Patents
Patents for A61K 38 - Medicinal preparations containing peptides (316,240)
10/1999
10/12/1999US5965586 Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
10/12/1999US5965585 Suppressing formation of collagen and collagen-like substances or biosynthesis of procollagen in living systems by administering a hydroxypyridone compound enzyme inhibitor of protein hydroxylase; antiscarring agents
10/12/1999US5965541 Chimeric adenovirus coat protein of non-native amino acid sequence, which directs entry into cells of a vector more efficiently than a vector which is identical but with a wild-type adenovirus coat protein; ex vivo gene therapy
10/12/1999US5965539 Peptidomimetics; anti-cancer drugs
10/12/1999US5965538 Azapeptide derivative
10/12/1999US5965537 Anticancer agents; water solubility
10/12/1999US5965536 Small peptides including the amino acid sequence arg arg trp trp cys xaa, wherein xaa is any amino acid residue are potent inhibitors of cxc intercrine molecules such as interleukin-8; treating inflammatory diseases such as cystic fibrosis
10/12/1999US5965535 Isolated human leukocyte antigen (hla) class ii-binding peptide and amino sequence encoding it; the peptides stimulate the activity and proliferation of cd4+ t lymphocytes
10/12/1999US5965534 Use of ω-conotoxin analogs for treating retinal and optic nerve head damage
10/12/1999US5965533 Atrial natriuretic peptide (ANP) as an additive to peritoneal dialysis solutions
10/12/1999US5965532 Low molecular weight, synthetic crosslinking boron compounds as an agonists or antagonists and induce association between naturally occurring receptors, t cell surface receptor
10/12/1999US5965531 Method of reducing perivascular lesions using insulin-like growth factor I
10/12/1999US5965530 Therapeutic uses of keratinocyte growth factor
10/12/1999US5965528 Inhibiting the proliferation of autoreactive immune cells in a mammal by administering unglycosylated recombinant human alpha-fetoprotein produced by a prokaryotic cell; treating autoimmune diseases such as multiple sclerosis
10/12/1999US5965527 Cyclosporin a sulfided at the 3 position by r-(ch)n-s-by reacting a lithium-activated derivative with the disulfide; synergistic mixture with a retrovirus viricide; side-effect reduction; aids and arc (aids related complex)
10/12/1999US5965526 For design of compounds having biological activity; for inhibiting binding activity of nk2 receptors
10/12/1999US5965525 For inhibiting fungal and parasitic activities
10/12/1999US5965523 Promoting angiogenesis by administering scatter factor
10/12/1999US5965522 Stem cell factor formulations and methods
10/12/1999US5965521 Pulsatile delivery of leptin receptor ligands
10/12/1999US5965520 Therapeutic treatment of rheumatoid arthritis and polymyalgia rheumatica
10/12/1999US5965455 Ryegrass pollen allergen
10/12/1999US5965440 Retroviral vector containing dna operatively linked with three different promters, a tetracyline regulatory unit under transcritpional control of the second promoter, an antisense orientated tetracycline response unit; gene therapy
10/12/1999US5965435 Genetically engineered genes containing the herpes virus of turkeys gc gene, thymidine kinase region of marek's disease virus, infectious laryngotracheitis virus's open reading frame and ribonucleotide reductase genes; for vaccines
10/12/1999US5965430 Bioactive substance having antitumor activity, producing strain, and production thereof
10/12/1999US5965427 Human RAD50 gene and methods of use thereof
10/12/1999US5965423 A polypeptide; diagnosis of cirrhosis, multiple sclerosis, gastrointestinal disorders, respiratory disorders, acquired immune defiency syndrome; antiarthritic/antiischemic/ antiallergens/ antiproliferactive agents
10/12/1999US5965421 Human IRAK-2
10/12/1999US5965420 A protein which stimulates cell proliferation; treatment of bone loss due to osteoporosis; treat adult respiratory disease syndrome, parkinson'disease, huntington's disease; antiarthritic/anticarcinogenic agents; antiallergens
10/12/1999US5965419 Purified sulfotransferase
10/12/1999US5965416 Arginyl tRNA synthetase from staphyloccus aureus
10/12/1999US5965413 Process for producing phosphatidylserines having long chain unsaturated fatty acid as side chain
10/12/1999US5965412 For phosphorolysis of kojibiose in presence of phosphoric acid and/or salt forming d-glucose and beta-d-glucose-1-phosphoric acid and/or salt; for transfer of glucosyl group to other saccharides producing oligosaccharides
10/12/1999US5965403 Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
10/12/1999US5965398 A cell growth inhibitor gene; diagnosis and treatment of breast cancer; anticarcinogenic agents
10/12/1999US5965397 Protein factor, cytokines, lymphokines, interferons, and interleukins, and colony stimulating factors; treatment of osteoporosis, stimulating or bone growth, regeneration of nerve and brain tissue, alzheimer/huntington disease's
10/12/1999US5965394 Human importin alpha homolog
10/12/1999US5965392 A nucleic acid molecule; treating obesity or anorexia
10/12/1999US5965390 Protein L and hybrid proteins thereof
10/12/1999US5965388 Isolated polynucleotides; diagnosis and treatment autoimmune diseases, tissue rejection, allergies, acquired immune deficiency disease; viricides, bactericides and fungicides; anticarcinogenic agents
10/12/1999US5965386 Yeast strains and modified albumins
10/12/1999US5965383 Fibrin binding domain polypeptides and uses and methods of producing same
10/12/1999US5965382 Nucleic acid encoding secreted Mac-2 binding glycoprotein
10/12/1999US5965381 A mutant strain deficient in producing functional effector proteins; used for heterologous protein transfer into antigen presenting cells; treating infections by pathogens; inducing cellular immune response
10/12/1999US5965373 Identifying enzyme inhibitors by combining a dimeric protein with a substrate, and a compound believed to be an inhibitor and determining activity of the protein on the substrate; diagnosis of epithelial cancer
10/12/1999US5965371 Targeting undesired antigens by intracellular expression of antibody capable of binding to the target; delivering a dna sequence with a promoter operably linked to the antibody; expressing antibody and binding antigen in cells of interest
10/12/1999US5965370 Antisense modulation of RhoG expression
10/12/1999US5965367 Purified bradykinin B1 receptor
10/12/1999US5965365 A human growth factor receptor binding gene; treatment and diagnosis of smooth muscle disorders; antiproliferative/ anticarcinogenic/antitumor agents
10/12/1999US5965360 Diagnosis of metastatic cancer by the mts-1 gene
10/12/1999US5965359 Mixing cells from biological sample with detectable labeled complementary dna probe, detecting the presence of the probe that hybridizes with messenger rna for human platelet-derived growth factor receptor gene
10/12/1999US5965157 Method to provide for production of hair coloring pigments in hair follicles
10/12/1999US5965138 Recombinant chimeric virus and vaccine comprising a long viral genomic region from the herpes virus of turkeys and a short viral genomic region from marek's disease virus; immunizing birds
10/12/1999US5965133 Self-assembling multimeric nucleic acid constructs
10/12/1999US5965132 Methods and compositions for targeting the vasculature of solid tumors
10/12/1999US5965131 Galactosylated clearing agent binds to the primary binding site of the primary targeting species, and only non-bound primary targeting species is cleared, not bound species second site is not blocked by the clearing agent
10/12/1999US5965130 Inhibiting metastasis of a tumor in a mammal by administering intravenous immunoglobulin (inig) in a specific dosage either as a sole agent or in combination with other agent used in cancer treatment
10/12/1999US5965129 Purified cathepsin polypeptide and amino acid sequence or immunologically active fragments thereof; administering the novel protein with a pharmaceutical carrier to treat cancer
10/12/1999US5965126 use of mutant alkyltransferases for gene therapy to protect from toxicity of therapeutic alkylating agents
10/12/1999US5965125 Hybrid matrix implants and explants
10/12/1999US5965122 Use of interleukin-7 to stimulate proliferation of hematopoietic cell precursors
10/12/1999US5965121 Compounds and compositions for delivering active agents
10/12/1999US5965120 Lymphocyte chemoattractant factor and uses thereof
10/12/1999US5965119 Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
10/12/1999US5965108 Cyclic peptide-metal complex specifically binds to surface somatostatin receptor-expressing cells; radiology; scintigraphy; antitumor,-carcinogenic and metastatic agents; stability
10/12/1999US5964805 Method and paste for articular cartilage transplantation
10/12/1999US5964729 Perforating device for dermal administration
10/12/1999CA2112423C Non-reducing saccharide-forming enzyme, and its preparation and uses
10/12/1999CA2096851C Tissue plasminogen activator substitution variant
10/12/1999CA1340787C Cdnas coding for members of the carcinoembryonic antigen family
10/12/1999CA1340781C Tumor specific monoclonal antibodies
10/10/1999CA2263059A1 New peptide compounds analogue to glucagon-like-peptide-1 (7-37), their preparation process and the pharmaceutical compositions containing them
10/08/1999CA2267844A1 Use of a combination of an osteoinductive protein and a dorsalizing factor for cartilage induction
10/08/1999CA2234349A1 Method of reducing boar taint
10/07/1999WO1999051051A2 A method for controlling connections to a mobile station
10/07/1999WO1999050670A1 Pf-4 receptor assay
10/07/1999WO1999050658A2 Methods and compounds for modulating nuclear receptor activity
10/07/1999WO1999050643A1 Molecular sensing apparatus and method
10/07/1999WO1999050462A1 Aptamer based bacterial inhibition systems (abbis)
10/07/1999WO1999050461A1 Therapeutic and diagnostic applications based on the role of the cxcr-4 gene in tumorigenesis
10/07/1999WO1999050435A1 Gpi-122, a novel glycophosphatidylinositol-anchored protein
10/07/1999WO1999050425A2 Regulated apoptosis using chemically induced dimerization of apoptosis factors
10/07/1999WO1999050421A1 Ubiquitin conjugating enzyme
10/07/1999WO1999050418A1 Treatment and diagnosis of staphylococcal infections
10/07/1999WO1999050415A2 Protease-activated receptor par4 (zchemr2)
10/07/1999WO1999050414A1 Blk genes, gene products and uses thereof in apoptosis
10/07/1999WO1999050413A2 THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY
10/07/1999WO1999050412A1 HUMAN p51 GENES AND GENE PRODUCTS THEREOF
10/07/1999WO1999050410A1 Novel molecules expressed during muscle development and genetic sequences encoding the same
10/07/1999WO1999050408A1 Novel gene that is amplified and overexpressed in cancer and methods of use thereof
10/07/1999WO1999050405A1 Secreted proteins and polynucleotides encoding them
10/07/1999WO1999050403A2 Method and reagents for the treatment of diseases or conditions related to molecules involved in angiogenic responses
10/07/1999WO1999050398A2 Recombinant anti-tumor rnase
10/07/1999WO1999050396A1 Nek1-related protein kinase
10/07/1999WO1999050394A1 Suppressive monocyte derived cells, process for their preparation and their uses in pharmaceutical compositions
10/07/1999WO1999050392A1 Methods and compositions for eliciting an immune response to a telomerase antigen
10/07/1999WO1999050391A1 Stimulated monocyte derived cells, their preparation and uses
10/07/1999WO1999050386A2 Human telomerase catayltic subunit variants
10/07/1999WO1999050303A2 Immune response modulator alpha-2 macroglobulin complex
10/07/1999WO1999050298A1 GFRα-X, A NOVEL GLIAL-DERIVED NEUROTROPHIC FACTOR RECEPTOR AND USES THEREFOR