Patents
Patents for A61K 38 - Medicinal preparations containing peptides (316,240)
01/1999
01/12/1999US5859239 Mercaptoalkanoylamino and acylmercaptoalkanoylamino benzoxazepines and benzothiazepines
01/12/1999US5859230 Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
01/12/1999US5859229 For inhibition of gene expression of human cyclooxygenase 2 by binding to specific untranslated regions of messenger rna; treatment of premature labor, preeclampsia, endometriosis, rheumatoid arthritis
01/12/1999US5859228 Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
01/12/1999US5859223 Dna molecules coding for no more than three short consensus repeats including scr3 of long homologous repeat a of complement receptor 1; antiinflammatory agents; multiple sclerosis; parkinson's/alzheimer's disease
01/12/1999US5859221 Hybrid dna, rna; nuclease resistant
01/12/1999US5859219 Isolated nucleotide sequences used for detection of infection as primers for amplification and probes for hybridization; antiulcer agents; anticancer agents
01/12/1999US5859213 Aqueous β2'-glycoprotein I composition
01/12/1999US5859212 Removing from unlysed cell culture supernatant soluble form of intercellular adhesion molecule-1 by immunoaffinity chromatography; treatment of graft rejection; anti-inflammatory agents, antitumor agents expression
01/12/1999US5859208 Human basic fibroblast growth factor analog
01/12/1999US5859207 Superantigen agonist and antagonist peptides
01/12/1999US5859206 For an isolated polypeptide ligand that binds human p185her2 tyrosine kinase receptor, playing a role in cell growth and differeniation; antitumor/anticarcinogenetic agents
01/12/1999US5859205 Humanised antibodies
01/12/1999US5859204 Non-antigenic, non-immunogenic superior coagulant human/porcine hybrid by site directed mutagenesis; hemophilia
01/12/1999US5859201 G-beta-gamma regulated phosphatidylinositol-3' kinase
01/12/1999US5859200 Human amine transporter
01/12/1999US5859197 Neurogene
01/12/1999US5859195 Isolated amino acid sequence corresponding to the von recklinghausen neurofibromatosis gene
01/12/1999US5859192 Contain amino acid sequences that reacts specifically with a monoclonal antibody secreted by a strain of hybridoma; capable of ensuring transmission of a signal from one cell type to another which may be contiguous or proximal
01/12/1999US5859191 Method for the site-specific modification of peptide alpha amines
01/12/1999US5859189 Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes
01/12/1999US5859186 Methods for producing analgesia
01/12/1999US5859183 Altered telomere repeat binding factor
01/12/1999US5859048 Containing active peptide or protein and tolmetin or salt thereof as mucosal absorption enhancer
01/12/1999US5859031 Small molecule inhibitors of rotamase enzyme activity
01/12/1999US5858994 Carbohydrate conjugates as inhibitors of cell adhesion
01/12/1999US5858990 Treating vascular injury resulting from restenosis following angioplasty
01/12/1999US5858987 E6AP antisense constructs and methods of use
01/12/1999US5858983 Inhibiting binding of cell bearing selectin protein to molecule or cell bearing sialyl-lewis x determinant by contacting with antibody bearing said determinant
01/12/1999US5858982 Cathepsin and methods and compositions for inhibition thereof
01/12/1999US5858981 Modulating the clearance of antibody-coated cells from circulation; modulating the interaction of immune complexes with tissue fc receptors; modulating the activation of immunological processes
01/12/1999US5858980 Peptide fragments of myelin basic protein
01/12/1999US5858979 Anticoagulant peptides
01/12/1999US5858978 Pharmaceutical compositions containing calcitonin gene-related peptide (CGRP) and use thereof to ameliorate hyperimmune mediated diseases and abnormal conditions
01/12/1999US5858977 Method of treating diabetes mellitus using KGF
01/12/1999US5858976 Inhibiting tumor cell growth by administering dna for gene expression of a polypeptide fragment of p53, which regulates cell growth, capable of binding to novel human mdm2, a cancer-causing gene product that normally sequesters p53
01/12/1999US5858975 Oxyntomodulin peptide having cardiotonic activity and insulin release-bromating activity
01/12/1999US5858974 Anti-fungal peptides
01/12/1999US5858973 Polypeptide that transactivates the somatostatin promoter; present in pancreatic duct cells but not in pancreatic alpha-cells; useful in treatment of diabetes
01/12/1999US5858972 Cyclic peptide
01/12/1999US5858971 Cyclic peptide and method of making same by culturing a strain of actinomyces S. nobilis
01/12/1999US5858970 Polypeptide having Factor Xa inhibitory activity
01/12/1999US5858969 Administering to treat adult respiratory distress syndrome
01/12/1999US5858968 Autoimmune model: insulin not used for its endocrinologic effect (does not affect blood sugar levels), but to damp down the host's autoimmune response and prevent autoimmune destruction of pancreatic beta cells, allowing oral dosing
01/12/1999US5858966 Insulin-like growth factor
01/12/1999US5858965 Pharmaceutical compositions for the treatment of autoimmune diseases comprising the B-oligomer of pertussis toxin or its subunits
01/12/1999US5858964 Immunosuppressant
01/12/1999US5858963 Inducing xenograft tolerance and porcine cytokines therefor
01/12/1999US5858962 Composition for treating mastitis and other staphylococcal infections
01/12/1999US5858787 DNA encoding PACAP receptor protein and method for preparing said protein
01/12/1999US5858784 Aerosol transfecting agent
01/12/1999US5858780 Cisplatin resistant cell line
01/12/1999US5858779 Monoclonal antibody, hybridoma, their production and use thereof
01/12/1999US5858777 Methods and reagents for regulating telomere length and telomerase activity
01/12/1999US5858771 Nucleotide sequence coding full length human wild-type retinoblastoma protein used for gene therapy of individuals with predisposition for cancer by replacement of deactivated tumor suppressor gene; anticancer/antitumor agent
01/12/1999US5858758 Human serine protease precursor
01/12/1999US5858756 Polynucleotide and amino acid sequences for cloning, theraputics, and diagnosis; anticancer/antiproliferative agents; aids; antiinflammatory agents; crohn's disease; autoimmune diseases
01/12/1999US5858753 Purified, isolated polynucleotide coding catalytic subunit polypeptide similar to phosphatidylinisitol 3-kinase; anticancer agents; antiproliferative agents
01/12/1999US5858746 Addition polymerization of a water-soluble macromolecular monamer to coat, support, microencapsulate, plug, adhere cells, cell aggregates or tissue
01/12/1999US5858727 Secretion of outer membrane proteins of gram-negative bacteria by means of gram-positive host organisms
01/12/1999US5858723 Immunoassay to detect antibodies in biological fluid from testicular cancer patients using polypeptide antigen from human endogenous retrovirus k10 gag protein, determination of antigen-antibody binding
01/12/1999US5858720 Hiss
01/12/1999US5858719 Polynucleotides encoding human ATP binding-cassette transport protein and methods of use
01/12/1999US5858718 Pcr a
01/12/1999US5858717 Human formin binding protein
01/12/1999US5858716 H2CAA71 polynucleotides
01/12/1999US5858715 Polynucleotide sequence for antisense agents, hybridization probes and diagnosis of diseases; anticancer agents; antiischemic agents; alzheimer's/parkinson's diseases
01/12/1999US5858714 Human metaxin protein
01/12/1999US5858712 CDNA encoding a LEA-motif developmental protein homologous to avian px19
01/12/1999US5858711 Nucleotide sequence coding for protein which interacts with nuclear factor of activated t cell family of proteins to affect immune system response; for assays to determine modulation of protein activity
01/12/1999US5858710 Tumor-associated kazal inhibitor-like polypeptides and encoding polynucleotides
01/12/1999US5858709 Fibronectin binding protein B compounds
01/12/1999US5858708 For genetically engineered expression vectors in host cells, antisense molecules, and diagnosis and treatment of nervous system degenerative disorders such as amyotrophic lateral sclerosis
01/12/1999US5858701 DNA encoding an insulin receptor substrate
01/12/1999US5858689 Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof
01/12/1999US5858688 Gro genes, proteins, and uses thereof
01/12/1999US5858686 Methods for detecting tyrosine kinase-binding target proteins and identifying substances that affect SH2 phosphorylated ligand regulatory systems
01/12/1999US5858684 Contacting recombinant cell with test compound which is not verapamil or gallopamil, determining ability of compound to affect activities of inorganic ion receptor; determination of agonist and antagonist drugs
01/12/1999US5858678 Isolated poypetides which interact with e1b 19kd protein, bcl-2 protein and/or bhrf-1 protein, all associated with cell death; alzheimers disease, spina bifida
01/12/1999US5858677 Protein D--an IgD-binding protein of haemophilus influenzae
01/12/1999US5858675 Double-stranded RNA-binding protein
01/12/1999US5858674 Screening assays to identify agents that modulate cisplatin resistance
01/12/1999US5858670 Screening randomly synthesized oligopeptide- or oligonucleotide-solid phase libraries with acceptor molecules (e.g. antibodies), isolating solid phase support/oligomer bound to molecule, sequencing oligomer
01/12/1999US5858669 Beclin, a novel bcl-2 interacting gene near BRCA1 on chromosome 17q21 and methods of use
01/12/1999US5858661 Isolation, purification, cloned nucleic acid sequence with mutation causing protein truncation or no initiation; detecting carriers by analysis of nucleic acids isolated from patients with hereditary muscular disorders
01/12/1999US5858655 Quantitative analysis by nucleic acid hybridization using oligonucleotide probes from gene; detection of breast cancer, lymphoma, squamous cell cancer and parathyroid adenoma
01/12/1999US5858390 Preparation of cultured undifferentiated mesenchymal cells and injection of the cell preparation
01/12/1999US5858376 Introducing into cell isolated protein derived from herpes simplex virus
01/12/1999US5858366 Immunogenic peptides, antibodies and uses thereof relating to CD4 receptor binding
01/12/1999US5858365 Administering butyric acid and an amino acid, heptafluorobutyric acid, 3-chloropropionic acid, beta-chloro-l-alanine hydrochloride and isobutyramide for ulcers
01/12/1999US5858364 Orally or enterally administering myelin
01/12/1999US5858361 Monoclonal anti-idiotypic anti-CA125 antibodies and pharmaceutical compositions containing them
01/12/1999US5858360 Mediate embryo-endometrium adhesion; anti-trophinin antibodies for inhibition; trophinin-assisting proteins tastin, bystin, lastin for increasing binding; endometrial adenocarcinoma
01/12/1999US5858359 Contacting in vivo blood of human patient with antibody specifically binding to immunoglobulin m to reduce levels of natural xenoreactive antibodies
01/12/1999US5858357 Pharmaceutical composition containing an isolated protease proenzyme, amylase, and aprotinin
01/12/1999US5858355 Infecting in vitro cultured synovial cells with recombinant viral vector comprising dna sequence encoding interleukin-1 receptor antagonist protein linked to promoter, transplanting cells into arthritic joint space for expression
01/12/1999US5858351 Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
01/12/1999US5858347 Therapeutic methods using fusion proteins between interleukin-3 (IL-3) variants and other hematopoietic factors
01/12/1999US5858017 Urologic irrigation solution and method for inhibition of pain, inflammation and spasm
01/12/1999CA2164933C Methods for aiding periodontal tissue regeneration