| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
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| 10/09/2008 | US20080249181 Compositions Having Antimycrobial Activity Including a Hydroxamate or a Hydroxamate and a Hydroxlyamine |
| 10/09/2008 | US20080249180 N-(4-chloro-3-methoxy-phenyl)-N',N'-dimethyl-2-phenyl-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-malonamide; sleep disorders, insomnia, eating disorders, neurodegenerative disorders, sexual dysfuntion, pain, epilepsy; improved pharmacokinetics |
| 10/09/2008 | US20080249179 histone deacetylase (HDAC) inhibitor useful in selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells; have a high bioavailability and gives high blood levels of the active compounds over a long time |
| 10/09/2008 | US20080249178 Administering magnesium thronate to achieve a phsiological concentration of magnesium of >0.75 as determined under fasting conditions; enhancing synaptic plasticity; health, nutrients, cognition activators; Alzheimer's disease;, attention deficit hyperactivity disorder; and other nervous system disorders |
| 10/09/2008 | US20080249177 Selective beta 3-adrenoceptor stimulants; obesity, diabetes mellitus, hyperlipidemia, pollakiuria, urinary incontinence, intestinal hypermotility; e.g. 4'-{2-[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl ethylamino]ethoxy}-2,3',5'-trimethylbiphenyl-4-carboxylic acid |
| 10/09/2008 | US20080249176 Methods and Compositions for the Treatment of Myocardial Conditions |
| 10/09/2008 | US20080249175 N-Phenyloxamide derivatives |
| 10/09/2008 | US20080249174 A transgenic knockout animal whose genome comprises a heterozygous disruption of at least one endogenous gene, Sptlc1 and/or Sptlc2, encoding a serine palmitoyl-CoA transferase (SPT) subunit;screening SPT enzyme inhibitors for a ligand/protein binding Sptlc1 and/or Sptlc2; myriocin, antiatherosclerois |
| 10/09/2008 | US20080249173 Treatment of Apoptosis |
| 10/09/2008 | US20080249172 Cosmetic Oil Substances |
| 10/09/2008 | US20080249171 Administering diacylglycerols to accumulate fatty acids in the small intestine to suppress biosynthesis of triacylglycerols; antidiabetic agents; insulin resistance; lower blood remnant/leptin level, enhancement of beta -oxidation and uncoupling protein (UCP) expression to promote energy consumption |
| 10/09/2008 | US20080249170 Magnesium compositions and uses thereof for neurological disorders |
| 10/09/2008 | US20080249169 Ameliorating the effects of a metabolic disorder by administering a magnesium-containing compound effective to increase a physiological concentration of magnesium by at least about 10%; magnesium threoate; neutraceuticals; bioavailabilty; antidiabetic agents; accurate analysis; nervous system disorders |
| 10/09/2008 | US20080249168 Pharmaceutical composition for gout |
| 10/09/2008 | US20080249167 Compounds and methods for delivery of prostacyclin analogs |
| 10/09/2008 | US20080249166 Inhibiting hepatic fatty acid and sterol synthesis; use with statins; compounds such as cyclopropyl or cyclobutyl-functional hydroxy-functional alpha,gamma-alkanediacids |
| 10/09/2008 | US20080249165 Glycosides and Salts Thereof |
| 10/09/2008 | US20080249164 Antimicrobial and Antinflammatory Composition |
| 10/09/2008 | US20080249163 Process For Producing Product Containing Proanthocyanidin in High Proportion |
| 10/09/2008 | US20080249162 ATPase inhibitors; anticancer agents; synthesis and chemical intermediates thereto |
| 10/09/2008 | US20080249161 Diffusion solvent vehicle, including essential oils and poly-unsaturated fatty acids, uses capacity of sebaceous glands to store active ingredients and to release the ingredients through a sebum; salting out |
| 10/09/2008 | US20080249159 Ingesting daily a compound of tetrahydrolipstatin (Orlistat) for a period of at least two years to prevent weight regain; long-term therapy so as to permanently atrophy the endocrine cells which would otherwise generate more ghrelin; appetite reduction |
| 10/09/2008 | US20080249158 Pyrrole derivatives as therapeutic compounds |
| 10/09/2008 | US20080249157 Novel Inhibitors of the Lfa-1/Icam-1 Interaction and Uses Thereof |
| 10/09/2008 | US20080249156 Combinations of statins and anti-obesity agent and glitazones |
| 10/09/2008 | US20080249155 5-Hydroxyindole-3-Carboxylate Derivatives and Uses Thereof |
| 10/09/2008 | US20080249154 Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates |
| 10/09/2008 | US20080249153 Anthelmintic formulations |
| 10/09/2008 | US20080249152 Complexes with radionuclides; radiotherapy or diagnosis of tumors; e.g. two tetraazacyclododecanetetraacetic acid (DOTA) chelators conjugated to the side of biotin |
| 10/09/2008 | US20080249151 Non-nucleoside reverse transcriptase inhibitors |
| 10/09/2008 | US20080249150 Heterocyclic sulfonamide inhibitors of beta amyloid production containing an azole |
| 10/09/2008 | US20080249149 Serotonin receptor antagonists |
| 10/09/2008 | US20080249148 For contraception, treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, and hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake, and synchronizing estrus |
| 10/09/2008 | US20080249147 Emulsion-Stabilized Preparation |
| 10/09/2008 | US20080249146 Bicyclic antivirals for hepatitis C treatment; e.g. 1-cyclohexyl-2-phenyl-1H-thieno[3,2-d]imidazole-5-carboxylic acid |
| 10/09/2008 | US20080249145 Of N-[2-(Diethylamino)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-3-[2-(1-naphthyl)ethoxy]propanamide; asthma and chronic obstructive pulmonary disease |
| 10/09/2008 | US20080249144 Preventive or Therapeutic Agent for Chronic Inflammatory Lung Disease |
| 10/09/2008 | US20080249143 New formulations and use thereof |
| 10/09/2008 | US20080249142 N-methyl-5-(5-isopropoxy-3-pyridinyl)-4-penten-2-amine p-hydroxybenzoate; compounds can activate nicotinic receptor and can modulate neurotransmitter secretion; neuroprotective agents; side effects reduction; pains; easy to remove impurities; heck coupling reaction; CNS disorders; inflammatory disorders |
| 10/09/2008 | US20080249141 Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters |
| 10/09/2008 | US20080249140 Quaternary 3 -Amido, N-Methylpyridinium Salts as Anti-Inflammatory Agents |
| 10/09/2008 | US20080249139 N-((1S,2R)-1-(3,5-difluorobenzyl)-3-{[(1S)-7-ethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-2-hydroxypropyl)pyrazine-2-carboxamide for example; or corresponding sulfonamides; beta-secretase inhibitors; dementia; Alzheimer's disease |
| 10/09/2008 | US20080249138 Pyridine Compounds For The Treatment Of Prostaglandin Mediated Diseases |
| 10/09/2008 | US20080249137 e.g. {3-butoxy-5-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-phenyl}-acetic acid; peroxisome proliferator activated receptor modulator; antidiabetic agent; obesity, hyperlipidemia, dyslipidemia, hypertriglyceridemia, Syndrome X, insulin resistance, diabetic neuropathy, atherosclerosis, eczema |
| 10/09/2008 | US20080249135 Compounds for alzheimer's disease |
| 10/09/2008 | US20080249134 New Esomeprazole Sodium Salt Crystal Modification |
| 10/09/2008 | US20080249133 Use of Substituted 2-Thio-3,5-Dicyano-4-Phenyl-6-Aminopyridines In the Treatment of Nausea and Vomiting |
| 10/09/2008 | US20080249132 Piperidine Carboxyamide Derivate Suitable as Tachykinin Receptor Antagonist |
| 10/09/2008 | US20080249131 treatment of HIV; N-(2-Bromo-4-methylphenyl)-2-(5-methyl-4-phenyl-4H-[1,2,4]triazole-3-ylsulfanyl)-acetamide |
| 10/09/2008 | US20080249130 Oral dosage forms; antiproliferatives, anticholesterol agents; lipid metabolic disorders; myocardial infarction, stroke, restenosis, atherosclerosis |
| 10/09/2008 | US20080249129 Compositions and Methods for Treatment of Protein Misfolding Diseases |
| 10/09/2008 | US20080249128 N-{2-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-2-oxo-ethoxy]-ethyl}-N-ethyl-4-methoxy-2,3,6-trimethyl-phenylsulfonamide; condensing the N-carboxyalkyl phenylsulfonamide with the substituted piperidine; bradykinin receptor antagonists; analgesics; antidiabetics; angiogenesis inhibitors; rheumatic diseases |
| 10/09/2008 | US20080249127 Muscarinic Acetylcholine Receptor Antagonists |
| 10/09/2008 | US20080249126 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups, processes for their preparation and their use as pharmaceuticals |
| 10/09/2008 | US20080249125 N-methyl-2-phenyl-2-{7-[2-(4-trifluoromethyl-phenyl)-ethyl]-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl}-acetamide; sleep disorders |
| 10/09/2008 | US20080249124 Conjugate linkage is removable upon administration; 41-Desmethoxyrapamycin-L-wortmannin; antineoplastic agents |
| 10/09/2008 | US20080249123 Wortmannin-rapamycin conjugate and uses thereof |
| 10/09/2008 | US20080249122 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-1 receptor |
| 10/09/2008 | US20080249121 Condensing (3-trifluoromethylsulfonyl) benzoyl chloride and 4-methyl-2-nitro-aniline; reducing nitro group with stannous chloride; condensing amino group with cyanamide; cyclocondensing guanidine group with 3-dimethylamino-1-pyridin-3-yl-propenone; antiproliferative agent |
| 10/09/2008 | US20080249120 Pharmaceutical compositions |
| 10/09/2008 | US20080249119 Nucleosiding a protected cytosine with a protected hexose, deprotecting to obtain gemcitabine; administering as produgs; cancers of the lungs, ovaries, pancreas and bladder; cost efficiency; simplification |
| 10/09/2008 | US20080249118 diagnosing prostate carcinoma by determining the methylation degree in the genomic locus of a gene selected from the group consisting of 14-3-3 sigma , DDB2, GPX3, GSTM1, SFRP1, DKK3, p57/KIP2, COX-21PTGS2, HPGD and combinations thereof in a sample, wherein a hypermethylation is indicative of cancer |
| 10/09/2008 | US20080249117 Alopecia therapy using tetrazole compound |
| 10/09/2008 | US20080249116 Aldehyde dehydrogenase; 3-(4-hydroxyphenyl)-7-[(5-phenyl(1,2,4-oxadiazol-3-yl))methoxy]-3-hydroquinazolin-4-one; alcoholism; cocaine and nicotine addictions |
| 10/09/2008 | US20080249115 small molecule, non-peptide, modulators (e.g., antagonists or agonists) of peptide hormones; treating low blood pressure or an eating disorder |
| 10/09/2008 | US20080249114 Beta-3 adrenergic receptor agonists; urinary tract infections, incontinence, gastrointestinal disorders, dysmenorrhea, obesity; tocolytic, anxiolytic, antidiabetic agents; antidepressants; 4-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propoxy)phenol |
| 10/09/2008 | US20080249112 Antiproliferavtive agents; small molecule inhibitors of KSP(kinesin-related proteins); N-(3-aminopropyl)-N-[1-(3-benzyl-4-oxo-6,7,8 ,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-2-yl)propyl]-4-bromobenzamide |
| 10/09/2008 | US20080249111 Piperdine Derivatives as CCR5 Inhibitors |
| 10/09/2008 | US20080249110 Novel Substituted 3-Sulfur Indoles |
| 10/09/2008 | US20080249109 Pyrazinoylguanidine compounds for use as taste modulators |
| 10/09/2008 | US20080249108 treatment of sleep disorders or inflammatory diseases of the bladder by administering N-benzyl-2-phenylpiperazine-1-carboxamides, e.g., 2-(S)-(4-Fluoro-2-methyl-phenyl)-piperazine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methyl-amide methansulfonate |
| 10/09/2008 | US20080249107 Comprising trihydroxy phenyl subunits; selectin inhibitors; side effect reduction; 3-{3-[3-(3,4,5-Trihydroxy-phenyl)-propionylamino]-phenylamino}-benzoic acid |
| 10/09/2008 | US20080249106 3-(1-((R)-7-((4-fluoropiperidin-1-yl)methyl)-3,4-dihydro-2H-chromen-4-yl)-1H-1,2,3-triazol-4-yl)-2-(4-methylphenylsulfonamido)propanoic acid; chronic pain analgesics; side effect reduction |
| 10/09/2008 | US20080249105 And Erectile Dysfunction; rho kinase inhibitors; [3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]amine |
| 10/09/2008 | US20080249104 Salt Forms of 4- (4-Methylpiperazin-1-Ylmethyl) -N- [4-Methyl-3- (4-Pyridin-3-Yl) Pyrimidin-2-Ylamino) Phenyl]- Benzamide |
| 10/09/2008 | US20080249103 determining presence or absence of polymorphic variant in biological sample from subject in nucleic acid sequence that encodes sirtuin protein or controls expression of a sirtuin gene; presence of variant is indicative that subject would be responsive to treatment with a sirtuin modulating compound |
| 10/09/2008 | US20080249102 Hiv Protease Inhibitors |
| 10/09/2008 | US20080249101 BENZOIMIDAZOLE, TETRAHYDRO-QUINOXALINE, BENZOTRIAZOLE, DIHYDRO-IMIDAZO[4,5-c] PYRIDINONE AND DIHYDRO-ISOINDOLONE DERIVATIVES |
| 10/09/2008 | US20080249100 N-[2-(2-{[(3,4-dichlorophenyl)methyl]amino}-7-oxo-8-hydropteridin-8-yl)ethyl]carboxamides; antidiabetic, anticholesterol, anticarcinogenic, antiischemic, hypotensive agents; obesity, stroke |
| 10/09/2008 | US20080249099 7-Phenylalkyl Substituted 2-Quinolinones and 2-Quinoxalinones as Poly(Adp-Ribose) Polymerase Inhibitors |
| 10/09/2008 | US20080249098 peripheral benzodiazepine receptors; 7-fluoro-N,N,5-trimethyl-4-oxo-3-(pyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-carboxamide; for the treatment of various types of peripheral neuropathies, amyotrophic lateral sclerosis |
| 10/09/2008 | US20080249097 antiviral, anticancer chemotherapeutic agents; hydrophobic prodrugs of bases, nucleosides, and nucleotides; improved pharmacokinetic properties |
| 10/09/2008 | US20080249096 Pharmaceutical Forms with Improved Pharmacokinetic Properties |
| 10/09/2008 | US20080249095 tyrosine kinase inhibitors, in particular Met kinase; antitumor agents;1-(Benzo-1,2,5-thiadiazol-5-ylmethylcarbonyl)-3-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazole; leukemia, carcinomas |
| 10/09/2008 | US20080249094 Compounds for the treatment of neurodegenerative disorders |
| 10/09/2008 | US20080249093 immunosuppressive, anti-inflammatory and hemostatic agents to modulate leukocyte trafficking, sequestering lymphocytes in secondary lymphoid tissues, and enhancing vascular integrity; safer and more effective; 3-(4-(5-(3-Cyano-4-isopropyloxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid |
| 10/09/2008 | US20080249092 3-(phenylsulfonyl)-N-(tetrahydro-2H-pyran-4-ylmethyl)-8-quinolinamine; selectively modulating the cannabinoid 2 receptor; treatment of CNS disorders |
| 10/09/2008 | US20080249091 Indoles Useful in the Treatment of Inflammation |
| 10/09/2008 | US20080249090 1-(4-(1H-pyrrol-1-yl)phenyl)-3-(2-aminoquinazolin-6-yl)-4-methylpyridin-2(1H)-one; modulators of kinase enzymes such as c-kit, and useful for the regulation of autoimmune disease(s), allergies, asthma, cancer and the like |
| 10/09/2008 | US20080249089 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| 10/09/2008 | US20080249088 consisting of benzylamine derivatives and morpholine derivatives; an aliphatic alcohol substituted with an aromatic substituent in which the antifungal compound is soluble to a therapeutically effective concentration; can be applied topically in solution; and a distribution solvent |
| 10/09/2008 | US20080249087 Heterocylic antiviral compounds |
| 10/09/2008 | US20080249086 N-benzyl-N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}methane-sulfonamide; trial and ventricular arrhythmias; pharmacokinetics; electrophysiological activity; lowering daily clinical dose, lengthening duration of action; side effect reduction; arrhythmia |
| 10/09/2008 | US20080249085 for treating cell proliferative diseases; maytansinoid analogs; with lower systemic toxicity, improved pharmacokinetic profile, and better clinical activity; inhibiting fungal growth; compounds can target tubulin, Heat Shock Protein-90 |
| 10/09/2008 | US20080249084 For diabetes, obesity or metabolic syndrome; improve physicochemical (like stability) and biological (inhibitor activity, specificity, bioavailability, metabolism) profiles; 11Beta-hydroxysteroid dehydrogenase 1 inhibitors; 3-chloro-4-[4-methyl-5-(1-phenyl-cyclopropyl)-4H-[1,2,4]triazol-3-yl]-benzamide |
| 10/09/2008 | US20080249083 isolated nucleic acids coding for novel glutaminyl-peptide cyclotransferase-like proteins (QPCTLs); isoenzymes; useful for the discovery of new therapeutic agents, for measuring cyclase activity; Alzheimer's disease, Familial British Dementia, Familial Danish Dementia, Down Syndrome, Huntington's disease |
| 10/09/2008 | US20080249082 Use of Memantine (Namenda) to Treat Autism, Compulsivity and Impulsivity |
| 10/09/2008 | US20080249081 Compounds for the treatment of pain and screening methods therefor |
| 10/09/2008 | US20080249080 Benzodiazepine Derivatives and Uses Thereof on Medical Field |
| 10/09/2008 | US20080249079 Pyrimidine Derivatives As Kinase Modulators and Method of Use |