Patents
Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912)
05/2010
05/11/2010US7714023 Treatment or prophylaxis of migraine or headache disorders using citalopram, escitalopram or citalopram metabolites
05/11/2010US7714022 Decrease the secretion of the amyloid plaque forming peptide, A beta 42; neurodegenerative disease such as mild cognitive impairment, Alzheimer's disease and MCI (mild cognitive impairment); carboxy-substituted 1,2-diphenylpyrroles
05/11/2010US7714021 Pyrrolidin-3-yl compounds useful as beta-secretase inhibitors for the treatment of Alzheimer's disease
05/11/2010US7714020 Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate
05/11/2010US7714019 Indole, azaindole and related heterocyclic pyrrolidine derivatives
05/11/2010US7714018 Heterocyclic antiviral compounds
05/11/2010US7714017 Carboxylic acid peri-substituted bicyclics for occlusive artery disease
05/11/2010US7714016 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indole-4-one (CBI) with incorporated alkylating domain; in vivo drug-cleavable substrate conjugates that are potent cytotoxins; antiproliferative, anticarcinogenic agent; leukemia; bone marrow and mucosal toxicity; chronic cardiac and neurological toxicity
05/11/2010US7714015 Method and composition for treating sunburned skin
05/11/2010US7714014 N-(5-Hydroxypentyl)-1,3,5-triphenyl-4,5-dihydro-pyrazole-4-carboxyamide; inhibits tumorigenesis, tumor growth and tumor survival; inhibits Hedgehog and GLI signaling pathways
05/11/2010US7714013 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents
05/11/2010US7714012 Synthesis and biological activities of new tricyclic-bis-enones (TBEs)
05/11/2010US7714011 Compositions to reduce congestion and methods for application thereof to the nasal membrane
05/11/2010US7714010 N-[5-(2-Cyclopropoxy-ethyl)-7,7-dimethyl-6-oxo-3,5,6,7-tetrahydro-imidazo[4,5-f]indol-2-yl]-benzamide; tubulin-binding molecules
05/11/2010US7714009 Nitrogen-containing fused heterocyclic compounds
05/11/2010US7714008 Heterocyclic GPR40 modulators
05/11/2010US7714007 Administering glutaminase inhibitor to a subject suffering from chronic pain at a site of inflammation for therapy of chronic pain
05/11/2010US7714006 reducing the effect of a patient's age on the oral bioavailability by taking metaxalone with food; sedatives for treating muscular disorders
05/11/2010US7714005 Small molecule Bcl-xL/Bcl-2 binding inhibitors
05/11/2010US7714004 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
05/11/2010US7714003 Imidazo[2,1-b ]-1,3,4-thiadiazole sulfonamides
05/11/2010US7714002 Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
05/11/2010US7714001 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
05/11/2010US7714000 Substituted pyrrolidinones and their use as medicaments
05/11/2010US7713999 Thrombin receptor antagonists
05/11/2010US7713998 Nitrogenous heterocyclic compound and pharmaceutical use thereof
05/11/2010US7713996 2-Chloro-4-{[1-(3-chloro-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-benzoic acid; carnitine-dependent palmitoyltransferases (CPTs); liver beta -oxidation, consequently inhibit gluconeogenesis and therefore counteract hyperglycemia
05/11/2010US7713995 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
05/11/2010US7713994 Anticancer agents; cyclin dependent kinase inhibitors; (4Z)-6-[(3-aminophenyl)amino]-4-(([4-(piperidin-1-ylmethyl)phenyl]amino)methylene)isoquinoline-1,3(2H,4H)-dione for example
05/11/2010US7713993 1-(4-fluorophenyl)-3-{(E)-2-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]vinyl}-6,7-dihydro-5H-imidazo-[1,5-a]pyrazin-8-one; for diseases caused by amyloid- beta is Alzheimer's disease, dementia, Down's syndrome or amyloidosis
05/11/2010US7713992 adenosine receptor antagonists such as 2-(4-Methoxyphenyl)-9-benzylamino-10-cyano-s-triazolo[1,5-a]quinolin, used for treating respiratory system disorders, vision disorders, tumors, allergies or inflammatory disease, ischemia, hypoxia, arrhythmia or urogential disorders
05/11/2010US7713991 Imidazo[[1, 5-A] pyridine derivatives and methods for treating aldosterone mediated diseases
05/11/2010US7713990 3,8-substituted 8-AZA-bicyclo[3.2.1]octane derivatives and their use as monomine neurotransmitter re-uptake inhibitors
05/11/2010US7713989 Modulators and steroid receptors for treatment of diabetes, inflammatory diseases using prodrugs; arthritis, asthma, rhinitis and immunomodulation
05/11/2010US7713988 use for lowering blood glucose, treating diabetes, or increasing insulin release; 7-(4,5-Diphenylpyrimidin-2-yl)-6-heptynoic Acid
05/11/2010US7713987 N2-Chlorocarbonyl-N4-(2,2-dimethyl-3-oxo-4H-5-pyrido[1,4]oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine; kinase inhibitors; breast cancer; inhibiting signal transduction cascades in which Syk plays a role
05/11/2010US7713986 Compounds and methods for treatment of chemotherapy-induced anemia
05/11/2010US7713985 2-Phenyl-s-triazolo[4,3-c]quinazolin-3-one derivatives; neurodegenerative and central nervous system disorders; Parkinson's and Alzheimer's disease; restless leg syndrome; sleep, attention deficit, and psychological disorders; antidepressants; strokes, psychosis
05/11/2010US7713984 Pharmaceutical uses
05/11/2010US7713983 Voltage gated sodium and calcium channel inhibitors
05/11/2010US7713982 8-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione: hyperlipoproteinaemia, dyslipidaemia, heart failure, hypercholesteraemia, atherosclerosis, arteriosclerosis, and hypertriglyceridaemia
05/11/2010US7713981 Method and compounds for inhibition of cell death
05/11/2010US7713980 Antitumor agents; anticancer agents
05/11/2010US7713979 Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
05/11/2010US7713978 N-[6-[cis-3,5-dimethyl-1-piperazinyl]-3-(methyloxy)-2-pyridinyl]-3-fluoro-4-(5-methyl-2-furanyl)benzenesulfonamide; for treating gastrointestinal disorders; agonistic activity at the growth hormone secretagogue (GHS) receptors
05/11/2010US7713977 Drug for psychological and central nervous system disorders
05/11/2010US7713976 Drug for psychological and central nervous system disorders
05/11/2010US7713975 Syk-mediated disease such as allergic conjunctivitis; vernal conjunctivitis; vernal keratoconjunctivitis; and giant papillary conjunctivitis
05/11/2010US7713974 3-chloro-5-[6-chloro-2-fluoro-3-(1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl)-phenoxy]-benzonitrile; inhibit HIV reverse transcriptase and are useful for treating Human Immunodeficiency Virus (HIV) mediated diseases
05/11/2010US7713973 Kinase inhibitors
05/11/2010US7713972 Imidazotriazinone derivatives as PDE 7 (phosphodiesterase 7) inhibitors
05/11/2010US7713971 Antidiabetic agents; dyslipidemia; hhypoglycemic agents; atherosclerosis ; obesity; antiinflammatory agents; metabolism disorders
05/11/2010US7713970 Substituted cyclic urea derivatives
05/11/2010US7713969 Compositions and methods for treatment of cancer
05/11/2010US7713968 Substituted arylcyclopentenes as therapeutic agents
05/11/2010US7713967 Therapeutic substituted hydantoins, and related compounds
05/11/2010US7713966 Heterobicyclic metalloprotease inhibitors
05/11/2010US7713965 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
05/11/2010US7713964 Methods for treating asthmatic conditions
05/11/2010US7713963 Acylated indanyl amines and their use as pharmaceuticals
05/11/2010US7713962 Introducing into the subject a ligand capable of labelling aggregated paired helical filament (PHF) tau protein, determining the presence and/or amount of ligand bound to extracellular aggregated PHF tau in the medial temporal lobe of the brain, correlating the result of the determination
05/11/2010US7713961 Substituted 1,2-ethylenediamines, methods for preparing them and uses thereof
05/11/2010US7713960 Inhibition of the Raf/Mek/P-Erk pathway for treating cancer
05/11/2010US7713959 Affecting weight loss, increasing energy expenditure, increasing satiety; zonisamide
05/11/2010US7713958 Compounds and compositions as protein kinase inhibitors
05/11/2010US7713957 Pharmaceutical composition containing gabapentin or pregabalin and N-type calcium channel antagonist
05/11/2010US7713956 Dealkylated derivatives of pyrrolo[2,1-b]benzothiazepines with atypical antipsychotic activity
05/11/2010US7713955 Applying to a surface one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning
05/11/2010US7713954 Compositions and methods for treating cognitive disorders
05/11/2010US7713953 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs
05/11/2010US7713952 2-methylene-19,26,27-trinor-(20S)-1α-hydroxyvitamin D3 and its uses
05/11/2010US7713951 2-alkylidene-18,19-dinor-vitamin D compounds
05/11/2010US7713950 Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
05/11/2010US7713949 Compositions and methods for enhancing paracellular permeability across epithelial and endothelial barriers
05/11/2010US7713948 Use of 5-substituted nucleosides for reinforcing the apoptotic effect of cytostatic drugs
05/11/2010US7713947 Cladribine regimen for treating multiple sclerosis
05/11/2010US7713946 (4S,5S,2R,3R)-5-[(2-fluorophenylthio)methyl]-2-{6-[(2-hydroxycyclopentyl)amino]-purin-9-yl }oxolane-3,4-diol; used to treat , diabetes, decreased insulin sensitivity, Polycystic Ovarian Syndrome, Stein-Leventhal syndrome, and obesity
05/11/2010US7713945 Inhibition of dendritic cell function in organ grafts or allogeneic bone marrow transplants by blocking SH2-containing inositol phosphatase (SHIP) expression; preventing immune rejection; reducing antigen presenting cell function; administering interfering RNA specific for SHIP-1 mRNA
05/11/2010US7713944 Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells
05/11/2010US7713943 as a downstream target of the PI 3-kinase pathway, preferably as a downstream drug target
05/11/2010US7713942 Drug delivery able crossing cellular membranes; transdermal, electrostatic interaction and a hydrophobic interaction
05/11/2010US7713941 Tricyclic nucleosides or nucleotides as therapeutic agents
05/11/2010US7713940 Water-soluble isoflavone composition, process for producing the same, and use thereof
05/11/2010US7713939 1-Substituted-[1H-indene-6,1'-cyclopropane]-4-one derivatives: solid tumors and multi-drug resistant tumors; -cell leukemia, B-cell lymphoma, myeloma, T-cell leukemia, T-cell lymphoma, small leukemia, and small cell lymphoma
05/11/2010US7713936 Abuse-resistant amphetamine prodrugs
05/11/2010US7713933 Pharmaceutical composition containing an activin or inhibin stimulator
05/11/2010US7713931 Cross-linked glycopeptide-cephalosporin antibiotics
05/11/2010US7713929 fusion protein contains a rapid or intermediate acting insulin in combination with a long acting insulin; administered before breakfast, it covers the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours
05/11/2010US7713924 Methods for treating conditions associated with the accumulation of excess extracellular matrix
05/11/2010US7713569 Therapeutic and anti-oxidant for variety of health purposes, including treatment of skin damage; also useful as a natural antibacterial, antiviral and fungicidal agricultural product
05/11/2010US7713551 Dosage form containing a drug having average particle size of less than about 2000 nm prior to inclusion in the formulation, a surfactant and a gel forming agent selected from natural gelatin, a semi-syntheic gelatin, and a synthetic gelatin
05/11/2010US7713550 Controlled release sodium valproate formulation
05/11/2010US7713548 Amorphous solid dispersions
05/11/2010US7713546 unitary soft gel capsule for oral administration is prepared by heating rice bran oil under reduced pressure, adding a filler and then corosolic acid, cooling, encapsulating into a soft gel capsule; increased absorption of corosolic acid in human body
05/11/2010US7713543 Elastin stabilization of connective tissue
05/11/2010US7713538 Drug delivery from stents
05/11/2010US7713529 Methods for treating and preventing infectious disease
05/11/2010US7713528 Method for in vivo delivery of active compounds using reagent conjugate
05/11/2010US7713523 Solubilized CoQ-10 and carnitine
05/11/2010US7713522 using gutless adenovirus vector; gene therapy; gutless means incapable of expressing any adenovirus antigens; atherosclerosis