| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
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| 07/24/2008 | US20080176900 small molecule, low toxicity, high efficiency, high economic value; 5-(2,6-dioxopiperidin-3-yl)-5H-thieno(3,4-c)pyrrole-4,6-dione: |
| 07/24/2008 | US20080176899 Such as 1-Benzo[1,3]dioxol-5-yl-cyclopropanecarboxylic acid [5-(2-methoxy-pyridin-3-ylmethyl)-thiazol-2-yl]-amide 5-(2-Methoxy-pyridin-3-ylmethyl)-thiazol-2-ylamine; cystic fibrosis transmembrane conductance regulator disorders |
| 07/24/2008 | US20080176898 Leukotriene antagonists; cardiovascular disorders like unstable angina pectoris or myocardial infarction; Methyl 1-{[5-(ethoxycarbonyl)-2-(3-{4-[(4-isopropoxybenzyl)oxy]phenyl}propoxy)phenyl]-acetyl}piperidine-4-carboxylate |
| 07/24/2008 | US20080176897 Substituted Quinolone Carboxylic Acids, Their Derivatives, Site of Action, And Uses Thereof |
| 07/24/2008 | US20080176896 Modulators of cellular adhesion |
| 07/24/2008 | US20080176895 Gastrointestinal disorders; selectivity, potency, pharmacokinetics, duration of action; minimal side effects |
| 07/24/2008 | US20080176894 Used as nitric oxide synthase inhibitors; treating acute inflammatory disease with such as 2-[2-(2-amino-4-methylpyridin-6-yl)ethyl]-3H-imidazo[4,5-b]pyridine |
| 07/24/2008 | US20080176893 Formulation of a Thienopyridine Platelet Aggregation Inhibitor |
| 07/24/2008 | US20080176892 Novel Azaheterocyclic Compounds as Kinase Inhibitors |
| 07/24/2008 | US20080176891 N-(2-Aminoethyl)-4-(2-ethyl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzene-sulfonamide; respiratory disorders; rheumatoid arthritis |
| 07/24/2008 | US20080176890 Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| 07/24/2008 | US20080176889 4-{2-[Bis-(2-chloroethyl)amino]ethoxy}-10H-acridine-9-one; Anticancer agents |
| 07/24/2008 | US20080176888 Sirolimus Formulation |
| 07/24/2008 | US20080176887 Method for Decreasing Nicotine and Other Substance Use in Humans |
| 07/24/2008 | US20080176886 Phenanthroindolizidine Alkaloids |
| 07/24/2008 | US20080176885 Improved Pharmacokinetics; side effects reduction; codrugs are covalently bound by a linker that is capable of cleavage in the body; analgesics |
| 07/24/2008 | US20080176884 7,8-Saturated-4,5-Epoxy-Morphinanium Analogs |
| 07/24/2008 | US20080176883 Aminopyrrolidines as chemokine receptor antagonists |
| 07/24/2008 | US20080176882 Salts of 3-(3-amino-2-(r)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one |
| 07/24/2008 | US20080176881 Compounds and compositions as protein kinase inhibitors |
| 07/24/2008 | US20080176880 Activity against strains having acquired resistance nonnucleoside reverse transcriptase inhibitors; human alpha1 acid glycoprotein nonbinding; such as 4-[[(5-bromo-4,6-dichloro)-2-pyrimidinyl]amino]-benzonitrile |
| 07/24/2008 | US20080176879 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide; for the treatment of allergies and/or systemic matocytosis associated with FIP1L1-PDGFR alpha -gene fusion; platelet derived growth factor alpha inhibitors |
| 07/24/2008 | US20080176878 Crystalline rosuvastatin calcium |
| 07/24/2008 | US20080176877 platelet lowering agent anagrelide especially 3-and 5-substituted analogues, with reduced potential for cardiovascular side-effects; imidazo[2,1-b]quinazolin-2-one derivatives; by inhibiting megakaryocytopoeisis; antiproliferative agents |
| 07/24/2008 | US20080176876 Substituted 2-Alkyl Quinazolinone Derivatives as Parp Inhibitors |
| 07/24/2008 | US20080176875 Substituted quinazolines |
| 07/24/2008 | US20080176874 Derivatives of Pyrido[2,3-d]pyrimidine, the Preparation Thereof, and the Therapeutic Application of the Same |
| 07/24/2008 | US20080176873 Novel Pharmaceutical Compositions for Treating Acquired Chronic Pain and Associated Dysphoria |
| 07/24/2008 | US20080176872 Chemical Compounds |
| 07/24/2008 | US20080176871 4-cyanophenylamino-substituted bicyclic heterocyclic compounds as hiv inhibitors |
| 07/24/2008 | US20080176870 Heterobicyclic metalloprotease inhibitors |
| 07/24/2008 | US20080176869 e.g. N-(4-fluorobenzyl)-3-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-2-carboxamide; viricide in combination with other HIV/AIDS antivirals, immunomodulators, antibiotics or vaccines; AIDS |
| 07/24/2008 | US20080176868 Preparation and use of compounds as protease inhibitors |
| 07/24/2008 | US20080176867 e.g., N-[[5-(4-bromophenyl)-4-(2,4-dichlorophenyl)pyrimidin-2-yl]methyl]-3-(trifluoromethyl)benzenesulfonamide; cannabinoid receptor modulator; metabolic and gastrointenstinal disorders, antidiabetic, antiinflammatory, analgesic agent; neurodegenerative diseases |
| 07/24/2008 | US20080176866 3-(5-Bromo-2-{4-[5-bromo-4-((1R,2R)-2-hydroxy-1-methyl propylamino)-pyrimidin-2-ylamino]phenylamino}pyrimidin-4-ylamino)butan-2-ol; cell cycle and tyrosine kinase receptor inhibitor; antiproliferative, anticarcinogenic agent |
| 07/24/2008 | US20080176865 Substituted arylpyrazoles |
| 07/24/2008 | US20080176864 [4-(3-Methoxy-phenyl)-4-oxo-butyl]-carbamic acid tert-butyl ester; Age related functional decline, osteoporosis, osteopenia, bone fractures, male and female sexual dysfunction, erectile dysfunction, depression, prostate cancer, decreased cognitive ability, or lethargy |
| 07/24/2008 | US20080176863 Capped pyrazinoylguanidine sodium channel blockers |
| 07/24/2008 | US20080176862 New Compounds 617 |
| 07/24/2008 | US20080176861 Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis |
| 07/24/2008 | US20080176860 8-[4-{4-[5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-4-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-carbonyloxy)-piperidin-1-yl]-1-cyclopropyl-7-fluoro-9-methyl; microbioside; multi-drug resistant bacteria; bacterial topoisomerases and protein synthesis inhibitor |
| 07/24/2008 | US20080176859 Heterocyclyamide-substituted imidazoles |
| 07/24/2008 | US20080176858 Selective antagonists of a2a adenosine receptors |
| 07/24/2008 | US20080176857 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors |
| 07/24/2008 | US20080176856 Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors |
| 07/24/2008 | US20080176855 drugs such as 5-(6-Chloropyridazin-3-yl)-1-azabicyclo[3.2.1]octane, used for treatment or prevention of disorders related to a nicotinic receptor dysfunction |
| 07/24/2008 | US20080176854 Nitro-Substituted Phenyl-Piperazine Compounds, Their Preparation and Use in Medicaments |
| 07/24/2008 | US20080176853 Triazine derivatives and their therapeutical applications |
| 07/24/2008 | US20080176852 Biguanide and dihydrotriazine derivatives |
| 07/24/2008 | US20080176851 by blocking sGC.alpha.1.beta.1 signaling; applying sGC inhibitor such as NS-2028 (4H-8-Bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one) on skin; inhibitor of Soluble Guanylate Cyclase (sGC), a receptor for NO; preventing Nitric oxide-induced lymphatic endothelial cell proliferation |
| 07/24/2008 | US20080176850 able to inhibit various mutated RTs, including K103N, Y181C and Y188L |
| 07/24/2008 | US20080176849 e.g. N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]-amino]methyl]phenyl]-2E-2-propenamide; histone deacetylase inhibitor; anticarcinogenic, antitumor, antiproliferative agents; improved stability |
| 07/24/2008 | US20080176848 e.g. N-Hydroxy-3-{1-[4-(1-methyl-1H-indol-5-yl)-benzenesulfonyl]-1H-pyrrol-3-yl}-acrylamide; antiproliferative, anticarcinogenic, antiinflammatory, neuroleptic agent, autoimmune disorders |
| 07/24/2008 | US20080176847 Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors |
| 07/24/2008 | US20080176846 e.g. 3-(5-amino-2-methylphenyl)-7-chloro-1-methyl-1,6-naphthyridin-2(1H)-one; protein kinase inhibitor; antiinflammatory, anticarcinogenic, antiallergen, antidiabetic, antiischemic, hypotensive agent |
| 07/24/2008 | US20080176845 Antagonists of A2B adenosine receptors for treatment of inflammatory bowel disease |
| 07/24/2008 | US20080176844 Pharmacokinetically Improved Compounds |
| 07/24/2008 | US20080176843 Modulators of muscarinic receptors |
| 07/24/2008 | US20080176842 N1-[1-[N-(2-methylpropyl)-N-(phenylsulfonyl)amino]-2R-hydroxy-3S-(phenylmethyl)prop-3-yl]-3-(1-morpholinosulfonyl)-2R-methylpropionamide; viricide; human T-cell leukemia/limphoma virus |
| 07/24/2008 | US20080176841 (amidomethyl-amido)-(carboxy/amido)epoxide derivatives; cathepsin inhibitor; antiinflammatory, anticarcinogenic, antidiabeticagent, antiallergen, autoimmune and neurodegenerative disorders |
| 07/24/2008 | US20080176840 e.g. 4-(4-(6-(N-(2-methoxyethyl)-N-methylamino)pyridin-3-yl)-5-hydroxy-4H-1,2,4-triazol-3-yl)-6-isopropylbenzene-1,3-diol; Heat Shock Protein 90 (HSP90) modulator; antiproliferative, anticarcinogenic, antiinflammatory agent; angiogenesis inhibition, infections |
| 07/24/2008 | US20080176839 e.g. N-benzyl-2-(3,4-dichlorophenyl)-4-(6-fluoro-2-oxo-1,2-dihydro-1'H-spiro[3,1-benzoxazine-4,4'-piperidin]-1'-yl)-N-methylbutanamide; neurokinin 3 receptor antagonist; antidepressant, anxiolytic agent, analgesic; psychosis, Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder |
| 07/24/2008 | US20080176838 e.g. [3-[(Cyclopropanecarbonyl-amino)-methyl]-pyrrolidin-1-yl}-(2-fluoro-benzyl)-propyl]-carbamic acid tert-butyl ester; dipeptidyl-peptidase inhibitor; antidiabetic, hypoglycemic agent; metabolic disorders, obesity, non-insulin dependent diabetes; |
| 07/24/2008 | US20080176837 Treatment of Pain |
| 07/24/2008 | US20080176836 Use of selected CGRP antagonists for combating menopausal hot flushes |
| 07/24/2008 | US20080176835 Prenyl Transferase Inhibitors |
| 07/24/2008 | US20080176834 Quinolone Carboxylic Acids, Derivatives Thereof, and Methods of Making and Using Same |
| 07/24/2008 | US20080176833 Dihydropyridine derivatives as useful as protein kinase inhibitors |
| 07/24/2008 | US20080176832 Pyrazolo [3,4-D]Azepine Derivatives as Histamine H3 Antagonists |
| 07/24/2008 | US20080176830 Compounds, Compositions, and Methods |
| 07/24/2008 | US20080176829 e.g. 2,5-methylene-9-(phenylsulfonyl)-1,2,3,4,5,9-hexahydro[1,5]oxazocino[3,2-e]indole; serotonin receptors antagonist or partial agonist; metabolic diseases, e.g. obesity, insulin resisitance, type 2 diabetes, eating disorders; antidepressant, anxiolytic agent; cosmetics |
| 07/24/2008 | US20080176828 anticarcinogenic agent, synergistic with microtubulin stabilizers, other anticancer agents, vaccines, immunotherapy |
| 07/24/2008 | US20080176827 e.g. ethyl 6-(3-{2-[(benzylsulfonyl)amino]-2-oxoethyl}pyrrolidin-1-yl)-5-cyano-2-methylnicotinate; P2Y12 (G-protein coupled receptor) antagonist and anti-trombotic agent; high potency and selectivity; cardiovascular disorders, platelet aggregation disorder, acute thrombotic occlusion |
| 07/24/2008 | US20080176825 Oral Neurotherapeutic Cefazolin Compositons |
| 07/24/2008 | US20080176824 Pharmaceutical Compositions 3 |
| 07/24/2008 | US20080176823 androgen receptor modulator; analogs of androst-5-ene-3 beta ,17 beta -diol ("AED") or 1,3,5(10)-estratriene-17 alpha -ethynyl-3 beta ,17 beta -diol ("EED") |
| 07/24/2008 | US20080176822 Novel composition for treating metabolic syndrome |
| 07/24/2008 | US20080176821 phosphoryl-di(glutamate dibenzylester or dihydroxyamide) derivatives; neuroleptic agent, neurodegenerative diseases, neuropathic pain, epilepsy, ischaemia, schizophrenia, amyotrophic lateral sclerosis, Alzheimer's, Parkinson, Huntington diseases; |
| 07/24/2008 | US20080176820 Use of L-alpha-lysophosphatidylcholine to obtain the differentiation of monocytes into mature dendritic cells in vitro |
| 07/24/2008 | US20080176819 with a water-insoluble cellulose derivative such as ethyl cellulose; cardiovascular disease or Type II diabetes |
| 07/24/2008 | US20080176818 Sulfoglycolipid Antigens, Their Extraction From Mycobacterium Tuberculosis, and Their Use Against Tuberculosis |
| 07/24/2008 | US20080176817 the nucleoside 2',3'-dideoxy-3'-hydroxymethylcytidine or a prodrug; reverse transcriptase of the HIV bears a mutation that allows an obligate chain terminating nucleoside- or nucleotide phosphate to be excised from the nascent DNA strand by ATP- or pyrophosphate; also with a NRTI |
| 07/24/2008 | US20080176816 Method of making and using an adenosine analogue |
| 07/24/2008 | US20080176815 Compounds that interact with kinases |
| 07/24/2008 | US20080176814 nonpeptidic inhibitors of cathepsin G; genetic diseases, degenerative diseases, DNA damages, neoplasia and/or skin diseases; DNA or polynucleotide sequences having a chain length of at least 60 nucleotides and being substantially not subjected to undergo efficient base pairing |
| 07/24/2008 | US20080176813 Carbocyclic nucleosides and process for obtaining such |
| 07/24/2008 | US20080176812 Allele-specific silencing of disease genes |
| 07/24/2008 | US20080176811 esterification of naringin with a polyunsaturated fatty acid with hydrolase enzyme; lightening skin; antiaging |
| 07/24/2008 | US20080176810 Use of 3, 4', 5-Trihydroxy-Stilbene-3-Beta-D-glucoside in Prepartion of Medicines For Treating and/or Preventing Ischemic Heart Disease |
| 07/24/2008 | US20080176809 Use of D-ribose to treat cardiac arrhythmias |
| 07/24/2008 | US20080176807 Facially amphiphilic polymers and oligomers and uses thereof |
| 07/24/2008 | US20080176805 Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| 07/24/2008 | US20080176800 Methods for the delivery of bioactive substances with biodegradable polyphosphates |
| 07/24/2008 | US20080176798 Compounds and methods for diagnosis and immunotherapy of tuberculosis |
| 07/24/2008 | US20080176796 screening for selective antagonists or agonists of tumor necrosis factor receptors, used as antiinflammatory or antiischemic agents; treatment of cardiovascular and kidney diseases |
| 07/24/2008 | US20080176793 Upregulating activity or expression of bdnf to mitigate cognitive impairment in asymptomatic huntington's subjects |
| 07/24/2008 | US20080176747 3,4-diaminopyridine derivatives |
| 07/24/2008 | US20080176309 Inhibition of Shp2/PTPN11 Protein Tyrosine Phosphatase by NSC-87877, NSC-117199 and Their Analogs |
| 07/24/2008 | US20080176308 Of tetrahydroacridines and tetrahydroquinolinones which are acetylcholinesterase inhibitors and N-methyl-D-aspartate (NMDA) receptor antagonists; cognitive defects; Alzheimer's disease; Parkinson's disease |
| 07/24/2008 | US20080175932 Method for Decreasing Nicotine and Other Substance Use in Humans |