medicinal agent
12/16/1992EP0517754A1 Antibody constructs with enhanced binding affinity
12/15/1992US5171755 Containing water insoluble oil, surfactant; red blood cell substitutes, treating cardiovascular disorders
12/15/1992US5171749 Wavelength-specific cytotoxic agents
12/15/1992US5171665 Monoclonal antibody to novel antigen associated with human tumors
12/15/1992US5171563 Cleavable linkers for the reduction of non-target organ retention of immunoconjugates
12/10/1992WO1992021379A1 Radiolabeled metal-binding protein for the treatment of arthritis
12/09/1992EP0516873A1 A method and kit for protein labelling with 99 mTC
12/08/1992US5169933 Covalently-linked complexes and methods for enhanced cytotoxicity and imaging