Patents
Patents for A61K 38 - Medicinal preparations containing peptides (316,240)
03/1999
03/03/1999EP0898580A1 Methods and means for inhibition of cdk4 activity
03/03/1999EP0898578A1 STREPTOCOCCUS PNEUMONIAE TYROSYL-tRNA SYNTHETASE
03/03/1999EP0898577A1 STREPTOCOCCUS PNEUMONIAE METHIONYL tRNA SYNTHETASE
03/03/1999EP0898576A1 Death domain containing receptors
03/03/1999EP0898478A1 Stimulation of host defence mechanisms against tumors
03/03/1999EP0745080B1 Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
03/03/1999EP0677061B1 Polypeptides and anti-hiv agents prepared therefrom
03/03/1999EP0673420B1 Mammalian receptors for interleukin-10 (il-10)
03/03/1999EP0620850B1 Immunogenic detoxified mutants of cholera toxin and of the toxin lt, their preparation and their use for the preparation of vaccines
03/03/1999EP0617122B1 Dna fragment which codes for tumor cell proliferation inhibiting factor
03/03/1999EP0616537B1 CDw52-SPECIFIC ANTIBODY FOR TREATMENT OF MULTIPLE SCLEROSIS
03/03/1999EP0537276B1 Cancer-associated scm-recognition factor, preparation and method of use
03/03/1999CN1209876A Isolated tyrosinase derived peptides and uses thereof
03/03/1999CN1209840A Noval CREBa phenogen
03/03/1999CN1209802A Synthesis and use of retinene derivative having negative hormone and/or antagonist activities
03/03/1999CN1209751A Improved concentrated injection and infusion solutions for intravenous administration
03/03/1999CN1209750A Combined pharmaceutical preparation containing LHRH-analogous substances and anti-estrogens for treating gynaecological disorders
03/03/1999CN1209748A Nucleoside analogs in combination therapy of herpes simplex infections
03/03/1999CN1209747A Modulation of TH1/TH2 cytokine expression by Ribavirin and Ribavirin analogs in activated T-lymphocytes
03/03/1999CN1209739A Medicament forms constituted in situ for releasing enzymes into wounds
03/03/1999CN1209437A Improved method for obtaining isulin precursor having correctly-bonded cystine bond
03/03/1999CN1209436A Human semaphorin L(H-SemaL) and corresponding semaphorins in other species
03/03/1999CN1209435A Chinese trichosanthes protein, preparation method and use in pharmacy
03/03/1999CN1209322A Series product of high-effective neutral calcium-supplementary preparation
03/03/1999CA2242313A1 Signal recognition particle polypeptides and polynucleotides
03/02/1999US5877399 Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
03/02/1999US5877397 Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
03/02/1999US5877313 Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
03/02/1999US5877308 Synthetic oligonucleotide that is complemtary to capl mrna including the 3' splice site thereby inhibiting capl gene expression; anticarcinogenic agents
03/02/1999US5877302 Compacted nucleic acids and their delivery to cells
03/02/1999US5877299 Reacting sample with antibodies against antigens found on differentiated blood cells (e.g. glycophorin a, cd3, cd24, cd16, and cd14), removing labeled cells, recovering unlabeled cell preparation
03/02/1999US5877298 Acellular pertussis vaccines and methods of preparing thereof
03/02/1999US5877296 Reacting disulfide analogs of calicheamicin family with a carrier such as protein, peptide, mono and polyclonal antibodies, their antigen-recognizing fragments and chemically or genetically engineered counterparts
03/02/1999US5877295 Antibodies which bind a subpopulation of Mac-1 (CD11b/CD18) molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen
03/02/1999US5877293 CDR grafted anti-CEA antibodies and their production
03/02/1999US5877291 Multivalent single chain antibodies
03/02/1999US5877290 Humanized antibody fragment that binds a polypeptide sequence encoded by cdna of an anti-hypercalcemic hormone; treatment of electrolyte disorders, kidney failure, bone and heart disorders, osteoporosis, paget's disease
03/02/1999US5877289 Tissue factor compositions and ligands for the specific coagulation of vasculature
03/02/1999US5877288 Recombinant beta-globin with amino acid substitutions which disrupt hydrophobic pocket formed in hemoglobin s; for gene therapy of sickle cell anemia
03/02/1999US5877282 Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
03/02/1999US5877281 Since del-1 is expressed in endothelial cells and certain cancer cells, it may be useful as an endothelial cell and tumor marker. in addition, the ability of del-1 protein to inhibit vascular formation provides for its use as an
03/02/1999US5877278 Solid phase synthesis using two submonomers-an acylating agent, e.g. a haloacetic acid, and a primary amine; cyclization to produce mimetics of drugs; elimination of the necessity of protection groups
03/02/1999US5877277 Octapeptide bombesin analogs
03/02/1999US5877276 Polypeptide agonists for human interleukin-8
03/02/1999US5877275 Recombinant peptide containing the a domain of human cd11b capable of antagonizing cd11/cd18 mediated immune response; treat burns, frostbite, acute arthritis, asthama, respiratory distress syndrome; antiischemic agents
03/02/1999US5877274 Antimicrobial cationic peptides
03/02/1999US5877213 Compositions and methods for therapy and prevention of cancer, AIDS, and anemia
03/02/1999US5877197 C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
03/02/1999US5877179 Cystic fibrosis
03/02/1999US5877174 2,3-diketopiperazine derivatives or their salts
03/02/1999US5877163 Treating aids with 3'-azido-3'-deoxythymidine in combination with interleukin ii or phosphonoformate
03/02/1999US5877162 Short external guide sequences
03/02/1999US5877161 Cyclin D1 negative regulatory activity
03/02/1999US5877156 Cardiovascular disorders
03/02/1999US5877155 Exposure of platelets to the molecule (anti-mimotope) in order to modulate adhesion, aggregation, or agglutination of the platelets.
03/02/1999US5877154 Administering a polypeptide
03/02/1999US5877153 Heparin-binding peptides
03/02/1999US5877152 Method for isolation of highly pure von Willebrand Factor
03/02/1999US5877151 Depending on the dose or concentration of endotoxin, the effects may either be deleterious or advantageous to the host. if excessive tnf-.alpha.,il-1, il-6, and il-8 are produced, they can evoke endotoxic (or septic) shock with symptoms
03/02/1999US5877149 Calibration topical cream or gel
03/02/1999US5877148 Treatment of cancer with human chorionic gonadotropin
03/02/1999US5877147 Muramyl peptide for prophylaxis of cancer
03/02/1999US5877146 Therapeutic use of hemoglobin in the treatment of blood vessel blockage
03/02/1999US5877026 Analgesic peptides from venom of Grammostola spatulata and use thereof
03/02/1999US5877022 Ribozymes targeted to APO(a) RNA
03/02/1999US5877017 Isolated nucleic acid molecule encoding peptides which form complexes with MHC molecule HLA-Cw*1601 and uses thereof
03/02/1999US5877016 Human trk receptors and neurotrophic factor inhibitors
03/02/1999US5877015 APP770 mutant in alzheimer's disease
03/02/1999US5877010 Thymidine kinase mutants
03/02/1999US5877006 DNAs encoding chimeric immunoglobulin light or heavy chains and fragments thereof having variable regions derived from monoclonal antibody 7E3, and vectors and host cells comprising same
03/02/1999US5876999 Preparation of novel streptokinase mutants as improved thrombolytic agents
03/02/1999US5876997 Phytase
03/02/1999US5876985 Methods and compositions for the preparation of recombinant Trichomonas vaginalis proteins and peptides
03/02/1999US5876975 Trehalose phosphorylase its preparation and uses
03/02/1999US5876973 Method for making antibodies which specifically bind to glial growth factors
03/02/1999US5876972 Nucleic acid molecules coding for tumor suppressor proteins and methods for their isolation
03/02/1999US5876971 Amino acid sequence of protein isolated from insects which suck the blood of mammals; anticoagulants; treatment of thromboses or unstable angina or arteriosclerosis; prevention of reblockage of vessels after angioplasty
03/02/1999US5876970 Expressing and recovering recombinantly produced surfactant protein-c, treating with activated derivative of fatty acid, thus forming fatty acid thioesters at cysteine residues; for stable, nonaggregating therapy for premature infants
03/02/1999US5876969 Fusion polypeptide of therapeutic polypeptides attatched to c-and n-terminals of human serum albumin; for high plasma stability, minimization of dosage, side effect reduction
03/02/1999US5876968 Mixture of disulfide bonded dimer of al-milano, lipid lowering agent, and carrier; drug for treatment of athlerosclerosis and cardiovascular disease; prodrug for monomer; prevention of thrombosis
03/02/1999US5876967 Fibroblast growth factor homologous factor-2 and methods of use
03/02/1999US5876966 Compounds and methods for the stimulation and enhancement of protective immune responses and IL-12 production
03/02/1999US5876965 Nucleic acid encoding ARF-19, a novel regulator of the mammalian cell cycle
03/02/1999US5876963 Human nucleotide pyrophosphohydrolase
03/02/1999US5876958 Assays of cells expressing human calcium channels containing α1 β subunits
03/02/1999US5876954 Cytotoxic factor as is associated with multiple sclerosis, its detection and its quantification
03/02/1999US5876950 Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy
03/02/1999US5876948 Screening methods to identify neurotoxin inhibitors
03/02/1999US5876943 Antigenic polypeptide produced by genetic engineering for use in diagnosis of and vaccines to peptic ulcers and stomach cancer
03/02/1999US5876939 Screening for apoptosis modulators by determining alteration of association between cytoplasmic domain of cell surface protein and other proteins in presence of compound; anticarcinogenic agents
03/02/1999US5876931 Identification of genes
03/02/1999US5876923 Screening suppressors which inhibit infected cell protein-4 polypetide by infecting cells with defective alpha-4 gene virus, incubating with compound allowing viral replication, comparing cell pathology
03/02/1999US5876920 Screening for vircides and viral suppressors by contacting infected cell with agent, determining if suppression of prenylation of proteins; against hepatitis virus
03/02/1999US5876919 Incubating compound with tub protein in vitro, detection of complex formed; for modulators of obesity, cachexia, and other eating disorders
03/02/1999US5876761 Sustained release formulations of water soluble peptides
03/02/1999US5876747 Liposome preferentially traveling to cardiac and skeletal muscles
03/02/1999US5876735 Methods for enhancement of protective immune responses
03/02/1999US5876730 Heparin-binding growth factor (HBGF) polypeptides
03/02/1999US5876726 Vaccines and methods for preventing and treating fescue toxicosis in herbivores
03/02/1999US5876722 Hybrid protein