Patents
Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912)
09/2008
09/04/2008US20080214562 Chemical Compounds
09/04/2008US20080214561 Amorphous, methylparaben cocrystal and other distinct crystalline forms; distinguished by infrared spectra, X ray powder diffraction patterns and glass transition temperatures neurodegenerative disfunction, pain, cognitive disorders
09/04/2008US20080214560 (4-{[5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl]amino}phenyl)(phenyl)methanone hydrochloride; glycogen synthase kinase-3 inhibitors
09/04/2008US20080214559 Compounds with a combination of cannabinoid cb1 antagonism and serotonin reuptake inhibition
09/04/2008US20080214558 2-[(2-(4-methylpyrazin-1-yl)-3-fluoro-5-pyridinyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; 2-[(4-(4-methylpyrazin-1-yl)-phenyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; colon, breast, stomach, urogenital, pancreatic cancers, leukemia lymphoma
09/04/2008US20080214557 Method for preparation of pharmaceutical composition having improved disintegratability and pharmaceutical composition manufactured by same method
09/04/2008US20080214556 Stabilizing with intravenous infusion followed by oral sustained release maintenance formulation; reducing blood plasma HbA1x levels
09/04/2008US20080214555 Aqueous intravenous solution containing dextrose and/or sodium chloride; rapid delivery, low viscosity; free of propylene glycol and/or polyethylene glycol
09/04/2008US20080214554 Methods for preventing or treating cardiac arrhythmia
09/04/2008US20080214553 2-(4-Oxo-4H-Quinazolin-3-Yl) Acetamides and Their Use as Vasopressin V3 Antagonists
09/04/2008US20080214551 Treatment of Burns
09/04/2008US20080214550 Novel inhibitors of folic acid-dependent enzymes
09/04/2008US20080214549 N-Substituted Glycine Derivatives: Hydroxylase Inhibitors
09/04/2008US20080214548 2-Cyano-Pyrimidines and-Triazines as Cysteine Protease Inhibitors
09/04/2008US20080214547 Using small molecules as binding ligands, for the recruitment of Fas-associated death domain protein, activation of death-inducing signaling complex, caspase-8, and apoptosis in malignant cells; anticarcinogens, antitumor agents; enhanced cellular differentiation, minimizing cytolysis to healthy cells
09/04/2008US20080214546 N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
09/04/2008US20080214545 4-{3-tert-butyl-5-[({[4-(pyridin-4-yloxy)phenyl]amino}carbonyl)amino]-1H-pyrazol-1-yl}-N-(2-pyrrolidin-1-ylethyl)benzamide; antiproliferatives; angiogenesis inhibitors
09/04/2008US20080214544 N-(4-(6-(1-methyl-6-oxo-2-(phenylamino)-1,6-dihydropyrimidin-5-yl)pyridin-3-yloxy)pyridin-2-yl)pyrrolidine-1-carboxamide; anticarcinogenics, antiproliferatives, angiogenesis inhibitors; hepatocyte growth factor mediated diseases
09/04/2008US20080214543 Antiandrogen; prostate cancer; excellent oral pharmacokinetics
09/04/2008US20080214542 1-(5-methoxyisoindolin-2-yl)-6-[4-(3-trifluoromethylphenyl)piperazin-1-yl]hexan-1-one; amidation of an isoindole with a 4-phenylpyrimidinylalkanoic acid or amination of a N-haloalkylcarbonyl isoindole with a 4-phenylpyrimidine; antidepressant, neuroleptic agent; drug abuse, impotency, Parkinson's Disease
09/04/2008US20080214541 Such as 2-(1-naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine; differentiating cells into osteoblast lineage; osteoporosis
09/04/2008US20080214540 3-[(phenyl or benzothiazol-2-yl)methyl]indole-N-acetic acids and esters; analgesics; aldose reductase inhibitors; diabetes complications including cataracts, retinopathy, nephropathy, and neuropathy; side effect reduction
09/04/2008US20080214539 Benzisoxazole Piperidine Compounds and Methods of Use Thereof
09/04/2008US20080214538 Pyridoindolone Derivatives Substituted in the 3-Position by a Phenyl, Their Preparation and Their Application in Therapeutics
09/04/2008US20080214537 Bridged phenanthridines
09/04/2008US20080214536 4-((4aR,10bR)-8,9-Dimethoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-6-yl)-N-(2-methoxyethyl)-N-methyl-benzamide; phosphodiesterase 4 inhibitors; respiratory system disorders
09/04/2008US20080214535 Rapidly solvent removed product of 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one (aprepitant) and carrier; solubility, bioavailability, drug delivery; neurokinin 1 receptor antagonist, antiemetics
09/04/2008US20080214534 (1,10B-Dihydro-2-(Aminoalkyl-Phenyl)-5H-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors
09/04/2008US20080214533 Anticoagulants, thrombolytic agents; amidating a p-(hydroxy-protected alkylamino)aniline with a (hetero)arylaminocarbonyl-(hetero)aryl carboxylic acid; deblocking, reacting with cyanogen bromide and cyclizing
09/04/2008US20080214531 Administering combination of niacin and meloxicam; reducing prostaglandin levels
09/04/2008US20080214530 Photo-Activated Disinfection
09/04/2008US20080214529 Such as n-{3-[1-(3,3-dimethyl-butyl)-4-hydroxy-2-oxo-1,2,4a,5,6,7-hexahydro-pyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxo-1,4-dihydro-1 lambda-6-benzo[1,2,4]thiadiazin-7-yl}-methane sulfonamide; hepatitis C viral infections; inhibiting replication
09/04/2008US20080214528 e.g. N-[3-{1-[(cyclobutyl)amino]-4-hydroxy-2-oxo-1,2-dihydro-quinolin -3-yl}-1,1-dioxo-1,4-dihydro-1 lambda 6-thieno[2,3-e][1,2,4]thiadiazin-7-yl)methyl]methane-sulfonamide; viricides for infections caused by an RNA-containing virus; hepatitis C virus (HCV) polymerase inhibitor; liver cirrhosis
09/04/2008US20080214527 Hiv Integrase Inhibitors
09/04/2008US20080214526 Macrocyclic Compounds and Compositions Useful as Bace Inhibitors
09/04/2008US20080214525 Alkyl 4- [4- (5-Oxo-2,3,5, 11A-Tetrahydo-5H-Pyrrolo [2, 1-C] [1,4] Benzodiazepine-8-Yloxy) -Butyrylamino]-1H-Pyrrole-2-Carboxylate Derivatives and Related Compounds For the Treatment of a Proliferative Disease
09/04/2008US20080214524 e.g. N-[2-(3-fluorophenyl)ethyl]-N'-isoquinolin-5-ylurea; opioid receptor inhibitor; analgesic, antiinflammatory agent; inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity
09/04/2008US20080214523 Method for treating severe heart failure and medicament therefor
09/04/2008US20080214522 Macrocyclic indole compounds, e.g., (7R)-14-cyclohexyl-21,24-dimethyl-7,8-dihydro-6H-7,11-(epiminoethanoiminopropanothio iminomethano)indolo[1,2-e][1,5]benzoxazocin-15-one 17,17-dioxide; hepatitis C virus polymerase inhibitors
09/04/2008US20080214521 N-2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-Im]pyrrolo[3,4-j]][1,7]benzodiazonin-11-yl]-N-methylbenzamide; staurosporine derivative; FLT-3 kinase inhibitor, activator of permeabilization of mitochondrial outer membrane, as of BAK; anticarcinogenic
09/04/2008US20080214520 e.g. 7-Chloro-3-(2,2,2-trifluoroacetyl)-6-trifluoromethanesulfonyloxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine; antidepressant, anxiolytic agent; obesity, obsessive/compulsive disorder
09/04/2008US20080214519 Chromane Substituted Benzimidazole Derivatives as Acid Pump Antagonists
09/04/2008US20080214518 Potentiation; overcoming drug resistance of such as klebsiella pneumoniae; kits
09/04/2008US20080214517 Modulation of the Expression of Estrogen Receptors for the Prevention or Treatment of Heart Disease
09/04/2008US20080214516 Methods and compositions for inhibiting tumor growth
09/04/2008US20080214515 Farnesoid X receptors agonist; liver diseases, hepatitis; increase HDL cholesterol, lower triglycerides
09/04/2008US20080214514 Derivatives in which cholesterol or a cholesterol moiety is attached via ester, amide, or ether bonds to one of a variety of "linkers," e.g., chemical groups including alkyl chains and aromatic groups, which are then connected to fullerene moiety; steroid moiety confers solubility in biofluids; imaging
09/04/2008US20080214513 Method of treating middle ear infections
09/04/2008US20080214512 Pharmaceutical preparation containing a gestagen, and kit and method for treating endometriosis using the preparation
09/04/2008US20080214511 e.g. 5-Amino-4'-chloro-13-dihydrospiro[indene-2,5'-pyrrolo[2,3-d]pyrimidin]-6'(7'H)-one; Calcitonin Gene-Related Peptide Receptor antagonist; anlgesic agent; headache, migraine or cluster headache
09/04/2008US20080214510 Treating patient having meibomian gland disease, aqueous tear deficiency, delayed tear clearance or recurrent comeal epithelial erosion by topically administering an effective amount of tetracycline or derivative to eye
09/04/2008US20080214509 Methods for enhancing the efficacy of vascular disrupting agents
09/04/2008US20080214508 O-phosphonooxymethyl propofol disodium salt; anasthetic, analgesic, anxiolytic agent, antidepressant; bioavailable and pharmacologically active when given by intravenous, than subcutaneous or rectal administration
09/04/2008US20080214507 Mono-and-di-phosphates of 3-(3-fluoro-4-hydroxy-phenyl)-7-hydroxy-naphthalene-1-carbonitrile
09/04/2008US20080214506 Applying to patient a medicament for transdermal, oral, or ophthalmological administration comprising ethanol, vitamin B6 or analog thereof, and an ion channel affinity component; providing transport vehicle of meperidine, lecithin, or DMSO for transfer of vitamin B6 or analog through cell membrane
09/04/2008US20080214505 Risedronate compositions and their methods of use
09/04/2008US20080214504 Vitamin B6 Related Compounds and Methods for Recovery From Trauma
09/04/2008US20080214503 Diethyl[2-({[7-[(4-fluorophenyl)methyl]-4-hydroxy-3-({[2-(methyloxy)ethyl]amino}carbonyl)-2-oxo-1,5-naphthyridin-1(2H)-yl]acetyl}amino)ethyl]phosphonate; alone or with a second enzyme inhibitor
09/04/2008US20080214501 Bruton's tyrosine kinase (Btk) activity probe comprising a Btk inhibitor moiety, a reporter moiety, and a linker moiety that links the inhibitor moiety to the reporter moiety; probes are used to characterize and develop Btk-selective inhibitors intended for therapeutic use
09/04/2008US20080214500 Injectable cement composition for orthopaedic and dental use
09/04/2008US20080214499 Lowering lipids in a living body by use of a cyclic tetrasaccharide represented by formula of cyclo{>6)- alpha -D-glucopyranosyl-(1>3)- alpha -D-glucopyranosyl-(1>6)- alpha -D-glucopyranosyl-(1>3)- alpha -D-glucopyranosyl-(1>}, and/or glycosylated compound(s) thereof
09/04/2008US20080214498 Osmotic glucose polymer, electrolyte, and buffer solutions administered to patient after heat sterilization; not subjected to glucose-like degradation during storage and sterilization, and having a pH value in neutral range
09/04/2008US20080214497 Water dispersible policosanol cyclodextrin complex and method of its production
09/04/2008US20080214496 Iron(III) polymaltose complex and iron(III)maltodextrin complex; improvements in immune defence and/or brain performance in patients who had a normal hematological result in respect of iron status
09/04/2008US20080214495 Heterocyclic Sulfonamide Derivatives as Inhibitors of Factor Xa
09/04/2008US20080214494 Method of drug delivery by carbon nanotube-chitosan nanocomplexes
09/04/2008US20080214493 Use of Flavone Compounds as Potassium Channel Inhibitors
09/04/2008US20080214492 Treating inflammation, oxidative stress, glycation/dysinsulinemia, platelet function, homocysteine levels and acetylcholinesterase inhibition; Alzheimer's disease; Parkinson's disease; cardiovascular diseases arterosclerosis and risk factors thereof including elevated cholesterol and blood pressure
09/04/2008US20080214491 Methods of Inhibiting the Interaction Between S100 and the Receptor for Advanced Glycation End-Products
09/04/2008US20080214490 Administering purinergic receptor agonist P1, P4-di(uridine 5'-) tetraphosphate for secretion stimulation; vaginal dryness associated with menopause, chemotherapy, and various disease states as well as the treatment of vulvar pain
09/04/2008US20080214489 Aptamer-mediated intracellular delivery of oligonucleotides
09/04/2008US20080214488 TRIGGERED RNAi
09/04/2008US20080214487 Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
09/04/2008US20080214485 Targeting inhibitory nucleic acid molecules to specific regions of an RNA encoding a polypeptide of interest can lead to the induction of a T cell response in an individual against the polypeptide; target polypeptide may be a tumor antigen or viral antigen
09/04/2008US20080214484 Nucleic acids encoding sarcocystis neurona antigen and uses thereof
09/04/2008US20080214483 Antisense-oligonucleotides for the treatment of immuno-suppressive effects of transforming growth factor-beta (TGF-beta)
09/04/2008US20080214482 Retromer-based assays and methods for treating alzheimer's disease
09/04/2008US20080214481 Methods of Treatment of Endobronchial Infections
09/04/2008US20080214480 Method for Treating Sickle Cell Disease and Sickle Cell Disease Sequalae
09/04/2008US20080214479 Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
09/04/2008US20080214471 Method for inhibition of viral infection
09/04/2008US20080214458 Administering a modulator that interacts with a neurotransmitter receptor; synapse-specific proteins, Rab3A, NMDA-1, synapsin-1, tetanus toxin receptor, BDNF-receptor and a GABA receptor
09/04/2008US20080214455 5Z)-2-[(2,6-Dichlorophenyl)amino]-5-{[3-(4-morpholinyl)-6-quinoxalinyl]methylidene}-1,3-thiazol-4(5H)-one; inhibiting hYAK3 proteins; autoimmunity, HIV, cancer, drug-induced anemias, myelodysplastic syndrome, aplastic anemia myelosuppression, cytopenia
09/04/2008US20080214453 Administering soluble receptor for advanced glycation endproduct (sRAGE)
09/04/2008US20080214452 Method for effecting localized, non-systemic and systemic, immunogenic treatment of cancer using crt translocation
09/04/2008US20080214449 Administering N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
09/04/2008US20080214445 Contains N-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine
09/04/2008US20080214443 Compositions and Methods for Control of Insect Infestations in Plants
09/04/2008US20080214437 RNA interference; gene therapy; inhalers
09/04/2008US20080214436 Methods and compositions for the treatment of cancer or other diseases
09/04/2008US20080214394 N-(4-Pyridyl)Methylsulfonamides For Combating Arthropodal Pests
09/04/2008US20080213889 Increasing oocyte maturation via treating oocyte in vitro with gonadotropin hormone and hydrolase inhibitor; treating fertility disorders
09/04/2008US20080213888 Neural precursor cells, method for the production and use thereof in neural defect therapy
09/04/2008US20080213863 Method of Controlling Viral Outbreak
09/04/2008US20080213861 Using targeted gene expression inhibition to treat and prevent viral infection
09/04/2008US20080213822 Methods for diagnosing celiac sprue and reagents useful therein
09/04/2008US20080213793 Antibodies that bind receptor protein designated 2f1
09/04/2008US20080213786 Using lectin modulators as treatments for cell proliferative and inflammatory disorders
09/04/2008US20080213427 Administering glutenase to Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides
09/04/2008US20080213409 Triple anti-irritant composition