Patents
Patents for A61K 38 - Medicinal preparations containing peptides (316,240)
04/2010
04/28/2010CN1596266B Specific binding agents of human angiopoietin-2
04/28/2010CN1555417B Paramyxovirus vector for gene transfer to the cardiovascular system
04/28/2010CN1524579B Composite viscoelastic preparation
04/28/2010CN1496271B Method of treating diseases in association with decrease in expression of AOP-1 gene or AOP-1 and remedies for diseases
04/28/2010CN1468307B Anti-dual integrin antibodies, compositions, methods and uses
04/28/2010CN101698852A Protein or polypeptide with function of CD137L, and gene and application thereof
04/28/2010CN101698682A Double-functional fusion protein based on antibacterial peptide, preparation method and applicaitoin thereof
04/28/2010CN101698681A Chimeric polypeptide with dual-targeting function and applications thereof
04/28/2010CN101698678A Silkworm antibacterial peptide, cDNA sequence thereof and application thereof
04/28/2010CN101698103A Medicine composite for treating B type diabetes
04/28/2010CN101698099A Traditional Chinese medicine for treating diabetes
04/28/2010CN101698098A Preparation method of sustained release preparation of phytohemagglutinin
04/28/2010CN101697979A Officinal fungus mycelium extract and preparation method thereof
04/28/2010CN101697971A Rehabilitation therapy method for lung cancer
04/27/2010USRE41288 increasing insulinotropic response in ischemia and treating reperfusion and injured brain cells after an ischemic event by administering glucagon-like peptide-1 and a pharmaceutical carrier for a time sufficient and under conditions effective to increase insulinotropic response which produces insulin
04/27/2010USRE41287 Cyclic agonists and antagonists of C5A receptors and G Protein-coupled receptors
04/27/2010USRE41286 cartilage regeneration and repair product that induces cell ingrowth into a bioresorbable material and cell differentiation into cartilage tissue; comprises at least one TGF beta protein and at least one bone morphogenetic protein
04/27/2010USRE41277 protein D is an Ig receptor for human IgD and has an apparent molecular weight of 42,000; protein D can be detected in all of 116 encapsulated and non-encapsulated isolates of H. influenzae studied
04/27/2010USRE41276 Strains of bacteria characterized by exhibiting a 7 alpha-dehydroxylase activity of less than 50%, and bile acid deconjugation activity of less than 50%, and descendants, mutants and derivatives thereof; for preventing and treating diseases associated with or caused by an altered metabolism of bile acids
04/27/2010US7705196 sFRP expression enhancing agent
04/27/2010US7705195 Screening method
04/27/2010US7705140 DNAs encoding TNF receptor family members
04/27/2010US7705134 immunoglobulins; fibronectins; drug screening
04/27/2010US7705129 Replikin peptides in rapid replication of glioma cells and in influenza epidemics
04/27/2010US7705128 Comprises interleukin-1 zeta polypeptides (IL-1) for diagnosis, prevention and treatment of tumors, allergies and infectious diseases
04/27/2010US7705125 Botulinum neurotoxin type E having increased biological half-life for use treatment and prevention of autonomic, neuromuscular and pain disorders
04/27/2010US7705124 Leucine-based motif and clostridial neurotoxins
04/27/2010US7705123 Fusion protein contains antibody fragment, or Fc fragment; biodrug for use in the treatment and prevention of autoimmune and cancer diseases
04/27/2010US7705119 A Deltorphin-E polypeptide having a specific amino acid sequence and acarrier; antishock agents; opiod receptor agonists; nucleotide sequence;hypertensive agents; antiinflammatory agents; antiischemic agents; surgery;restoring perfusion to organs and tissues; prophylaxis
04/27/2010US7705118 Methods for preparing internally constrained peptides and peptidomimetics
04/27/2010US7705117 EGFH2 genes and gene products
04/27/2010US7705116 Method and system for solubilizing protein
04/27/2010US7705050 Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils
04/27/2010US7705016 administering small molecule capable of inhibiting CPT1(carnitine palmitoyl transferase1) is 2-tetradecylglydate (TDGA) or (R)-N-(tetradecylcarbamoyl)-aminocarnitine
04/27/2010US7705012 7-iminomethyl or 7-oxymethyl camptothecin derivatives conjugated, possibly by means of suitable spacers, to cyclopeptide derivatives containing the arginine-glycine-aspartic acid sequence; anticarcinogenic, antimetastasis agent; high affinity for integrin receptors alpha v beta 3 and alpha v beta 5
04/27/2010US7705006 Anti-cancer cyclopenta[g]quinazoline compounds
04/27/2010US7704987 Metal complex based on 1,10-phenanthroline binds to histidine of the N-terminal loop of the peptide in such a way that the N-terminal loop (amino acid residues 1-15) is blocked or destabilised to inhibit the binding copper, zinc and iron compounds -ones of magnesium /calcium; Alzheimer,s disease
04/27/2010US7704969 Transfection complexes
04/27/2010US7704968 treating cancer with antisense oligonucleotide complementary to a region of a nuclear factor- kappa B(NF- kappa B) subunit mRNA, contains phosphate backbone chemically modified; leukemia, fibroblast cancer; inhibiting septic shock; biocompatibility with no side effect
04/27/2010US7704965 Methods and materials for treating human papillomavirus infections
04/27/2010US7704964 Methods and compounds for the targeting of protein to exosomes
04/27/2010US7704962 Small oligonucleotides with anti-tumor activity
04/27/2010US7704958 Methods and compositions for inhibiting apoptosis using serine protease inhibitors
04/27/2010US7704957 For therapy of AIDS
04/27/2010US7704956 Glutathione-based delivery system
04/27/2010US7704955 polypeptide which can be used to treat, prevent, and modulate pain, inflammation, and metabolic processes in various organisms including plants and animals
04/27/2010US7704954 Method and carrier complexes for delivering molecules to cells
04/27/2010US7704953 construction, expression, and selection of genes that encode novel Trp cage polypeptides with desirable cell and/or tissue binding properties, as well as the novel Trp cage polypeptides themselves; phage display libraries are useful for isolating target specific peptides
04/27/2010US7704952 treating diabetes or obesity using isolated polypeptide is covalently modified with a water-soluble polymer
04/27/2010US7704951 administering as an active ingredient selenoprotein P and/or a peptide fragment or a series of peptide fragments derived from said protein; suitably applicable to diseases with decrease in motor function
04/27/2010US7704950 Methods of using soluble heterodimeric cytokine receptor
04/27/2010US7704949 Perioperative injection of a polypeptide preferential inhibitor of kallikrein, rather than aprotinin, for cardiopulmonary bypass surgery or coronary artery bypass grafting
04/27/2010US7704947 Methods and compositions for the treatment of gastrointestinal disorders
04/27/2010US7704946 Using beta-amyloid, or fragment thereof; anticonvulsants; antiepileptic agents
04/27/2010US7704945 First fusion polypeptide is linked to a second fusion polypeptide via disulfide bond between the heavy chain and light chain polypeptide, where in the first polypeptide binds interleukin-18
04/27/2010US7704944 Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
04/27/2010US7704943 Angiogenesis inhibitors; using transglutaminase; antitumor agents; anticancer agents
04/27/2010US7704924 Library of compounds comprising pyrrolobenzodiazepine moieties
04/27/2010US7704737 culturing with an effective amount of granulocyte-macrophage colony stimulating factor, using brain tissue cells; transplantation; treating multiple sclerosis demyelination
04/27/2010US7704711 Human protein kinases and uses therefor
04/27/2010US7704710 Expression vectors; transformed host cells; culturing the host cell to produce the encoded polypeptide; antiasthmatic agents
04/27/2010US7704709 Recombinant cytokine protein for use in treatment of leukemia
04/27/2010US7704701 Diagnosis of prostate cancer with SPAS-1 cancer antigen
04/27/2010US7704685 In vivo production of a clostridial neurotoxin light chain peptide
04/27/2010US7704525 Lipid microparticles by cryogenic micronization
04/27/2010US7704524 Transdermal botulinum toxin administration for the treatment of spastic muscle pain
04/27/2010US7704514 Vaccines
04/27/2010US7704512 Light chain that cleaves a neurosecretory protein; an HN domain that translocates the light chain across an endosome membrane and a substance P targeting moiety; the HC domain is removed or modified to reduce the targeting of the modified Clostridial toxin to the neuromuscular junction
04/27/2010US7704511 Combination of local botulinum toxin and oral triptan drug administration; preventing overuse; reducing pain sensory output
04/27/2010US7704507 Anticancer vaccine and diagnostic methods and reagents
04/27/2010US7704506 Fcε-PE chimeric protein for targeted treatment of allergy responses a method for its production and pharmaceutical compositions containing the same
04/27/2010US7704505 preventing a respiratory syncytial virus (RSV) infection which is MAb1129 by administering to a human in need thereof an effective amount of a humanized anti-RSV antibody which contains the one CDR from each variable heavy and variable light chain of at least one murine monoclonal antibody
04/27/2010US7704501 Antibodies binding to human ataxin-1-like polypeptide
04/27/2010US7704500 Fusion polypeptide capable of binding vascular endothelial growth factor (VEGF), wherein polypeptide consists of immunoglobulin-like (Ig) domain 2 of a first VEGF receptor and Ig domain 3 of a second VEGF receptor and multimerizing component; use in decreasing or inhibiting plasma leakage; eye disorders
04/27/2010US7704499 Antibody against fragments of apo-lipoprotein B; for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases
04/27/2010US7704498 Antiproliferative agents; anticancer agents; composition comprising antagonist of a human ErbB4 receptor, in admixture with a pharmaceutically acceptable carrier; antagonist selected from group consisting of an antibody produced by a hybridoma selected from the group containing HER4.10H1.1A1
04/27/2010US7704497 Molecules with extended half-lives, compositions and uses thereof
04/27/2010US7704496 For stimulating release of tumor necrosis factor and/or cellular proliferation/differentiation of chondrocytes by contacting blood with polypeptide; cancer diagnosis
04/27/2010US7704492 providing recombinant adeno-associated virus (AAV) virion which comprises an AAV vector, AAV vector comprising selected gene operably linked to control elements capable of directing in vivo transcription and translation of selected gene and introducing recombinant AAV virion into muscle cell or tissue
04/27/2010US7704490 inducing in a patient, at least one activity of IL-2 selected from increasing humoral immune responses and increasing cellular immune responses, by administering to said patient a therapeutically effective amount of a peptide sufficient to induce the activity
04/27/2010CA2449180C Viral polymerase inhibitors
04/27/2010CA2435552C A drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis
04/27/2010CA2400570C Heterologous expression of neisserial proteins
04/27/2010CA2372400C Expression and export of interferon-alpha proteins as fc fusion proteins
04/27/2010CA2328431C Plasmin inhibitors from the australian brown snake pseudonaja textilis textilis
04/27/2010CA2323776C Cytokine receptor common gamma chain like
04/27/2010CA2321149C Antitumor agents
04/27/2010CA2297660C Production of human mutated proteins in human cells by means of homologous recombination
04/27/2010CA2293692C Methods and reagents for vaccination which generate a cd8 t cell immune response
04/27/2010CA2278465C Diagnosis and treatment of myocardial failure
04/27/2010CA2245379C Superpotent calcitonin analogs having greatly increased hypocalcemic action in vivo
04/27/2010CA2203758C Compositions for the detection of proteases in biological samples and methods of use thereof
04/27/2010CA2195653C Cells bearing cd4 decoy receptors and related molecules and methods
04/27/2010CA2179909C Ligand that binds fas antigen
04/27/2010CA2162353C Interferon-.gamma. production inducing polypeptide, monoclonal antibody, and agent for interferon-.gamma. susceptive disease
04/24/2010CA2689482A1 Active agents, compositions, and methods for inhibiting and reversing platelet function
04/24/2010CA2681236A1 Methods and compositions for treatment of fibrosis
04/23/2010CA2643529A1 Method and composition for enhancement of male erectile function
04/22/2010WO2010045586A2 Muc-1 cytoplasmic domain peptides as inhibitors of cancer
04/22/2010WO2010045229A2 Protecting and repairing cartilage and musculoskeletal soft tissues