| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
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| 04/24/2008 | US20080097102 Aminotetralin-derived urea modulators of vanilloid vr1 receptor |
| 04/24/2008 | US20080097099 Insecticides; for human or veterinary medicine; preparing heterocyclic amide and imine derivatives |
| 04/24/2008 | US20080097094 cis-6-(3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane; for controlling synaptic transmission, neurotransmitter release; Alzheimer's disease, Parkinson's disease, attention deficit disorder, depression, nicotinic withdrawal syndrome, Tourette's syndrome, schizophrenia and pain |
| 04/24/2008 | US20080097087 Micelles; complexes; stability; MALDI-TOF-MS |
| 04/24/2008 | US20080097082 Nucleotide sequences coding recombinant protein for use in prevention and treatment of hyperphosphatemia |
| 04/24/2008 | US20080096981 modulating activities associated with the IL-9 pathway for the treatment of atopic allergies like asthma; autoimmune diseases; new genes tightly expressed in association with an inflammatory response in the airways mediated by type 2 helper T-cells (TH). These genes have been designated TH2AF1 |
| 04/24/2008 | US20080096978 Hydrogen peroxide, sodium perborate, sodium peroxide or urea peroxide, a non-clouding stabilizer chosen from diethylene triamine penta(methylene phosphonic acid) and 1-hydroxyethylidene-1,1-diphosphonic acid, and hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose |
| 04/24/2008 | US20080096974 Polyamine-Metal Chelator Conjugates |
| 04/24/2008 | US20080096973 Z-stilbenes derivatives and the pharmaceutical composition thereof |
| 04/24/2008 | US20080096972 Compound formulations of 2-amino-1, 3-propanediol compounds |
| 04/24/2008 | US20080096971 Treatment of Inflammatory Disorders and Pain |
| 04/24/2008 | US20080096970 Stable Nateglinide Form B Compositions |
| 04/24/2008 | US20080096969 L-N alpha -(menthanecarboxyl)glycine-N-isobutylamide; mixture additionally cause a flavor-modulating effect and/or a trigeminal and/or a salivatory stimulus; on the skin and/or mucous membranes; for nutrition, pleasure, oral hygiene, a pharmaceutical, or a cosmetic; nonhydrolyzing |
| 04/24/2008 | US20080096968 Derivatives of 1-Phenylalkanecarboxylic Acids for the Treatment of Neurodegenerative Diseases |
| 04/24/2008 | US20080096967 Formulations for Injection of Catecholic Butanes, Including Ndga Compounds, Into Animals |
| 04/24/2008 | US20080096965 (Halobenzyloxy) Benzylamino-Propanamides as Sodium and/or Calcium Channel Selective Modulators |
| 04/24/2008 | US20080096964 Food Fortification with Polyunsaturated Fatty Acids |
| 04/24/2008 | US20080096963 Especially bee stings; linoleic acid, oleic acid, lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid, behenic acid, lignoceric acid, or palmitoleic acid; also administered by injection; ointments, creams, gels, patches, powders, sprays, lotions, sticks; antiallergens, antihistamines |
| 04/24/2008 | US20080096962 tert-Butyl 2-{2-[1-ethyl-3-(4-trifluoromethoxy-phenyl)-ureido]-indan-5-ylsulfanyl}-2-methyl-propionate; peroximose proliferator activated receptor antagonist; cardiovascular desease, diabetes; coupling N(5mercapto-indan-2yl)acetamide with (2methyl-2halo) propionate and 2-(4-hydroxyphenoxy)propionic acid |
| 04/24/2008 | US20080096961 Di- and tri-hydroxy derivatives of eicosapentaenoic acid and docosahexaenoic acid coadministered with a cyclooxygenase-2 inhibitor; antiinflammatory agents |
| 04/24/2008 | US20080096960 4-amino-3-(4-chlorophenyl)butanoic acid; prodrugs of baclofen and baclofen analogs; gamma aminobutanoic acid agonist; drug, nicotine, and narcotic abuse; antitussive, antiemetic agent; cough, nausea, vomiting; oral administration; sustained release dosage form |
| 04/24/2008 | US20080096958 9-(3',7'-dimethyl-2',6'-octadienyl)-4'-hydroxy-7H-furo[3,2- gamma ][1]benzopyran-7-one and 8-(3',7'-dimethyl-2',6'-octadienyl)-5-hydroxy-7-methoxy-2H-1-benzopyran-2-one; odorless, tasteless, nontoxic; wider spectrum; foods, cosmetics, drugs |
| 04/24/2008 | US20080096957 Albumin-Binding Conjugates Comprising a Fatty Acid and Peg |
| 04/24/2008 | US20080096955 Histamine-3 receptor antagonists |
| 04/24/2008 | US20080096954 Novel Bicyclic Compounds As Modulators of Androgen Receptor Function And Method |
| 04/24/2008 | US20080096953 N-(2-{2-[(2-Hydroxy-3-isobutyl-3-methyl-4-oxo-cyclobut-1-enyl)-phenyl-methyl]-6-methyl-1H-indol-3-yl}-1,1-dimethyl-ethyl)-acetamide, for example; useful as chymase inhibitors; treatment of allergy, asthma, peripheral arterial occlusive disease, irritable bowel disease |
| 04/24/2008 | US20080096952 Methods for the treatment of atherosclerosis, using substituted phenethylsulfones |
| 04/24/2008 | US20080096951 Carvedilol Monocitrate Monohydrate |
| 04/24/2008 | US20080096950 Compounds Useful In Therapy |
| 04/24/2008 | US20080096949 Indazolyl-substituted pyrroline compounds as kinase inhibitors |
| 04/24/2008 | US20080096948 Serotonin antagonist compositions and methods for the local inhibition of pain and inflammation |
| 04/24/2008 | US20080096947 Polyvinylpyrrolidone or cyclodextrin as a builder, and polysorbate as a wetting agent, are dissolved with imexon in an organic solvent, preferably dimethyl sulfoxide, and lyophylized; lyophilisates are dissolved in aqueous propylene glycol; improved storage stability |
| 04/24/2008 | US20080096946 Tetramethylation of 3,5-di(cyanomethyl)toluene, oxidation of the 1-methyl group to form an aldehyde, conversion to a Boc-protected hydrazone, reduction to a Boc-protected hydrazine, salt formation, conversion to anastrozole; industrial scale, high yield and purity; anticarcinogenic agent; breast cancer |
| 04/24/2008 | US20080096945 Amorphous and Crystalline Forms of Losartan Potassium and Process For Their Preparation |
| 04/24/2008 | US20080096944 Preparing aqueous sodium irbesartan and displacing the sodium with magnesium or calcium ions; solvent-free; easily sterilized aqueous solutions; controlled crystallization, easy filtration and drying; nonelectrostatic behavior and ready tabletting |
| 04/24/2008 | US20080096943 Urea derivatives, for example, 1-(3,5-dimethyl-isoxazole-4-yl)-3-[4-[(4-fluorobenzyl)methylamino]-butyl]-urea; use in treating inflammatory or allergic condition such as an inflammatory or obstructive airways disease |
| 04/24/2008 | US20080096942 Beta-secretase inhibitors; use in treating Alzheimer's disease; for example, N-{(1S,2R)-1-[3-(cyclohexylmethyl)benzyl]-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}acetamide hydrochloride |
| 04/24/2008 | US20080096941 Halogenated benzamide derivatives |
| 04/24/2008 | US20080096940 5-Hydroxy-Benzothiazole Derivatives Having Beta-2-Adrenoreceptor Agonist Activity |
| 04/24/2008 | US20080096939 Process For Preparation Of Pramipexole By Chiral Chromatography |
| 04/24/2008 | US20080096938 Immunosuppressants for autoimmune diseases such as multiple sclerosis, transplant rejection; sphingosine-1-phosphate (S1P) receptor agonists; (S)-2-Amino-2-(5-(4-(2-(pentyloxy)ethoxy)-3-(trifluoromethyl)phenyl)-1,3,4-thiadiazol-2-yl)propyl dihydrogen phosphate for example |
| 04/24/2008 | US20080096937 For example, 2-{4-[(2-chloro-benzyl)-ethyl-amino]-phenyl}-1,1,1,3,3,3-hexafluoro-propan-2-ol; the compounds bind to and selectively activate LXR alpha and LXR beta; used to treat diseases such as atherosclerosis and diabetes |
| 04/24/2008 | US20080096936 Sulfur substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical preparations comprising them |
| 04/24/2008 | US20080096935 Heterocyclic Indanone Potentiators of Metabotropic Glutamate Receptors |
| 04/24/2008 | US20080096934 N-[4-((S)-2-Propylamino-propyl)-phenyl]-4-trifluoromethoxy-benzenesulfonamide; Dipropyl-{2-[4-(4-trifluoromethoxy-benzenesulfonylmethyl)-phenyl]-ethyl}-dipropyl-amine salt, psychological, nervous system disorders such as schizophernia, bipolar, dyskinesias, tourette syndrome, depression, sleep disorder |
| 04/24/2008 | US20080096931 fewer side effects; 2-keto-oxadiazole derivatives; 7-phenyl-1-[5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl]-heptan-1-one; treat anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders |
| 04/24/2008 | US20080096930 1-(2-hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-phenyl)-ethanone; 6-(3-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio)isonicotinic acid; 1-(2-hydroxy-4-{3-[4-(2H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-3-trifluoromethyl-phenyl)-ethanone; treatment of migriane |
| 04/24/2008 | US20080096929 enzyme myeloperoxidase inhibitor; 5-Phenoxymethyl-4-(dihydrofuran-2-one-3-yl)-2,4-dihydro-[1,2,4]triazole-3-thione; treatment or prophylaxis of neuroinflammatory disorders including multiple sclerosis, Alzheimer's disease, Parkinson's disease and stroke, COPD, asthma, inflammatory bowel disease |
| 04/24/2008 | US20080096928 Indole compounds that modify translational control of Hepatitis C virus |
| 04/24/2008 | US20080096927 Combination Therapy for Treating Cyclooxygenase-2 Mediated Diseases or Conditions in Patients at Risk of Thrombotic Cardiovascular Events |
| 04/24/2008 | US20080096926 Treatment Of Cognitive Impairment Using A Selective Dopamine D1 Receptor Agonist |
| 04/24/2008 | US20080096925 Analgesics for neuropathy, surgery, nervous system disorders, headaches, arthritis, psoriasis, respiratory system disorders, and gastrointestinal disorders; ethyl 4-phenyl-4-[1-(phenylmethyl)-1H-imidazol-2-yl]-1-piperidinecarboxylate; |
| 04/24/2008 | US20080096924 (2R) N-(1-benzylpiperidin-4-yl)-3-cyclohexylmethylthio-2-[(4R)-3-tert-butoxycarbonylthiazolidin-4-ylcarbonylamino]propanamide and hydroxypropyl methylcellulose acetate succinate or hydroxypropyl cellulose; N-type calcium channel blockers; analgesics; oral and nasal formulations; storage stability |
| 04/24/2008 | US20080096923 Determining the severity of retinopathy, neuropathy, and nephropathy; administering 8, 16, or 32 mg one to three times per day of ruboxistaurin, enzastaurin, PKC 412, candesartan cilexetil, fidarestat, lidorestat, pyridoxamine, pegaptanib, or ranibizumab |
| 04/24/2008 | US20080096922 N-{[cis-1-(3-methoxyphenyl)-4-(piperidin-4-ylamino)-cyclohexyl]methyl}sulfamide diHCL; tert-butyl [({[cis-4-[(biphenyl-4-ylmethyl)amino]-1-(3-methoxyphenyl)cyclohexyl]methyl}amino)sulfonyl]carbamate; for potentiating expression of low density lipoprotein recepotr; arteriosclerosis; hyperlipidemia |
| 04/24/2008 | US20080096921 Farnesoid x receptor agonists |
| 04/24/2008 | US20080096920 3-{4-[Bis-(quinolin-8-ylcarbamoylmethyl)-amino]-phenyl}-N-hydroxy-acrylamide; 4-(2-Hydroxycarbamoyl-vinyl)-N,N-bis-phenylcarbamoylmethyl-benzamide; useful in treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, and neurdegenerative disorders |
| 04/24/2008 | US20080096919 4-(2,2-dichloro)-N-(quinolin-3-yl)benzamide; (1R,2R)2-methyl-N-(quinolin-3-yl)-4-(2-(trifluoromethyl)cyclopropyl)benzamide; inflammation-related conditions in mammals, arthritis, Parkinson's/Alzheimer's diseases, stroke, asthma; acute/chronic or neuropathic pain; VR1 agonist/antagonist |
| 04/24/2008 | US20080096918 2-(3-(4-benzyloxybenzyl)-2-oxoimidazolidin-1-yl)-N-hydroxy-3-methylbutyramide; N-hydroxy-3-methyl-2-{2-oxo-3-(4-(pyridin-4-ylmethoxy)benzyl)imidazolidin-1-yl}butyramide with trifluoroacetic acid ; osteoarthrosis and rheumatoid arthritis; TNF- alpha converting enzyme (TACE) inhibitor |
| 04/24/2008 | US20080096917 for plants; 2-(dibenzofuranyl-2-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; 2-(indanyl-5-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; 2-(3-phenylquinolinyl-6-oxy)-2-methylthio-N-(2-methylpent-3-yn-2-yl)acetamide; phytopathogenic fungi |
| 04/24/2008 | US20080096916 Drugs And Prodrugs Useful The Treatment Of Energy Balance In Ruminants |
| 04/24/2008 | US20080096915 Compositions for the treatment of metabolic disorders |
| 04/24/2008 | US20080096914 cell-cycle dependent apoptosis inducing activity; targeted cancer therapy; 3-Cyano-2-(3-pyridin-3-yl-propanoylamino)-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylic acid ethyl ester |
| 04/24/2008 | US20080096913 peroxisome proliferator-activated receptor agonists; congestive heart failure, atherosclerosis, arteriosclerosis, obesity, hyperlipidemia, hypoalphalipoproteinemia, Syndrome X, diabetes, insulin resistance; 3-[5-Methoxy-1-(3-methoxy-benzyl)-1H-indol-3-yl]-propionic acid |
| 04/24/2008 | US20080096912 Indole, azaindole and related heterocyclic pyrrolidine derivatives |
| 04/24/2008 | US20080096911 Biphenyl-2-ylcarbamic Acid 1-{9-[2-(4-Hydroxy-2-oxo-2,3-dihydrobenzothiazol-7-yl)-ethylamino]nonyl}piperidin-4-yl Ester Bis(trifluoroacetate) Salt; chronic obstructive pulmonary disease, asthma; bronchodilators |
| 04/24/2008 | US20080096910 Rapid release mini-tablets provide analgesia in laboratory animals |
| 04/24/2008 | US20080096909 Alzheimer's disease; alkoxy-, hydroxy-, alkylthio-, or mercapto-substituted naphtho[ab,ij]isoquinolinium compounds, as well as oxidation or autooxidation products; side effect reduction |
| 04/24/2008 | US20080096908 Nitrate derivatives of atorvastatin with improved pharmacological activity and enhanced tolerability; coronary syndromes, neurodegenerative disorders, and for reducing cholesterol levels; antiinflammatory, antithrombotic and antiplatelet activity; fluvastatin 4-(nitrooxy)butyl ester |
| 04/24/2008 | US20080096907 inhibitor of a mycobacteria thymidine monophosphate kinase (TMPK); mycobacteria is M. tuberculosis; leprosy; 5-Methyl-1-(4-bromo-benzyl)-1H-pyrimidine-2,4-dione from reaction of thymine with 4-bromo-benzylbromide; thymine or uracil derivatives |
| 04/24/2008 | US20080096906 good affinity to the trace amine associated receptors (TAARs), especially for TAAR1; (3-Chloro-phenyl)-(1H-imidazol-2-ylmethyl)-methyl-amine from 3-chloro-N-methylaniline and imidazole-2-carboxyaldehyde and reduction of the carbonyl to methylene |
| 04/24/2008 | US20080096905 efficient method that can independently optimize the substituents at C2 and C4; ease of use in the making of a combinatorial array; 4,6-substituted-2-methylsulfanyl-pyrimidine-5-carboxaldehyde is claimed intermediate |
| 04/24/2008 | US20080096904 Compositions and methods for treatment and prevention of insulin resistance |
| 04/24/2008 | US20080096903 inhibitors of disease-related target, Heat Shock Protein 90 (HSP90); antiproliferative; 2-chloro-5'-sulfamoyladenosine analogs; derivatives of adenine and other purines; Sulfamic Acid 2-[6-amino-2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-purin-9-yl]-ethyl ester |
| 04/24/2008 | US20080096902 By inhibiting prostaglandin or cyclooxygenase-2 production; indolequinazoline alkaloids rutaecarpine or evodiamine, and butylated hydroxytoluene; skin disorders: erythromelalgia, Raynaud's Disease |
| 04/24/2008 | US20080096901 Aminotriazole compounds useful as inhibitors of protein kinases |
| 04/24/2008 | US20080096900 and coronary, inflammation, thrombosis; anticholesterol agent modifies LCAT polypeptide, Lecithin-cholesterol acyltransferase; wherein the cysteine residue is modified by replacing the thiol hydrogen with 3-pyrazinyl-2-carbonitrile; 3-(5-(methylthio)-1,3,4-thiadiazol-2-ylthio)pyrazine-2-carbonitrile |
| 04/24/2008 | US20080096899 N-Phenyl-2-Pyrimidine-Amine Derivatives and Process for the Preparation Thereof |
| 04/24/2008 | US20080096898 Organic Compounds |
| 04/24/2008 | US20080096897 water soluble; lower toxicity by photosensitization; anticancer; antitumor; antiinflammatory; arthritis; osteoporosis; ocular abnormal angiogenesis; multiple sclerosis, asthma, atherosclerosis |
| 04/24/2008 | US20080096896 Cyclic Amide & Ester Pyrazinoylganidine Sodium Channel Blockers |
| 04/24/2008 | US20080096895 Heterocyclic Derivatives and Their Use as Stearoyl-Coa Desaturase Inhibitors |
| 04/24/2008 | US20080096894 Anti-Bacterial Compounds |
| 04/24/2008 | US20080096893 Tablets containing 0.1 mg to 0.4 mg aminopterin in increments of 0.05 mg; uninterrupted dosage cycles as an antiinflammatory agent; nontoxic; side effect reduction |
| 04/24/2008 | US20080096892 C-Kit Modulators And Methods Of Use |
| 04/24/2008 | US20080096891 Triazine derivatives, their preparation and therapeutic application thereof |
| 04/24/2008 | US20080096890 Highly Selective Norepinephrine Reuptake Inhibitors and Methods of Using the Same |
| 04/24/2008 | US20080096889 Histone Deacetylases Inhibitors |
| 04/24/2008 | US20080096888 Novel compounds as opioid receptor modulators |
| 04/24/2008 | US20080096887 Benzene, Pyridine, and Pyridazine Derivatives |
| 04/24/2008 | US20080096886 amidation of 3-(benzyloxy)-1-cyclopropyl-6-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid via the 2-acid chloride and then reaction with an amine; hydrolysis or catalytic hydrogenation to deprotect 3-hydroxy group; high yields for industrial application; the 3-(benzyloxy)-2-carboxamide intermediate |
| 04/24/2008 | US20080096885 Methyl 1-(2-fluorophenyl)-2-[(3-methoxy-2-phenylquinolin-4-yl)carbonyl]hydrazinecarboxylate; schizophrenia |
| 04/24/2008 | US20080096884 phosphodiesterase inhibitors; inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis or allergic rhinitis |
| 04/24/2008 | US20080096883 Trifluoromethyl substituted benzamides as kinase inhibitors |
| 04/24/2008 | US20080096882 PDE4 (Phosphodiesterase) inhibitors; respiratory diseases, gastrointestinal diseases, inflammation the joints, skin or eyes, cancers, or diseases of the peripheral or central nervous system |
| 04/24/2008 | US20080096881 Quinazoline Derivatives |
| 04/24/2008 | US20080096880 Use of imidazo[1,2,4]triazinones which are inhibitors of cGMP-metabolizing phosphodiesterases (PDE I, II and V) to treat cardiovascular disorders, urogenital disorders, prostate hyperplasia, ocular disorders such as glaucoma, optic neuropathy, diabetic gastroparesis, dementia |
| 04/24/2008 | US20080096879 More potent analogs of FR901464 from Pseudomonas sp. No. 2663 culture and chemical synthesis; anticancer agents; intermediates |
| 04/24/2008 | US20080096878 CGRP (Calcitonin Gene-Related Peptide); migraine and cluster headaches; 2-(5-Bromo-1'1'-dioxido-2-oxo-2',3',5',6'-tetrahydrospiro[indole-3,4'-thiopyran]-1 (2H)-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)acetamide for example; use with other drugs |
| 04/24/2008 | US20080096877 Glucokinase activators; prophylaxis or treatment of diabetes, obesity; sulfonamide or sulfonate-functional thiazole or thiadiazole-substituted indoles; N,N-dimethyl-2-{4-[(2-{7-[methyl(2-thienylsulfonyl)amino]-1H-indol-2-yl}-1,3-thiazol-5-yl)methyl]piperazin-1-yl}acetamide for example |