Patents
Patents for A61K 51 - Preparations containing radioactive substances for use in therapy or testing in vivo (24,291)
07/2000
07/26/2000EP1021205A1 Synthesis of ferrocenyl phenyltropane analogs and their radio-transformation to technetium neuroprobes for mapping monoamine reuptake sites
07/26/2000EP0643583B1 Intraoperative, intravascular and endoscopic tumor and lesion detection and therapy
07/25/2000US6093399 Specific blood coagulation exemplified by in vivo coagulation of tumor vasculature, causing tumor regression, through the site-specific delivery of a coagulant using a bispecific antibody
07/25/2000US6093383 Bisamine bisthiol radiolabel binding moieties
07/25/2000US6093382 Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
07/25/2000US6093381 Combining chemotherapeutic agent with lymph node lymphocytes which have been cultured under mitogenic stimulation conditions, or supernatant of it enriched in tumor reactive cells, administering such combination to the cancer patient
07/20/2000WO2000041514A2 Conjugates of colony stimulating factors for targeting and imaging infection and inflammation
07/20/2000WO2000014537A3 Immunoconjugate for diagnosis of multidrug resistance
07/20/2000WO1999064048A9 Inhibitors of hiv reverse transcriptase
07/19/2000EP1019102A2 ?32 p-polyphosphazene
07/19/2000EP1019095A1 Method for the preparation of facial metal tricarbonyl compounds and their use in the labelling of biologically active substrates
07/19/2000EP0772628B1 Peptide derived radionuclide chelators
07/18/2000US6090924 Human-Human CLNH5-specific antibodies
07/18/2000US6090563 Growth differentiation factor-6
07/18/2000US6090408 Crosslinked lipids; in situ detection
07/18/2000US6090366 Process for the preparation of an organ specific antibodies labeled with technetium-99m
07/18/2000US6090365 Radioimmunotherapy of lymphoma using anti-CD20 antibodies
07/18/2000CA1341053C Polypeptide and protein derivatives and process for their preparation
07/13/2000WO2000040597A1 Method and composition for angiogenesis inhibition
07/13/2000WO2000040591A1 Protonated/acidified nucleic acids and methods of use
07/13/2000WO2000040585A1 Cryptate compounds and methods for diagnosis and therapy
07/13/2000WO2000040275A2 The preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning
07/13/2000WO2000040264A1 Method for diagnosing, imaging, and treating tumors using restrictive receptor for interleukin 13
07/13/2000WO2000040229A2 Synergistic tumorcidal response induced by histamine
07/13/2000CA2358754A1 Synergistic tumorcidal response induced by histamine
07/13/2000CA2358570A1 Protonated/acidified nucleic acids and methods of use
07/13/2000CA2358427A1 Method for diagnosing, imaging, and treating tumors using restrictive receptor for interleukin 13
07/12/2000EP1018343A1 Use of p97 and iron binding proteins as diagnostic and therapeutic agents
07/12/2000EP1017817A2 Mutants of thyroid stimulating hormone and methods based thereon
07/12/2000EP1017684A1 Contrasting agent for infarct and necrosis imaging
07/12/2000EP1017424A1 Lipophilic metal complexes for necrosis and infarct imaging
07/12/2000EP1017318A1 Method of imaging cell death in vivo
07/11/2000US6087109 Antisense agent which associated with a heat stable toxin receptor; for diagnosis and prevention of intestinal cancers in humans; anticarcinogenic agents .
07/11/2000US6086850 Calcitonin receptor binding reagents
07/11/2000US6086849 Reagent for preparing a scintigraphic imaging agent, comprising a specific binding peptide having a radiolabel binding moiety that forms a neutral complex when bound to a radioisotope
07/11/2000CA2168775C Tris(isonitrile)copper(i) sulfates for preparing radionuclide complexes
07/06/2000WO2000038681A1 Liposomic niflumic acid - new transdermal anti-inflammatory medicine
07/06/2000WO2000018331A3 Drug delivery systems
07/06/2000CA2357765A1 Liposomic niflumic acid - new transdermal anti-inflammatory medicine
07/05/2000EP1015884A1 Methods of identifying molecules that home to angiogenic vasculature in tumors
07/05/2000EP1015585A2 Tie ligand homologues
07/05/2000EP0853487B1 Neutralizing monoclonal antibodies to respiratory syncytial virus
07/05/2000EP0692982B1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS
07/05/2000EP0528891B1 Method for increasing blood-brain barrier permeability
07/04/2000US6083966 Thiazoline acid derivatives
07/04/2000US6083936 Treatment of estrogen-dependent disorders such as estrogen-dependent cancers; also useful in diagnostic techniques such as magnetic resonance imaging and magnetic resonance spectroscopy
07/04/2000US6083502 Methods for detecting the antigen and its expression level as an indication of the presence of tumor cells
07/04/2000US6083481 Radiolabeled reagents that are scintigraphic imaging agents for imaging sites of thrombus formation in vivo
07/04/2000US6083480 Calcitonin receptor binding reagents
07/04/2000US6083479 Use of tetraazamacrocycle compounds
07/04/2000US6083478 Consists of a cytotoxic radionuclide and a homodimer comprising two heavy chains encoded by the expression vector designated cd4-igg2-pcdna1 (atcc no. 40952)
07/04/2000US6083477 Useful therapeutic reagents for treating leukemias and lymphomas;conjugate of a non-immunogenic rnase or a therapeutic radionuclide that is an alpha-emitter or a beta-emitter and a cell-specific cytokine
06/2000
06/29/2000WO2000037451A1 Il-5 inhibiting 6-azauracil derivatives
06/29/2000WO2000009076A8 Imaging with tc-99m labeled fibrin-alpha-chain peptide
06/29/2000WO1999055386A3 Stimulus sensitive gel with radioisotope and methods of making
06/29/2000WO1998020909A3 Ex-corpore method for treating human blood cells
06/29/2000DE19860289A1 Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium New chelators and their tricarbonyl complexes with technetium and rhenium
06/29/2000CA2354511A1 Il-5 inhibiting 6-azauracil derivatives
06/28/2000EP1013642A2 Chelating agents and the technetium and rhenium tricarbonyl complexes thereof
06/28/2000EP1013285A2 Urokinase-type plasminogen activator receptor
06/28/2000EP1012563A1 Breath test for detection of drug metabolism
06/28/2000EP1012320A2 Use of multivalent chimeric peptide-loaded, mhc/ig molecules to detect, activate or suppress antigen-specific t cell-dependent immune responses
06/28/2000EP1012190A1 Eosinophil eotaxin receptor
06/28/2000EP1012159A1 Detection and treatment of breast, gynecological and prostate cancer
06/28/2000EP1011738A1 Imaging agents for early detection of cardiovascular plaque
06/28/2000EP1011737A2 Method for treating proliferative diseases by therapy
06/28/2000EP1011654A1 A method of modulating cellular activity
06/28/2000EP0915710B1 Stable radioiodine conjugates and methods for their synthesis
06/27/2000US6080785 Reacting a alkylnedi-primary amine compound with a protective group such as trifluoroacetyl or benzyl group reagent to form an intermediate, reacting the intermediate with haloacetic tert-bytyl ester to form ester groups, deprotecting
06/27/2000US6080777 Taxol as a radiation sensitizer
06/27/2000US6080384 Composition made by mixing a stannous salt excluding tin hydroxide with a buffer and organic solvent, admixing with a sulfhydryl-containing biomolecule and lypholizing; mixing the composition with radionuclide to directly bond the isotope
06/27/2000US6080383 Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic agents into radioactive toxic precipitates in the cancer
06/22/2000WO2000035887A2 Vitronectin receptor antagonist pharmaceuticals
06/22/2000WO2000035492A2 Vitronectin receptor antagonist pharmaceuticals
06/22/2000WO2000004954A3 Novel urokinase inhibitors
06/22/2000WO1999061071A3 Assay in vivo of labeled triplex-forming oligonucleotides
06/22/2000CA2727746A1 Quinolone vitronectin receptor antagonist pharmaceuticals
06/22/2000CA2349501A1 Quinolone vitronectin receptor antagonist pharmaceuticals
06/22/2000CA2349333A1 Vitronectin receptor antagonist pharmaceuticals
06/21/2000EP1009726A1 Fluorination of proteins and peptides for f-18 positron emission tomography
06/21/2000EP1009447A1 Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same
06/21/2000EP1009446A1 Imaging methods and compositions
06/20/2000US6077499 First conjugate of a tumor targeting moiety, a therapeutic agent, and first member of a binding pair; clearing agent; and second conjugate of the complementary binding member of the binding pair, and second therapeutic agent
06/20/2000US6077413 Preparing an implantable medical device having a radioactive metallic surface for use in preventing restenosis in atherosclerotic coronary arteries that have been subjected to percutaneous transluminal coronary angioplasty
06/20/2000CA1341035C Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them.
06/15/2000WO2000033891A1 Methods for detection of vulnerable plaques using a detectable lipid-avid agent
06/15/2000WO2000033874A2 Boron neutron capture therapy using pre-targeting methods
06/15/2000WO2000033816A1 Formulation for delivery of particulate material to mucosal membranes
06/15/2000WO2000015231A8 Adenosine a3 receptor modulators
06/15/2000WO1999066951A3 Use of bi-specific antibodies for pre-targeting diagnosis and therapy
06/14/2000EP1007696A1 Il-13 receptor specific chimeric proteins and uses thereof
06/14/2000EP1007504A1 Sterilized 5-aminolevulinic acid
06/14/2000EP1007106A1 Combinatorial library
06/14/2000EP1007101A2 Improvements in or relating to diagnostic/therapeutic agents
06/13/2000US6075130 Calixarene containing upper rim and a lower rim, atleast one ionizable group attached to lower rim and a radionuclide ion from lantahnide elements bound to ionizable group
06/13/2000US6075010 Small molecular weight ligand-hexose containing clearing agents
06/13/2000US6074627 Stable complex
06/13/2000US6074626 Radioactive cisplatin in the treatment of cancer
06/13/2000CA2118309C Lymphocyte activation antigen hb15, a member of the immunoglobulin superfamily
06/13/2000CA2000979C Specific ligands of receptors of oestrogen and progesterone steroidal hormones, use and synthetic intermediates