Patents for A61K 49 - Preparations for testing in vivo (35,376)
07/1999
07/06/1999US5919923 Meso-substituted tripyrrane compounds, compositions, and methods for making and using the same
07/06/1999US5919922 Fluorescent dyes free of aggregation and serum binding
07/06/1999US5919753 Crosslinking a protein or carbohydrate substrate to form crosslinked substrate in which crosslinking groups are biodegradable; i.e. crosslinking galactose with methylene diacrylate; ultrasound contrast agent
07/06/1999US5919643 Methods and compositions for the use of apurinic/apyrimidinic endonucleases
07/06/1999US5919442 Hyper comb-branched polymer conjugates
07/06/1999US5919434 Polymeric surfactant-encapsulated microbubbles and their use in ultrasound imaging
07/06/1999US5919433 Macrocyclic metal complex carboxylic acids, their use as well as process for their production
07/06/1999US5919432 Polyaminated ligands and metal complexes thereof
07/06/1999US5919431 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production
07/01/1999WO1999032513A1 Protein binding polypeptides
07/01/1999WO1999032154A1 Dendritic polymer-saccharide conjugate, pharmaceuticals containing said conjugate, method for its production and use thereof
07/01/1999WO1999032143A1 Thrombogenic polypeptide chimeras and conjugates having activity dependent upon association with tumor vascular endothelium
07/01/1999WO1999032083A1 Microparticles and their therapeutic or diagnostic use
07/01/1999WO1999032034A1 Improvements in or relating to ultrasonography
07/01/1999DE19758118A1 Polyrotaxane Polyrotaxanes
07/01/1999CA2318434A1 Thrombogenic polypeptide chimeras and conjugates having activity dependent upon association with tumor vascular endothelium
07/01/1999CA2316171A1 Microparticles and their therapeutic or diagnostic use
07/01/1999CA2315301A1 Protein binding polypeptides
06/1999
06/30/1999EP0925061A1 Compositions comprising microparticles of water-insoluble substances and method for preparing same
06/30/1999EP0755248B1 Gelified microspheres, method of preparation and applications
06/30/1999EP0730573B1 Iodinated derivatives, preparation and use thereof as contrast agents in x-ray radiology
06/29/1999US5916596 Water insoluble drugs and drug delivery
06/29/1999US5916561 Monoclonal antibody against CD44v6
06/29/1999US5916558 Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
06/29/1999US5916539 Superparamagnetic particles, process for producing the same and their use
06/29/1999US5916538 Administering to a subject an effective dose of glucose labelled with carbon, measuring lelvels of exhaled carbon dioxide for a specific time and compare the level to normal is indicative of diabetic condition
06/29/1999US5916537 Diagnostic and diagnosis method for central nervous abnormality and phenylketonuria
06/24/1999WO1999031183A1 Novel dye-polysaccharide-conjugates and the utilization thereof as a diagnostic
06/24/1999WO1999031119A1 Platelet derived growth factor (pdgf) nucleic acid ligand complexes
06/24/1999WO1999030745A2 Dota-biotin derivatives
06/24/1999WO1999030744A1 Polyrotaxanes
06/24/1999WO1999030743A1 Methods for evaluating a compound for its effect on skin
06/24/1999WO1999030620A1 Optoacoustic contrast agents and methods for their use
06/24/1999WO1999019359A9 Cellular receptor for hiv-1 vpr essential for g2/m phase transition of the cell cycle
06/24/1999DE19758105A1 New dendritic polymer-saccharide conjugates
06/24/1999CA2315207A1 New dye-polysaccharide conjugates and their use as a diagnostic agent
06/23/1999EP0923944A1 Diagnostic composition for diseases accompanied by autoimmune reactions caused by 65k-glutamic acid decarboxylase
06/23/1999EP0923738A1 Methods and compositions for the use of apurinic/apyrimidinic endonucleases
06/23/1999EP0923588A1 Bismuth dendrimers, processes for their preparation, and their use as x-ray contrast agents
06/23/1999EP0923537A1 Process for the preparation of contrast agents
06/23/1999EP0923383A1 Novel dispersible lipid blends and uses therefor
06/23/1999EP0782563B1 Polyiodinated compounds, preparation and use thereof in x-ray radiology
06/23/1999EP0605522B1 Methods for the production of humanized antibodies
06/23/1999EP0565668B1 Biological stain composition, method of preparation and method of use for delineation of epitheleal cancer
06/22/1999US5914265 Keratin K1 expression vectors and methods of use
06/22/1999US5914260 Fish pancreatic disease virus
06/22/1999US5914097 Reacting an anhdride with amino acid or ester or amide to form a polydentate amino-acyl type chelator
06/22/1999US5914095 Polychelants containg amide bonds
06/22/1999CA1340603C Tri-aza macrocycles and metal complexes thereof
06/17/1999WO1999030163A1 Skin test for schizophrenia
06/17/1999WO1999016420A9 Stabilized preparations for use in nebulizers
06/17/1999WO1999015541A3 Use of a pentopyranosyl nucleoside for producing an electronic component, and conjugates of said pentopyranosyl nucleoside
06/17/1999WO1999015539A3 Pentopyranosyl nucleoside, and production and use of the same
06/17/1999DE19803206C1 New tetrakis-carboranylmethyl-propane derivatives useful in boron neutron capture tumor therapy or as labeling agents in energy filtering transmission electron microscopy
06/16/1999EP0922700A1 Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging
06/16/1999EP0921822A1 Animal model for transplantation
06/16/1999EP0757690A4 Electron-deficient porphyrins and processes and intermediates for preparing same
06/16/1999EP0581842B1 An organ specific emulsion
06/15/1999US5912257 Two-photon upconverting dyes and applications
06/15/1999US5911972 Stable microbubbles suspensions injectable into living organisms
06/15/1999US5911971 Nmr contrast media which can mark the vasal space (blood pool agent); uniform and high enough molecular weight to be retained in blood vessel but small enough to be eliminated by the kidney; polyaminoamides; macromolecules
06/10/1999WO1999015540A3 Method for producing a pentopyranosyl nucleoside
06/10/1999CA2254261A1 Metallic chelates of macrocyclic polyaminocarboxylic derivatives and their application to diagnostic imagery
06/09/1999EP0920451A1 Novel peptides suitable for use in antigen specific immunosuppressive therapy
06/09/1999EP0920433A1 Tin dendrimers, their use as x-ray contrast agents and processes for their preparation
06/09/1999EP0920411A1 Diagnostic imaging contrast agent with improved in-serum-relaxivity
06/09/1999EP0920277A1 Laser opto-acoustic imaging system
06/09/1999CN1219135A Method of T1-weighted magnetic resonance imaging of RES organs
06/08/1999US5910300 Amphiphilic linkers for coupling administrable diagnostically or physiologically active agents and bioselective targeting compounds
06/03/1999WO1999027129A1 Virulence-associated nucleic acid sequences and uses thereof
06/03/1999WO1999026970A1 NOVEL pth
06/03/1999WO1999026535A1 Reagent for tumor therapy and/or imaging
06/03/1999WO1999013918A3 Icam-1 selective echogenic microbubbles
06/03/1999CA2310841A1 Reagent for tumor therapy and/or imaging
06/03/1999CA2310561A1 Virulence-associated nucleic acid sequences and uses thereof
06/03/1999CA2223373A1 Process for the preparation of crystalline and solvent free iohexol
06/02/1999EP0919540A1 Process for the preparation of purified crystalline iohexol
06/02/1999EP0918546A2 Improvements in or relating to contrast agents
06/02/1999EP0918511A2 Lipid-binding proteins and their therapeutic and diagnostic use
06/02/1999EP0918508A1 Improved masking of liposomes from res recognition
06/02/1999EP0599946B1 Fullerene compositions for magnetic resonance spectroscopy and imaging
06/01/1999US5908969 Method of detecting prions in a sample and transgenic animal used for same
06/01/1999US5908788 A screening by obtaining urine samples and measuring concentration of medication or metabolites and urine specific gravity to determine normalized urine concentrations
06/01/1999US5908757 Diagnosing by measuring complex formation of smooth muscle myosin heavy chain found in blood sample with specific antibodies; detecting increases levels
06/01/1999US5908610 Stable microbubble suspensions comprising saturated phospholipios for ultrasonic echography
05/1999
05/27/1999WO1999025857A2 Transgenic models of inflammatory disease
05/27/1999WO1999025390A1 A method for detecting chitin-containing organisms
05/27/1999WO1999025389A2 Magnetic resonance imaging agents for the detection of physiological agents
05/27/1999WO1999025388A1 In vivo stain composition, process of manufacture, and methods of use to identify dysplastic tissue
05/27/1999WO1999025243A1 Apparatus for fluid administration
05/27/1999DE19813174A1 Gas-filled microparticles, used for administering biologically active substances
05/27/1999CA2309996A1 Apparatus for fluid administration
05/27/1999CA2309807A1 Transgenic models of inflammatory disease
05/27/1999CA2309749A1 Magnetic resonance imaging agents for the detection of physiological agents
05/26/1999EP0917474A2 Pseudopolyrotaxanes
05/26/1999CN1217314A Process for preparation of crystalline and solvent free iohexol
05/25/1999US5907079 MSH2 disrupted mice develop lymphomas
05/25/1999US5906994 Metal/iodine cluster, complexed with one or more ligand compounds; contrast agent for x-ray images
05/25/1999US5906807 Enhanced contrast for nuclear magnetic resonance
05/20/1999WO1999024490A1 Strictly alternating poly(alkylene oxide ether) copolymers