Patents
Patents for A61K 38 - Medicinal preparations containing peptides (316,240)
09/1999
09/14/1999US5952467 Protein which interacts with protein kinase in mitosis; treatment of cardiovascular disorders, septic shock, psoriasis, respiratory diseases, acquired immune deficiency syndrome; antiischemic/antiproliferative agents
09/14/1999US5952466 Reductive alkylation of glycopeptide antibiotics
09/14/1999US5952465 Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
09/14/1999US5952464 Oligopeptide with selective neurotensin receptor affinity labelled with metal isotope or radioactive halogen isotope; for diagnostic imaging and anticarcinogenic agents
09/14/1999US5952461 Process for preparing human proinsulin
09/14/1999US5952371 Triterpene derivatives with immunosuppressant activity
09/14/1999US5952327 Neutral endopeptidase inhibitors; treatment of cardiovascular disorders
09/14/1999US5952311 Photosensitizing chemical means for killing tumor cells, wherein tumoricidal activity is activated by absorbing light or energy within a specific wavelength range, and energy donating chemical means for activating photosensitizer
09/14/1999US5952310 Bactericides
09/14/1999US5952307 Antiinflammatory agents, anticoagulants, antitumor agents
09/14/1999US5952305 Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
09/14/1999US5952304 Platelet-derived growth factor analogues
09/14/1999US5952303 A freeze-dryed artificial pulmonary surfactant comprising kl4 polypeptide and di- and monopalmitoylphosphatidylcholine; storage stability; nonhydrolyzing; reduced viscosity; homogeneity
09/14/1999US5952302 Human therapeutic uses of BPI protein products
09/14/1999US5952301 A synergistic mixture of the peptide hormones, glucagon-like peptide-2 (glp-2) and insulin-like growth factor (igf-1,2) or growth hormone to promote the cell growth in the large and small intestines; nutritional, gastrointestinal disorders
09/14/1999US5952300 Antifungal compositions
09/14/1999US5952299 Cyclic peptide nuclei and derivatives thereof
09/14/1999US5952297 Monomeric insulin analog formulations
09/14/1999US5952296 Method of using relaxin as therapeutic or preventing agent
09/14/1999US5952295 Composition and method for treatment of inflammatory conditions of the gastro-intestinal tract
09/14/1999US5952294 Peptidyl prodrugs and methods of making and using the same
09/14/1999US5952232 Expandible microparticle intracellular delivery system
09/14/1999US5952228 Isolated cytolytic T cells which are specific for complexes OF HLA- B35 molecules and the peptide PHE Pro Ser Asp Ser Trp Cys Tyr PHE, and uses thereof
09/14/1999US5952226 Hypoxia responsive EPO producing cells
09/14/1999US5952225 A packaging cell containing a polynucleotide which codes a portion of a selected retrovirus having at least the envelope protein; for producing vectors resistant to complement inactivation by serum; gene therapy
09/14/1999US5952223 Compositions for the diagnosis and treatment of Chediak-Higashi syndrome
09/14/1999US5952221 A virion having a drug-sensitivity gene and a second gene capable of providing ancillary effects to solid tumor cells; gene therapy and antitumor agents
09/14/1999US5952214 Human growth-related CDC10 homolog
09/14/1999US5952212 Anticarcinogenic agents and antidiabetic agents
09/14/1999US5952199 A protein that contains an immunoglobulin-like domain; antiproliferative/antitumor agents, treatment of rheumatoid arthritis, psoriasis, diabeties, glaucoma, muscular disorders and immune rejection of eye transplants
09/14/1999US5952197 DNA encoding the chemotactic cytokine III
09/14/1999US5952194 Flea nucleic acid sequences and uses thereof
09/14/1999US5952193 Adding a protease to an aqueous solution to hydrolyze whey protein, measuring amount of free amino acid of lysine, phenylalanine, leucine and arginine; terminating hydrolysis reaction at predetermined value; treatment of food allergies
09/14/1999US5952189 Screening for enzyme inhibitors for antiproliferative agents, antitumor agents, treatment for leukemia, acquired immune deficiency syndrome, nervous system disorders
09/14/1999US5952181 Hybridizing polynucleotide sequence to complementary polynucleotide forming a complex, detecting complex formation; anticarcinogenic agent, treatment of psychological disorders, alzheimer's disease
09/14/1999US5952175 DNA encoding a human progesterone receptor complex p23-like protein
09/14/1999US5952034 Increasing the digestibility of food proteins by thioredoxin reduction
09/14/1999US5952011 Human placental transglutaminase polypeptide and nucleotide sequences encoding it, or an allelic variant thereof; use as wound-healing agent
09/14/1999US5952009 Administering beta-lactoglobulin wherein at least one lysine of n-terminal amino acid is modified by an aromatic anhydride selected from trimellitic anhydride, 3-hydroxyphthalic anhydride and trimellitic anhydride chloride
09/14/1999US5952008 Desolventizing a solution with a pharmaceutically active polypeptide and an adjuvant for enhancing the systemic absorption of the peptide dissolved therein; pulverizing the dry solid, optionally agglomerating, loading into inhaler
09/14/1999US5952002 Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or sequences of that virus coding therefor
09/14/1999US5951996 Nonsurgical treatment
09/14/1999US5951989 Method for the treatment of dry skin
09/14/1999US5951984 Administering immunogen selected from group of protein and peptide to mammel, wherein mammel does not ingest a fat-soluble component substance within 4 hours before and within 2 hours after ingestion of the immunogen
09/14/1999US5951983 A light chain framework region derived from a human antibody, a heavy chain framework region derived from a human antibody and light chain cdrs of the non-human monoclonal antibody produced by the cell line deposited as atcc hb11423;
09/14/1999US5951982 Administering an antibody thaat binds an epitope of vcd44; antitumor,-metastasis and carciogenic agents
09/14/1999US5951980 Identification, production and use of new staphylokinase derivatives with reduced immunogenicity
09/14/1999US5951979 Mutants (alanine replacing an aspartic acid) lack or have reduced catalytic activity but retain ability to bind substrate resulting in formation of observable and isolatable complex and less immunogenic effects
09/14/1999US5951976 Vaccinating a mammal by administering a composition comprising an opsonin-enhanced cell comprising said selected antigen with the provision the opsonin does not bind to a receptor for a fragment of c33
09/14/1999US5951974 At least about 15%, preferably about 30%, of the interferon conjugates have a nonantigenic alkylpolyether attached to a preferential histidine residue; high activity; reacting an n-oxycarbonyloxyimide at acidic ph
09/14/1999US5951973 Use of interleukin-4 (IL-4) to treat rheumatoid arthritis
09/14/1999US5951971 Eye-drops for treatment of eye disorders and surrounding area comprising cyclosporin and surfactant selected from polyoxyethylene fatty acid esters, polyoxyethylene alkylphenol ether and polyoxyethylene alkyl ethers
09/14/1999US5951455 Antisense modulation of G-alpha-11 expression
09/14/1999CA2159449C Oesteoblast growth stimulating composition containing pdgf and vitamin d
09/14/1999CA2086087C Growth hormone crystals and a process for production of these gh-crystals
09/14/1999CA2012732C Production of modified pe40
09/14/1999CA1340748C Synthetic hiv protease gene and method for its expression
09/14/1999CA1340747C Hiv-2 virus variants
09/14/1999CA1340742C Process for chromatographically separating plasma proteins, protein concentrates produced, particularly factor viii, fibrinogene, von willebrand factor and fibronectin
09/14/1999CA1340737C Process for the preparation of pasteurized immunoglobulin preparation
09/13/1999CA2226391A1 N-terminal peptides of sdf-1 have functional activities mediated by cxcr4
09/12/1999CA2265209A1 Method of preventing allograft rejection
09/12/1999CA2231952A1 Inhibition of tumor growth
09/10/1999WO1999045135A1 Novel fdrg protein and nucleic acid molecules and uses therefor
09/10/1999WO1999045132A1 Poly zinc finger proteins with improved linkers
09/10/1999WO1999045128A2 Chimeric proteins with cell-targeting specificity and apoptosis-dinducing activities
09/10/1999WO1999045127A2 Enhanced prodrug activation
09/10/1999WO1999045126A2 Enhanced prodrug activation
09/10/1999WO1999045121A1 EPITOPE PEPTIDES IMMUNOGENIC AGAINST $i(STREPTOCOCCUS PNEUMONIAE)
09/10/1999WO1999045117A2 Interferon, ifn-hy and uses thereof
09/10/1999WO1999045116A2 Human homolog of a nuclear migration gene and its use
09/10/1999WO1999045115A1 Human synapse related glycoproteins (hsrp)
09/10/1999WO1999045113A1 Smad binding elements and uses thereof
09/10/1999WO1999045112A2 Chromosome 11-linked coronary heart disease susceptibility gene chd1
09/10/1999WO1999045111A1 Lectomedin materials and methods
09/10/1999WO1999045110A1 V-like domain binding molecules
09/10/1999WO1999045108A2 Novel mechanically sensitive mammal potassium channel family activated by polyunsaturated fatty acids and their use particularly for screening medicines
09/10/1999WO1999045107A1 Novel calpain and dna encoding the same
09/10/1999WO1999045102A1 Method for activating natural killer (nk) cells
09/10/1999WO1999045098A2 Delivery or proteins into eukaryotic cells with recombinant yersinia
09/10/1999WO1999045030A1 Human g-protein coupled receptor (gpr25)
09/10/1999WO1999045029A1 New salt forms of (2e)- 5-amino-5- methylhex-2- enoic acid n-methyl-n-((1r)-1-(n- methyl-n-((1r)-1-(methylcarbamoyl)-2- phenylethyl)carbamoyl)-2- (2-naphtyl)ethyl)amide
09/10/1999WO1999045028A1 Monoclonal antibodies esm-1 protein specific, and use of said antibodies for detecting esm-1 protein
09/10/1999WO1999045027A1 Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes
09/10/1999WO1999045026A1 Method for increasing the serum half-life of a biologically active molecule
09/10/1999WO1999045020A1 Isolation of tissue specific peptide ligands and their use for targeting pharmaceuticals to organs
09/10/1999WO1999045019A1 Isolated nucleic acid molecules which encode tage molecules, and uses thereof
09/10/1999WO1999045000A1 Process for producing 4-thiazolylmethyl derivative
09/10/1999WO1999044645A1 Compositions and methods of treating tumors
09/10/1999WO1999044644A1 Improved eukaryotic expression vector
09/10/1999WO1999044642A1 Pharmaceutical compositions and their use
09/10/1999WO1999044636A2 Il-12 enhancement of immune responses to t-independent antigens
09/10/1999WO1999044635A1 Enhancement of immunity by intranasal inoculation of il-12
09/10/1999WO1999044632A1 Treatment of fibromyalgia with low interferon doses
09/10/1999WO1999044631A1 Topical composition containing human epidermal growth factor
09/10/1999WO1999044630A1 Protein-free preparations
09/10/1999WO1999044629A2 Utilization of cd137 in order to promote the proliferation of peripheral monocytes
09/10/1999WO1999044628A1 Conjugates useful in the treatment of prostate cancer
09/10/1999WO1999044627A1 Use of hexapeptides for the manufacture of a pharmaceutical composition for the treatment of hot flushes
09/10/1999WO1999044625A1 Smallpox inhibitor of complement enzymes (spice) protein and methods of inhibiting complement activation