| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
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| 08/07/2008 | US20080188546 Preventive or therapeutic agents for decubitus |
| 08/07/2008 | US20080188545 (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride monohydrate; cardiovascular disease; osteoporosis; inflammation of airway epithelium; disorders of alveolar tissue; bladder incontinence; impaired hearing; endothelial lesions |
| 08/07/2008 | US20080188544 Lyophilized formulations of salinosporamide a |
| 08/07/2008 | US20080188543 {1-Methyl-6-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid; deep vein thrombosis and coronary heart disease, Alzheimer's disease and pulmonary fibrosis |
| 08/07/2008 | US20080188542 Novel indole polymorphs |
| 08/07/2008 | US20080188541 Combined with ascorbic acid, creatine and melatonin; inhibiting cancer and/or tumor cellular proliferation without toxic effect |
| 08/07/2008 | US20080188540 Pharmaceutical compositions containing substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1) |
| 08/07/2008 | US20080188539 Ramipril-amino acid salts |
| 08/07/2008 | US20080188538 Administering rampiril; dysglycemia, where the patient has no history of cardiovascular disease |
| 08/07/2008 | US20080188537 Method of treating bipolar depression with a benzamide derivative |
| 08/07/2008 | US20080188536 2-thiophenecarboxylic acid-5-nitro-2-(2-thienylcarbonyl)hydrazide; antibacterial agent; inhibition of formation of biofilms in personal hygiene articles, toileteries, cosmetics and in industrial setting; bacterial damage or disease; Pseudomonas aeruginosa or Burkholderia cepacia |
| 08/07/2008 | US20080188535 2-thiophenecarboxylic acid-5-nitro-2-(2-thienylcarbonyl)hydrazide; antibacterial agent; inhibition of formation of biofilms in personal hygiene articles, toileteries, cosmetics and in industrial setting; bacterial damage or disease; Pseudomonas aeruginosa or Burkholderia cepacia |
| 08/07/2008 | US20080188533 Dual-acting antihypertensive agents |
| 08/07/2008 | US20080188532 Indole Compound and Use Thereof |
| 08/07/2008 | US20080188531 Ethyl 2'-(acetylamino)-4'-methyl-4,5'-bi-1,3-thiazole-2-carboxylate; autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial, viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries |
| 08/07/2008 | US20080188529 N1-(cyanomethyl)-N2-(2,2,2-trifluoro-1-phenylethyl)-L-leucinamide; antiarthritic agent; osteoporosis and other bone loss disorders |
| 08/07/2008 | US20080188528 Modulators of C3a receptor and methods of use thereof |
| 08/07/2008 | US20080188527 Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer |
| 08/07/2008 | US20080188526 Pharmaceutical composition comprising, in combination, saredutant and escitalopram |
| 08/07/2008 | US20080188525 Rolipram or methylphenyl substituted rolipram; Cognitive dysfunction; administering a (PDE4) inhibitor in the absence of formal cognitive training |
| 08/07/2008 | US20080188524 Administering a cyclin-dependent kinase (CDK) inhibitor; for example, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl)methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide |
| 08/07/2008 | US20080188523 S)-(-)-N-[4-(4-acetamido-4-phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide; significantly enhancing the pharmacological effects of each of the compounds used alone, in particular the antidepressant effects |
| 08/07/2008 | US20080188522 4-Methylpropiophenone reacted with piperidine hydrochloride and 1,3-dioxolane in the presence of an acid catalyst, and the tolperisone obtained in the form of an acid addition salt is separated by filtering after the reaction mixture has cooled down; improved purity, simplification |
| 08/07/2008 | US20080188521 Novel pharmaceutical compounds |
| 08/07/2008 | US20080188520 e.g. 1-(2-Cyclopropylmethoxy-1,2-diphenylethyl)-1H-pyridin-2-one; potassium (K+) channel-blocking agent; potassium channel KACh and TASK-1 channel blocking agent; atrial arrhythmias, atrial fibrillation or atrial flutter; respiratory disorders, neurodegenerative disorders; anticarcinogenic agent |
| 08/07/2008 | US20080188519 Novel azacyclic ethynyl derivatives |
| 08/07/2008 | US20080188518 5-Substituted Imidazoles |
| 08/07/2008 | US20080188517 Crystalline forms of a factor xa inhibitor |
| 08/07/2008 | US20080188516 Imiadazo[4,5-c] pyridine compound and method of antiviral treatment |
| 08/07/2008 | US20080188515 metalloproteinases inhibitor, particular Peptide Deformylase (Pdf) inhibitor; antibiotic; e.g. 2-(6-fluoro-imidazo[1,2-a]pyridin-3-ylamino)-N-hydroxy-acetamide |
| 08/07/2008 | US20080188514 e.g. 5-(3-methoxybenzyloxy)-1H-pyrrolo[2,3-b]pyridine; protein kinases inhibitor; central nervous system disorders; Alzheimer's disease; Parkinson's disease; anticancer, antitumor agents; analgesics; cogestive heart failure; skin disorders; inflammatory bowel disorders; transplant rejection |
| 08/07/2008 | US20080188513 Good aqueous solubility and good physical and chemical stability in solid form; chemical intermediates |
| 08/07/2008 | US20080188512 Administering N-(1H-tetrazol-5-yl)-1-phenoxy-4H-quinolizin-4-one-3-carboxamide; concomitant use of serotonin 5-HT3 receptor antagonists |
| 08/07/2008 | US20080188511 Rapamycin; the 40-hydroxy position is derivatised as a carboxylic acid ester, as an ether, as a phosphate ester, as a phosphinate ester, as an acetal or as a gycosyl; transplantation rejection, graft vs. host disease, autoimmune disorders, inflammation, vascular, fibrotic diseases |
| 08/07/2008 | US20080188510 Novel methods using zonisamide |
| 08/07/2008 | US20080188509 Transdermal Preparations and Method for Relieving Side Effects in Pergolide Therapy |
| 08/07/2008 | US20080188508 Methods and Therapies for Potentiating a Therapeutic Action of an Opioid Receptor Agonist and Inhibiting and/or Reversing Tolerance to Opioid Receptor Agonists |
| 08/07/2008 | US20080188507 3-(3-biphenylyl)-5-[3-oxospiro[6-azaisobenzofuran-1(3H),4'-piperidin]-1'-yl]-1H-pyrazole; neuropeptide Y receptor antagonists; metabolic, genitalor reproductive, gastro-intestinal, respiratory system disorders, antiinflammatory agent or glaucoma; cyclization |
| 08/07/2008 | US20080188506 6-chloro-2'-(3-chlorophenyl)-4'-(2,2-dimethylpropyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione; mdm2 antagonists; have effects in p53 mutant cells by mdm2-p53 feedback control loop; anticarcinogenic agent; |
| 08/07/2008 | US20080188505 Applying agmatine and a dermatologically acceptable carrier to the skin; inhibiting hair growth |
| 08/07/2008 | US20080188504 Process for Preparing Pure Amorphous Rosuvastatin Calcuim |
| 08/07/2008 | US20080188503 New Compounds II |
| 08/07/2008 | US20080188502 New Compounds I |
| 08/07/2008 | US20080188501 retrovirus inhibor; anticarcinogenic, antidiabetic agent, immunosuppressant, autoimmune diseases; 2-{6-[3(R)-Amino-piperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl}-4-fluoro-benzonitrile; type 2 diabetes mellitus, impaired glucose tolerance, obesity, multiple sclerosis |
| 08/07/2008 | US20080188500 e.g. N-[4-methyl-3-(9H-pyrimido[4,5-b]indol-7-yl)phenyl]-3-(trifluoromethyl)benzamide; Janus kinases inhibitor; anticarcinogenic agent; immune-related diseases, skin disorders, myeloid proliferative disorders |
| 08/07/2008 | US20080188499 catecholpyrazine analogs, e.g. 2-[2-(5-nitro-2-furyl)vinyl]-4-[2-(3,4-dihydroxyphenyl)ethylamino]quinazoline; inhibitors of bacterial lipid A biosynthesis; antibiotic and bactericide; sterilization agent and antiseptic |
| 08/07/2008 | US20080188498 Pyridopyrimidinone compounds with antimalarial activity |
| 08/07/2008 | US20080188497 Combination regime; preventing stroke or reducing the risk of stroke or secondary stroke |
| 08/07/2008 | US20080188496 3-(Dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxybenzenesulfonamide derivatives and methods of use |
| 08/07/2008 | US20080188495 e.g. 6-[(1E)-2-(3,4-dimethoxyphenyl)vinyl]-3-ethyl-1,5-dimethyl-1,3-dihydrothiopheno[2,3-d]pyrimidine-2,4-dione; neurodegenerative disorders, antiischemic agent, antidepressant, attention deficit disorder, hepatic fibrosis, cirrhosis of the liver, and drug addiction |
| 08/07/2008 | US20080188492 Organic Compounds |
| 08/07/2008 | US20080188491 Modulation of pathogenicity |
| 08/07/2008 | US20080188490 e.g. 1-(3-Chloro-phenylethynyl)-3-(3,4-difluoro-phenylamino)-cyclohexanol; metabotropic glutamate receptors modulator/antagonist; |
| 08/07/2008 | US20080188489 Cell differentiation inducer |
| 08/07/2008 | US20080188488 Heterocyclic Derivatives and Their Use as Stearoyl-Coa Desaturase Inhibitors |
| 08/07/2008 | US20080188487 5-amido-(1h-indol-2-yl)-piperazin-1-yl-methanone derivatives |
| 08/07/2008 | US20080188486 e.g. (1-cyclopentylmethyl-1H-indol-5-yl)-(4-isopropyl-piperazin-1-yl)-methanone; antagonists and/or inverse agonists at the histamine 3 receptor; antidepressant, anxiolytic agent; obesity, cardiovascular disorders |
| 08/07/2008 | US20080188485 4-piperazine-4-piperidine-1-ketone derivatives; graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis; human immunodeficiency viricides |
| 08/07/2008 | US20080188484 Indol-2-yl-piperazin-1-yl-methanone derivatives |
| 08/07/2008 | US20080188483 Compounds and Compositions as Protein Kinase Inhibitors |
| 08/07/2008 | US20080188482 [1H-Pyrazolo[3, 4-D]Pyrimidin-4-Yl]-Piperidine or -Piperazine Compounds as Serine-Theoronine Kinase Modulators (P70s6k, Atk1 and Atk2) for the Treatment of Immunological, Inflammatory and Proliferative Diseases |
| 08/07/2008 | US20080188481 e.g. 1-[4-(1-Phenyl-1-(pyrazinyl)-methylene)-piperidin-1-yl]-2-(4-methoxy-7-pyrazinyl-6-azaindol-3-yl)-ethane-1,2-dione; viricides for prophylaxis of lympadenopathy associated virus; synergystic mixtures with immunomodulators |
| 08/07/2008 | US20080188480 Use of Sildenafil, Vardenafil and Other 5-Phosphodiesterase Inhibitors to Enhance Permeability of the Abnormal Blood-Brain Barrier |
| 08/07/2008 | US20080188479 Methods to Treat Cancer with 10-propargyl-10-deazaaminopterin and Methods for Assessing Cancer for Increased Sensitivity to 10-propargyl-10-deazaaminopterin |
| 08/07/2008 | US20080188478 Compounds Useful In Therapy |
| 08/07/2008 | US20080188477 Substituted heterocycles, their use as medicament, and pharmaceutical preparations comprising them |
| 08/07/2008 | US20080188476 Comprises zonisamide (anticonvulsant) in combination with bupropion for enhancing activity of norepinephrine and/or dopamine via uptake inhibition; side effect reduction |
| 08/07/2008 | US20080188475 Perhydro- or hydrophenanthrene derivatives; antiinflammatory, analgesic, anticarcinogenic, and antitumor agents; autoimmune, skin, cardiovascular, and viral diseases |
| 08/07/2008 | US20080188474 Substituted triazoles useful as axl inhibitors |
| 08/07/2008 | US20080188473 Indoles Useful in the Treatment of Inflammation |
| 08/07/2008 | US20080188472 Indole-2-Carboxylic Acid Hydrazides |
| 08/07/2008 | US20080188471 Dipeptidyl Peptidase-IV Inhibiting Compounds, Method Of Preparing The Same, And Pharmaceutical Compositions Containing The Same As An Active Agent |
| 08/07/2008 | US20080188470 Oxazolidinone Derivatives as Antimicrobials |
| 08/07/2008 | US20080188469 Vaccination |
| 08/07/2008 | US20080188467 Compounds for the prevention and treatment of cardiovascular diseases |
| 08/07/2008 | US20080188466 Antiviral agent especially to treat hepatitis C virus infections; 5-Hydroxy-4-(7-methoxy-1,1-dioxo-1,2-dihydro-1 lambda 6-benzo[1,2,4]thiadiazin-3-yl)-2-(3-methyl-butyl)-6-thiophen-2-yl-2H-py-ridazin-3-one; side effects reduction |
| 08/07/2008 | US20080188465 Stable pure anhydrous polymorphic Form I, free of other polymorphs and solvating agents such as water and organic solvents; anti-psychotic agent |
| 08/07/2008 | US20080188464 Combinations of Dopamine D2 Receptor Blockade with Norepinephrine Reuptake Inhibition and With Norepinephrine Alpha 2 Receptor Blockade |
| 08/07/2008 | US20080188463 6-oxo-6,7-dihydro-5h-dibenzo[b,d]azepin-7-yl derivatives |
| 08/07/2008 | US20080188462 reversed chloroquines; to treat chloroquine resistant/sensitive malaria parasites; N'-(7-Chloro-quinolin-4-yl)-N-[3-(10,11-dihydro-dibenzo[b,f]azepin-5-yl)-propyl]-N-methyl-propane-1,3-diamine |
| 08/07/2008 | US20080188461 Compositions and methods for detecting, preventing and treating seizures and seizure related disorders |
| 08/07/2008 | US20080188460 Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them |
| 08/07/2008 | US20080188459 antiinflammatory agents; side effects rduction; less toxicity, irritation, allergic response; rheumatoid arthritis, psoriasis, asthma, Crohn's disease, ulcerative colitis, COPD ; rel-N-[(2R,10,14b)-8-cyano-1,2,3,4,10,14b-hexahydro-10-methyldibenzo[c,f]pyrido[1,2-a]azepin-2-yl]-2,2,2-trifluoroacetamide |
| 08/07/2008 | US20080188458 Enzyme inhibitors; interferons; interleukins; cyclosporins; Cycloprop[d]indolo[2,1-a][2]benzazepine/indolo[2,1-a][2]benzazepine derivatives; N'-(5-((sec-Butylsulfonyl)carbamoyl)-8-cyclohexyl-11-methoxy-1,12b-dihydrocyclopropa[d]indolo[2,1-a][2]benzazepin-1a(2H)-yl)-N,N-dimethylethanediamide |
| 08/07/2008 | US20080188457 Modulation of Neurogenesis with Biguanides and GSK3-beta Agents |
| 08/07/2008 | US20080188455 angiogenesis and/or cell proliferation, carcinoma, myeloid leukemia, endometriosis; inhibitors of the receptor protein tyrosine kinase; N3-(3-cyclopentyl-1,2,3,4,5,6-hexahydrobenzo[d]azocin-8-yl)-1-(6-fluoroquinazolin-4-yl)-1H-1,2,4-triazole-3,5-diamine |
| 08/07/2008 | US20080188454 angiogenesis and/or cell proliferation, carcinoma, myeloid leukemia, endometriosis; inhibitors of the receptor protein tyrosine kinase; N3-(3-cyclopentyl-1,2,3,4,5,6-hexahydrobenzo[d]azocin-8-yl)-1-(6-fluoroquinazolin-4-yl)-1H-1,2,4-triazole-3,5-diamine |
| 08/07/2008 | US20080188453 Mapk/erk kinase inhibitors |
| 08/07/2008 | US20080188452 Macrocyclic Benzofused Pyrimidine Derivatives |
| 08/07/2008 | US20080188451 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol1yl)-3-(trifluoromethyl)phenyl]benzamide or an N-oxide or salts; anticarcinogenic agent (leukaemia) |
| 08/07/2008 | US20080188450 Macrolactams by engineered biosynthesis |
| 08/07/2008 | US20080188449 Treatment of Conditions Caused By Calcium Abnormalities |
| 08/07/2008 | US20080188448 reduced antiglucocorticoid effects; side effect reduction; endometriosis, leiomyomas of the uterus, dysfunctional bleeding, dysmenorrhoea; antitumor agents; female fertility control, for hormone replacement therapy; 6-[2(2,2-Dimethylpropyl)-2-hydroxypent-3-ynoylamino]-4-methyl-2,3-benzoxazin-1-one |
| 08/07/2008 | US20080188447 Glucocorticoid-lowering composition |
| 08/07/2008 | US20080188446 [4S-(4 alpha ,4a alpha ,5a alpha ,12a alpha )]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamides stabilized in a base; and a second base; dermatological conditions, inflammatory acne vulgaris |
| 08/07/2008 | US20080188445 Tetracycline compositions for topical administration |
| 08/07/2008 | US20080188444 Improved lipophilicity, toxicity, bioavailability, and pharmacokinetics; for treatment of cardiovascular and neurological disorders; alzheimer's disease |
| 08/07/2008 | US20080188443 (4 beta S,7R,8 alpha R)-4 beta -benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-4b,5,6,7,8,8 alpha ,9,10-octahydrophenanthrene-2-carboxamide; modulators of the glucocorticoid receptor; asthma, dermatitis, inflammatory bowel disease, Alzheimer's disease, psychotic major depression |
| 08/07/2008 | US20080188441 Composition for Treating Inflammatory Diseases |
| 08/07/2008 | US20080188440 Beta-L-2'-Deoxy-Nucleosides for the Treatment of Hepatitis B |