| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
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| 02/02/2010 | US7655795 (3R,4R)-1-[(9-deazahypoxanthin-9-yl)methyl]-3-hydroxy-4-hydroxymethyl-pyrrolidine; reaction of formaldehydewith a cyclic amine and a heteroaromatic compound to give methylene linked cyclic amine deazapurines; cancer, bacterial, protozoal infections or T-cell mediated diseases |
| 02/02/2010 | US7655789 Short interfering RNA sequences for use as therapeutic tools in treatment of cancer, diabetes and nervous system disorders |
| 02/02/2010 | US7655788 Short interfering RNA sequences for use in treatment and prevention of cell proliferative, diabetic and nervous system disorders |
| 02/02/2010 | US7655785 Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof |
| 02/02/2010 | US7655780 Integrin-linked kinase and its uses |
| 02/02/2010 | US7655771 Polymorphisms in the human cyp3a4 and cyp3a7 genes and their use in diagnostic and therapeutic applications |
| 02/02/2010 | US7655768 Galactose derivative, drug carrier and medicinal composition |
| 02/02/2010 | US7655760 Antibodies to the polypeptide hormone phosphatonin |
| 02/02/2010 | US7655755 Breast cancer resistance protein (BCRP) and the DNA which encodes it |
| 02/02/2010 | US7655753 Conjugate |
| 02/02/2010 | US7655747 hydrolytically unsatable linkages including estes, acetals, imines, peptides, protiens, oligonucleotides near the reactive end of polymer provide for a sufficient ciculation period for drug-polymer conjugate, hydrolytically breakdown the conjugate to release bound drug; slowing rate of kidney clearance |
| 02/02/2010 | US7655717 Ointment composition for treating decubitus ulcers and methods for its making and its use |
| 02/02/2010 | US7655699 Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
| 02/02/2010 | US7655698 also contains taurine, sodium hyaluronate, vitamin E, manganese, zinc, sodium, and potassium |
| 02/02/2010 | US7655697 Oral pharmaceutical composition for targeted transport of a platinum complex into the colorectal region, method for producing and use as medicament thereof |
| 02/02/2010 | US7655696 Highly efficacious and highly safe composition of a Stilbene derivative and a platinum coordination compound cis-diaminedichloroplatinum (II) |
| 02/02/2010 | US7655695 N-hydroxy-N-(methylacylfulvene)urea; solid tumor in a lung, ovarian, prostate, breast, endometrial, bladder, renal, pancreatic, central nervous system, melanoma, colon carcinoma or hematologic cancer; leukemia |
| 02/02/2010 | US7655694 Phytoestrogenic isoflavone compositions, their preparation and use thereof for protection against and treatment of radiation injury |
| 02/02/2010 | US7655693 Compounds |
| 02/02/2010 | US7655692 Dissolving atorvastatin in alcoholic solvent comprising methanol, ethanol, 1-propanol, or isopropanol; high speed evaporation by spray drying |
| 02/02/2010 | US7655691 Indole compounds useful as serotonin selective agents |
| 02/02/2010 | US7655690 1-sulfonylindole derivatives, their preparation and their use as 5-HT6 ligands |
| 02/02/2010 | US7655688 Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
| 02/02/2010 | US7655687 Anti-inflammatory analgesic for external use |
| 02/02/2010 | US7655686 2-(6-oxo-1,7-diaza-spiro[4.4]non-7-yl)-propionamides such as 4-(S)-hydroxy-5-(S)-[2-(S)-(1-isobutyl-6-oxo-1,7-diaza-spiro(S)-[4.4]non-7-yl)-propionylamino]-2-(R)-methyl-6-phenyl-hexanoic acid butylamide; inhibitors of aspartic proteases such as beta-secretase |
| 02/02/2010 | US7655685 Cardiometabolic disorders like obesity, diabetes, hypertension and dyslipidemias, 3, 4-diarylpyrazole derivatives; highly selective; limited or no CNS adverse side effects, including mood disorders |
| 02/02/2010 | US7655684 1-(Urea-, thiourea- and cyanoguanidine-methylene)benzyl)imidaoles, treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson's disease and Huntington's disease |
| 02/02/2010 | US7655683 Imidazolopyrazole derivatives useful as selective androgen receptor modulators |
| 02/02/2010 | US7655682 Triple anti-irritant composition |
| 02/02/2010 | US7655681 Administering zonisamide; clearing mucus; protective patches |
| 02/02/2010 | US7655680 (E)-3-[2-(3,4-diethoxyphenyl)thiazole-4-yl]-1-(2-methoxyphenyl)propenone; inhibiting the activity of phosphodiesterase 4, the production of tumor necrosis factor alpha, and the production of interleukin 4; atopic dermatitis |
| 02/02/2010 | US7655679 Derivatives of 2-aminothiazoles and 2-amino-oxazoles, processes for their preparation and their use as pharmaceutical compositions |
| 02/02/2010 | US7655678 Calcium glucarate, nicotinamide, and butyric acid |
| 02/02/2010 | US7655676 Selective activity against propionibacterium acne; minimum inhibitory concentration (MIC) against Propionibacterium acnes strains both sensitive and resistant to erythromycin and clindamycin and against a series Staphylococcus strains |
| 02/02/2010 | US7655675 Gamma-secretase inhibitors |
| 02/02/2010 | US7655674 Hedgehog antagonists that inhibit the hedgehog pathway in a smoothened gain-of-function cell with an IC50 within a factor of 20, 10, or even a factor of 5, of the IC50 with which they inhibit the hedgehog pathway in a patched-null cell |
| 02/02/2010 | US7655673 39-desmethoxyrapamycin, compositions and methods of use thereof |
| 02/02/2010 | US7655671 Morphinan derivatives, the quaternary ammonium salts thereof substituted in position 14, method for production and use thereof |
| 02/02/2010 | US7655670 1-((tetrahydropyran-2-yl)oxy-ethyl)-5-tert-butoxycarbonyl-spiro[indoline-3,4'-piperidin]-2-one; ORL-1 (orphan opioid receptor) G-protein coupled receptor; brain, psychological disorders |
| 02/02/2010 | US7655669 Pyrimidineamide derivatives and the use thereof |
| 02/02/2010 | US7655668 sustained release topical gel containing 5-fluorouracil, salicylic acid, dimethylsulfoxide, water-swellable polymer, and adhesive |
| 02/02/2010 | US7655666 Substituted 1H-quinazoline-2,4-diones useful as AMPA receptor ligands |
| 02/02/2010 | US7655664 Hydantoin derivatives as metalloproteinase inhibitors |
| 02/02/2010 | US7655663 (2S)-4,4-difluoro-1-(2-{[1-(2-pyrazinyl)piperidin-4-yl]amino}acetyl)-2-pyrrolidine carbonitrile; enzyme inhibitors; diabetes |
| 02/02/2010 | US7655662 For rho kinase-mediated diseases; (S)-N1-[6-(3-Methyl-1H-indazole-5-yl)-pyrazin-2-yl]-3-phenyl-propane-1,2-diamine dihydrochloride; eye disorders |
| 02/02/2010 | US7655661 Prodrugs of CC-1065 analogs |
| 02/02/2010 | US7655660 Antitumor antibiotic; water solubility, stability; N-[2-{(1-chloromethyl)-1,2-dihydro-5-[(4-methylpiperazino)carbonyloxy]-3H-benz(e)indol-3-yl}carbonyl]-1H-indol-5-yl]-5-[(3-methyldithio-1-oxopropyl)-amino]-1H-indole-2-carboxamide |
| 02/02/2010 | US7655659 By inhibiting prostaglandin or cyclooxygenase-2 production; indolequinazoline alkaloids rutaecarpine or evodiamine, and butylated hydroxytoluene; skin disorders: erythromelalgia, Raynaud's Disease |
| 02/02/2010 | US7655658 Thieno [2,3-D]pyrimidine-2,4-dione melanocortin-specific compounds |
| 02/02/2010 | US7655657 5-{6-[(3R)-1-azabicyclo[2.2.2]oct-3-yloxy]pyridazin-3-yl}-1-H-indole tartaric acid salt; nicotinic acetylcholine receptor modulation |
| 02/02/2010 | US7655656 crystalline 6-[[(3S,4R)-3,4-dihydro-3-hydroxy-6-[(3-hydroxypheny)sulfonyl]-2,2,3-trimethyl-2H-1-benzopyran-4-yl]oxy]-2-methyl-3(2H)-pyridazinone; industrial scale |
| 02/02/2010 | US7655655 Improving upon the known ability of D-cyclosporin to enhance extinctionlearning by administering the drug after extinction training and withintwo hours prior to the patients nightly sleep period; psychotherapy; achronic basis; antidepressants; eating/sexual/sleep disorders;analgesics; autism |
| 02/02/2010 | US7655654 Tetrazole substituted quinazoline compounds for antiproliferation agents |
| 02/02/2010 | US7655653 Tetrahydrobenzfluorene derivatives |
| 02/02/2010 | US7655652 Imidazolo-5-yl-2-anilinopyrimidines as agents for the inhibition of cell proliferation |
| 02/02/2010 | US7655651 Biphenyl-4-carboxylic acid (4-chloro-3-{7-[4-(2-diethylamino-ethoxy)-phenylamino]-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl}-phenyl)-amide; protein kinase inhibitors |
| 02/02/2010 | US7655650 Oxadiazine derivatives |
| 02/02/2010 | US7655649 Inhibitors of Akt activity |
| 02/02/2010 | US7655648 Antibacterial agents |
| 02/02/2010 | US7655647 3-[(1-oxo-2-cyclopropylmethyl-heptyl)]amino-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; amyloid precursor protein and beta -peptide inhibitor; beta or gamma secretases inhibitor; amyloid plaques and neurofibrillar tangles; neurodegenerative diseases: Alzheimer's disease; Down syndrome |
| 02/02/2010 | US7655646 Antineoplastic agents |
| 02/02/2010 | US7655645 Indole derivatives |
| 02/02/2010 | US7655644 Piperidine and azetidine derivatives as GlyT1 inhibitors |
| 02/02/2010 | US7655643 (8S,11S,14S)-14-Amino-11-(3-aminopropyl)-5-fluoro -17-hydroxy-10,13-dioxo-9,12-diazatricyclo[14.3.1.12,6]henicosa-1(20),2(21),3,5,16,18-hexaene-8-carboxylic acid dihydrochloride; antibacterial activity on S. aureus strains which are resistant to biphenomycin |
| 02/02/2010 | US7655642 3-cyano-quinoline derivatives with antiproliferative activity |
| 02/02/2010 | US7655641 3-(4-{2-[(5-Fluoro-3- methyl-benzo[b]thiophene-2- sulfonyl)-propyl- amino]-ethylsulfanyl}- 2-methyl-phenyl)- propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, hypertension, arteriosclerosis and cardiovascular diseases |
| 02/02/2010 | US7655640 silyl camptothecin derivatives for cancer and/or leukemia; cytotoxic; DNA-topoisomerase I inhibitors; antitumor agents; 7-trimethylsilyl-10-acetoxy camptothecin, 7-trimethylsilyl-11-fluoro camptothecin |
| 02/02/2010 | US7655639 Injection using a small bore needle a polysaccharide gel composition of dextran particles and hyaluronic acid which is collagen/ elastin-free; fibers; injecting an ingrowth of fibroblasts to form and aggregate collegen/elatin fibers in-situ; filling the spatial void; percutaneous closure |
| 02/02/2010 | US7655638 Partial and full agonists of A1 adenosine receptors |
| 02/02/2010 | US7655637 N-pyrazole A2A receptor agonists |
| 02/02/2010 | US7655636 Use of A2A adenosine receptor agonists |
| 02/02/2010 | US7655635 Suppression of nuclear factor-κB dependent processes using oligonucleotides |
| 02/02/2010 | US7655634 Use of hepatitis B X-interacting protein (HBXIP) in modulation of apoptosis |
| 02/02/2010 | US7655633 Beta-D-Glucopyranosyloxy)-3-(3-fluoro-4-methylbenzyl)-4,6-dimethylpyridine; sodium glucose co-transporter 2 (SGLT2) inhibitors; excellent hypoglycemic effect by excreting excess glucose into the urine through preventing the reabsorption of glucose at the kidney; antidiabetic agents; hyperglycemia |
| 02/02/2010 | US7655632 prevention or treatment of disease associated with hyperglycemia: diabetes, impaired glucose tolerance, impaired fasting glycemia, diabetic complications or obesity; e.g. 4-[(4-{3-[1-carbamoyl-1-(methyl)-ethylcarbamoyl]propyl}-2-methylphenyl)methyl]-3-( beta -D-glucopyranosyloxy)-5-isopropyl-1H-pyrazole |
| 02/02/2010 | US7655631 Pharmaceutical preparations and methods for inhibiting tumors |
| 02/02/2010 | US7655630 Abuse-resistant amphetamine prodrugs |
| 02/02/2010 | US7655621 Cross-linked glycopeptide-cephalosporin antibiotics |
| 02/02/2010 | US7655616 Traumatic brain and spinal cord injury treatment; administering interleukin-1B converting enzyme (capsase-1) inhibitor |
| 02/02/2010 | US7655468 Noncovalent complex having net positive charge at pH 6.0-8.0, the complex comprising a nucleic acid, at least one cationic lipid, and a polycation, where polycation is a cationic peptide or a polypeptide comprising polylysine, polyornithine, or polyarginine; gene therapy |
| 02/02/2010 | US7655467 vascular permeability agents (VPAs), such as VEGF, used in conjunction with adeno-associated virus(AVV) a nucleic acid viral vectors; nucleic cid sequences encoding Igf-1( insulin like growth factor-1) and dystrophin or dystrophin-like proteins; muscular disorders |
| 02/02/2010 | US7655462 Anti-tumor activity of Ea-4-peptide of pro-IGF-I |
| 02/02/2010 | US7655445 Synthesis of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides; rapid synthesis; high product yield |
| 02/02/2010 | US7655423 Central nervous system disorders; cognition activators |
| 02/02/2010 | US7655420 Identifying sclerostin antagonist via abilty to prevent apoptosis; treating osteoporosis |
| 02/02/2010 | US7655408 PCA3 messenger RNA species in benign and malignant prostate tissues |
| 02/02/2010 | US7655398 Compositions and methods for detection and treatment of proliferative abnormalities associated with overexpression of human transketolase like-1 gene |
| 02/02/2010 | US7655259 Delayed release carnitine |
| 02/02/2010 | US7655258 Biodegradable copolymer, and polymeric micelle composition containing the same |
| 02/02/2010 | US7655256 Pharmaceutical formulation including a resinate and an aversive agent |
| 02/02/2010 | US7655251 Amphiphilicmonocatenary glycosylated hydrocarbon nitrones; oxidation resistance;free radical scavengers; neuroprotectants; cosmetic products for the skin, hair andnails; imunotherapy; antiinflammatory agents; Alzheimer's disease; Parkinson'sdisease; aging resistance; radiation injuries |
| 02/02/2010 | US7655246 Chlamydia protein, gene sequence and uses thereof |
| 02/02/2010 | US7655231 Methods for treating pain by administering a nerve growth factor antagonist and an NSAID |
| 02/02/2010 | US7655224 Neural stem cells and use thereof for brain tumor therapy |
| 02/02/2010 | US7655221 Methods of treating disease with random copolymers |
| 02/02/2010 | US7654957 Apparatus for physical measurements of the eye |
| 02/02/2010 | CA2587149C Substituted n-sulfonylaminobenzyl-2-phenoxyacetamide compounds |
| 02/02/2010 | CA2578722C Process for atorvastatin calcium amorphous |
| 02/02/2010 | CA2530159C N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors |
| 02/02/2010 | CA2516682C Imidazol-4-yl-ethynyl-pyridine derivatives |