| Patents for A61K 31 - Medicinal preparations containing organic active ingredients (785,912) |
|---|
| 12/28/2010 | US7858657 treating lung cancer with PI-3 kinase inhibitor acetic acid 4-diallylaminomethylene-6-hydroxy-1- alpha -methoxymeth-yl-10 beta ,13 beta -dimethyl-3,7,17-trioxo-1,3,4,7,10,11 beta ,12,13,14 alpha ,15,16,17-dodecahydro-2-oxa-cyclopenta [ alpha ]phenanthren-11-yl ester |
| 12/28/2010 | US7858656 Controlled release formulations containing an active ingredient, preferably melatonin and the method of preparation |
| 12/28/2010 | US7858655 synergistic mixtures reduce damage to neurons after a neurodegenerative insult; time-release agents; antiischemic agents; amyotrophic lateral slerosis (ALS), Alzheimer's disease, Parkinson's disease, Hunntington's disease, multiple sclerosis |
| 12/28/2010 | US7858652 e.g.1-(1H-imidazol-4-ylmethyl)-2-methyl-2,3-dihydro-1H-indole; trace amine associated receptors (g-protein coupled receptor), especially TAAR1; antidepressant, anxiolytic agent; psychosis, Parkinson's disease; reductively amination and coupling of indole and 5-methylketone-imidazol |
| 12/28/2010 | US7858651 Angiotensin II receptor antagonists such as 2-butyl-4-chloro-1-[2'-(1H-tetrazol-5-yl)1,1'-biphenyl-methyl]imidazole-5-carboxylic acid, pivaloyloxymethyl ester, used as hypotensive agents |
| 12/28/2010 | US7858650 Medicinal composition for inhalation |
| 12/28/2010 | US7858649 Imidazole derivatives and their use for modulating the GABAA receptor complex |
| 12/28/2010 | US7858648 Nanotube complexes are water soluble, nontoxic; use in delivering biologicals such as DNA for gene therapy, DNA vaccines; amine salts derived from diethylenetriaminepentaacetic acid-modified nanotubes with anion such as DNA |
| 12/28/2010 | US7858647 Peroxisome proliferator-activated receptor agonists; insulin resistance; neurodegenerative disorders ; N-{2-[4-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-ethyl}-2-methoxy-4-trifluoromethyl-benzamide |
| 12/28/2010 | US7858646 1-(2-hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-phenyl)-ethanone; 6-(3-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio)isonicotinic acid; 1-(2-hydroxy-4-{3-[4-(2H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-3-trifluoromethyl-phenyl)-ethanone; treatment of migriane |
| 12/28/2010 | US7858645 Indazole derivatives |
| 12/28/2010 | US7858644 administering prostaglandin receptor antagonists such as N-[4-(4'-Methoxy-biphenyl-4-yloxymethyl)-5-methyl-furan-2-carbonyl]-benzenesulfonamide, used analgesics, neuroprtectants and diuretics, or for the treament of diabetes, tinitus, cancer, bone, blood, sleep, cardiovascular and sexual disorders |
| 12/28/2010 | US7858643 Crizotinib, a c-Met protein kinase inhibitor anticancer agent; 3-[(R)-1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine is crizotinib |
| 12/28/2010 | US7858642 Substituted hydroxyethylamine aspartyl protease inhibitors |
| 12/28/2010 | US7858641 melanocortin-4 receptor (MC4-R) agonists such as (3R,5S)-N-(2-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-1-oxo-1,2-dihydroisoquinolin-6-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used for the treatment of obesity or diabetes |
| 12/28/2010 | US7858640 Chemoattractant Receptor-homologous molecule expressed on T Helper cells type 2(CRTH2) antagonists, such as [8-chloro-3-(4-chlorobenzyl)-4-difluoromethoxy-2-ethylquinolin-5-yloxy]acetic acid, used as antiinflammatory agents or for the treatment of respiratory system, skin or gastrointestinal disorders |
| 12/28/2010 | US7858639 [1,2,4]triazolo[4,3-a]pyridazine derivatives such as 6-(2-chlorophenyl)-7-(4-chlorophenyl)-3-[[2-methyl-6-(trifluoromethyl)pyridin-3-yl]methyl]-[1,2,4]triazolo[4,3-a]pyridine, used for the treatment of obesity and hyperlipemia, or as antidiabetic, antilipemic, anticholesterol and hypotensive agents |
| 12/28/2010 | US7858638 Administering aminobutyric acid receptor modulators such as 2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-5-hydroxy-2-oxohexyl) -1-isoindolinone for prophylaxis of nervous system and developmental disorders; speech therapy |
| 12/28/2010 | US7858637 Administration of TLR7 ligands and prodrugs thereof for treatment of infection by hepatitis C virus |
| 12/28/2010 | US7858636 Use as coloring in coatings, printing inks and plastics, for producing aqueous polymer dispersions which absorb in the near infrared region, for producing markings which absorb infrared light and are invisible to the human eye, as infrared absorbers for heat management, active components in photovoltaics |
| 12/28/2010 | US7858635 such as ethyl 3-(1'-methyl-2'-oxospiro[cyclohexane-1,3'-indoline]-4-yl)-8-azabicyclo[3.2.1]octane-8-carboxylate, used for the treatment of nervous system disorders, psychological disorders, autoimmune diseases, gastrointestinal disorders, vision defects, obesity and cardiovascular disorders |
| 12/28/2010 | US7858634 dissolving 3-pyridyl-1-hydroxyethyliden-1,1-biphosphonic acid ( risedronic acid) in an aqueous solvent containing water or water and butanol/tert-/, adding a sodium base (NaOH, sodium methoxide, NaHCO3, Na2CO3, sodium acetate), freeze drying the mixture to form risedronate sodium in amorphous powder form |
| 12/28/2010 | US7858633 Cycloalkyl substituted pyrimidinediamine compounds and their uses |
| 12/28/2010 | US7858632 Purinergic receptor antagonists; genitourinary and pain-related diseases; for example, 5-(2-isopropyl-4,5-dimethoxybenzyl)-pyrimidine-2,4-diamine |
| 12/28/2010 | US7858631 such as (3R,5S)-N-(3-{2-[2-fluoro-4-(methyloxy)phenyl]ethyl}-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-7-yl)-3,5-dimethyl-N'-[(1S,2S,3S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]piperazine-1-carboximidamide, used as melanocortin-4 receptor (MC4-R) agonists, for the treatment of obesity or diabetes |
| 12/28/2010 | US7858630 serotonin 5-HT2a and dopamine D3 receptors modulators such as N-trans-{4-[2-(4-benzo[d]isoxazol-3-yl)-piperazin-1-yl)-ethyl]-cyclohexyl}-3-methoxy-propionamide, useful in the treatment of cognitive disorders, drug addiction, depression, anxiety, dementia and psychological disorders |
| 12/28/2010 | US7858629 3-{(3S)-4-{[1-(3-ethoxyphenyl)-2-(4-methylphenyl)-1H-imidazol-4-yl]carbonyl}-3 -[(isopropylamino)carbonyl]-1-piperazinyl}-1-naphthoic acid, useful for the treatment, control, or prevention of obesity and diabetes |
| 12/28/2010 | US7858628 inhibiting neuronal death, inducing proliferation and differentiation of a neuronal progenitor cell into a neuron and increasing the number of neurons, in humans |
| 12/28/2010 | US7858627 Topoisomerase-targeting agents |
| 12/28/2010 | US7858626 Pyrimidineamines as angiogenesis modulators |
| 12/28/2010 | US7858625 Conjugates and compositions for cellular delivery |
| 12/28/2010 | US7858624 such as methyl 2-((R)-((R)-1-((2S,3S)-5-(butylamino)-1-cyclohexyl-3-hydroxy-5-oxopentan-2-ylcarbamoyl)piperidin-3-yl)(3-chlorophenyl)methoxy)ethylcarbamate, used as hypotensive agents or for the treatment of cardiovascular disorders, vision defects, aldosteronism and obesity |
| 12/28/2010 | US7858623 Substituted amide derivatives and methods of use |
| 12/28/2010 | US7858622 calcitonin gene related peptide antagonists such as [(3-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-1-[4-[1-(3-ethoxy-3-oxopropyl)piperidin-4-yl]piperidin-1-yl]-1-oxopropan-2-yl]4-(3-oxo-5-phenyl-1H-1,2,4-triazol-2-yl)piperidine-1-carboxylate; headaches; diabetes; irritable bowel syndrome; hot flashes |
| 12/28/2010 | US7858621 Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same |
| 12/28/2010 | US7858620 Cyanoisoquinoline |
| 12/28/2010 | US7858619 Improved solubility, lower tendency to bind to plasma proteins and greater activity especially in serum-based assay systems; remodeling of heart after myocardial infarction; atherosclerosis; 2-[4-(4-Fluorophenoxy)benzenesulfonyl]-6-(2-piperidin-1-ylethoxy)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid |
| 12/28/2010 | US7858618 Compounds |
| 12/28/2010 | US7858617 2-hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one; inhibition of a lipase, esterase or phosphatase enzyme |
| 12/28/2010 | US7858616 treating excessive or abnormal endothelial cell proliferation comprising administering compounds such as 3-Z-[1-(4-dimethylaminomethylanilino)-1-(3-(2-carboxyethyl)phenyl)methylene]-6-chloro-2-indolinone; antitumor, anticarcinogenic or antiproliferative agents |
| 12/28/2010 | US7858615 (S)-(-)-1-(4-fluoroisoquinolin-5-Yl)Sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate |
| 12/28/2010 | US7858614 Therapeutic pyrazolonaphthyridine derivatives |
| 12/28/2010 | US7858613 Substituted benzo-condensed cycloheptanone derivatives and their use for producing drugs |
| 12/28/2010 | US7858612 administering 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzoazepine, a prodrug 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine for the treament of Crohn's disease |
| 12/28/2010 | US7858611 Treating nervous system disorders related to cellular degeneration, psychiatric conditions, cellular traumas and/or injuries; candesartan, captopril or telmisartan in combination with baclofen, or donepezil; ibudilast, theophylline, enoximone, rolipram, or vardenafil in combination with aliskerin |
| 12/28/2010 | US7858610 administering 4-{[2-(1R,2R,3R)-3-hydroxy-2-{(1E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-enyl}-5-oxocyclopentyl)ethyl]sulfanyl}butanoic acid or it's methyl ester to treat a patient with interstitial cystitis a urogenital disorder; pollakiuria, urgency of urination, pain in the reproductive organ |
| 12/28/2010 | US7858609 Solid ganaxolone formulations and methods for the making and use thereof |
| 12/28/2010 | US7858608 orphan nuclear receptor modulators such as 23-N-Carbacinnamyloxy-3 alpha ,7 alpha -dihydroxy-5 beta -norcholanylamine, used for the treatment of liver, gastrointestinal, kidney, cardiovascular or metabolic disorders |
| 12/28/2010 | US7858607 System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer |
| 12/28/2010 | US7858606 Triterpenoid derivatives |
| 12/28/2010 | US7858605 Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology |
| 12/28/2010 | US7858604 Method of treating human volume expansion mediated hypertension employing resibufogenin |
| 12/28/2010 | US7858603 neuroprotectants such as 1,4-cholestadien-3-one oxime, used for the treatment of neurodegenerative diseases |
| 12/28/2010 | US7858602 identifying a patient who is exhibiting signs of Alzheimer's disease;measuring and identifying carbonic anhydrase enzymes, than administering non-toxic amount of vitamin D3 to promotes the natural generation of the cell-specific carbonic anhydrase enzymes; aging resistance |
| 12/28/2010 | US7858601 tetracycline derivatives such as 4-Oximinominocycline, used for the treatment of bacterial infections, as antitumor agents, blocking tetracycline efflux and modulation of gene expression |
| 12/28/2010 | US7858600 Non-antibiotic resistant; Gram-positive and Gram-negative bacteria; Salmonella, Streptococcus, Escherichia |
| 12/28/2010 | US7858598 Reagents for detection of hypochlorous acid |
| 12/28/2010 | US7858597 formulations of ANGIOTENSIN II AT1 receptors antagonists, using the cyclodextrins or their derivatives, lipossomes and the biodegradable polymers; increasing the bio-availability of losartan |
| 12/28/2010 | US7858595 Food, dietetic product, drugs; oligosaccharide |
| 12/28/2010 | US7858594 telbivudine; increased solubility, improved bioavailability; hepatitis B |
| 12/28/2010 | US7858593 Inhibitors of prolyl-hydroxylase-1 for the treatment of skeletal muscle degeneration |
| 12/28/2010 | US7858591 Oligonucleotide sequences which bind biomolecules such as peptides; selectively bind coagulation factors, E2F family members, Ang1 or Ang2; hydrophobic molecules and extracellular proteins for diagnosing and treating cardiovascular disorders in mammals |
| 12/28/2010 | US7858589 A saponin possessing immune adjuvant activity, derived from Quillaja saponaria; an immunostimulatory oligonucleotide cotaining an unmethylated CpG dinucleotide,wherein the immunostimulatory oligonucleotide is not a part of a DNA vaccine vector |
| 12/28/2010 | US7858588 Oligodeoxynucleic acid modified with (thio)phosphate |
| 12/28/2010 | US7858587 very good inhibitory effect on the sodium-dependent glucose cotransporter; suitable for the treatment of metabolic disorders (diabetes, dyslipidemia, atherosclerosis, high blood pressure, chronic heart failure and edema, reactive hypoglycaemia) |
| 12/28/2010 | US7858584 Angiogenically effective unit dose of FGF and method of administering |
| 12/28/2010 | US7858346 Regeneration and neogenesis of retinal visual cell-expressing Otx2 protein |
| 12/28/2010 | US7858322 Method of determining inhibition of binding to TRPM7 protein |
| 12/28/2010 | US7858316 Testing a compound for its ability to interupt a tmRNA structural domain selected from a H2 helix, a H5 helix, a PK1 pseudoknot, a PK2 pseudoknot, a PK3 pseudoknot or a PK4 pseudoknot to identify a drug candidate for treating a bacterial infection |
| 12/28/2010 | US7858312 Method of treating bladder and lower urinary tract syndromes |
| 12/28/2010 | US7858295 Methods for prolonging survival of platelets using UDP-galactose |
| 12/28/2010 | US7858128 preparing potassium calcium hydroxycitric acid from plant extract of the rind of Garcinia fruit; nutraceuticals for dietetics |
| 12/28/2010 | US7858122 tablet comprising water dispersible rate controlling polymer hydroxypropyl methylcellulose, and polyvinyl pyrrolidone; effective plasma levels over 24 hour period with diminished incidences of neuropsychiatric adverse events by eliminating the troughs and peaks of drug concentration in a patients |
| 12/28/2010 | US7858121 Tablets; reduced side effects; cancer pain; substantially less fentanyl by weight than known oral formulation |
| 12/28/2010 | US7858120 use in veterinary medicine; improve the taste of pradofloxacin Quinolone antibiotics with a flavoring mixture of proteins, fats, and carbohydrates |
| 12/28/2010 | US7858118 Useful for the post surgery pain control |
| 12/28/2010 | US7858115 Phospholipid gel compositions for drug delivery and methods of treating conditions using same |
| 12/28/2010 | US7858114 used as plaster on skin; comprises adherent layer, intermediate membrane, and drug reservoir layer sequentially from skin side, wherein drug reservoir layer comprises an antidementia drug, an aminated polymer, a polyhydric alcohol, and carboxylic acid esters |
| 12/28/2010 | US7858109 biodegradable filament having arranged thereon pressed form bodies consisting of at least one member of group of antibiotic salts such as gentamicin myristate, tobramycin palmitate; for treatment of chronic osteomyelitis |
| 12/28/2010 | US7858107 Flexible bioresorbable hemostatic packing and stent having a preselectable in-vivo residence time |
| 12/28/2010 | US7858105 reducing pigmentation of skin for cosmetic effects by administering tyrosine hydroxylase inhibitors to prevent the biosynthesis of DOPA and catecholamines; thioacetanilide; hyperpigmentation-related medical conditions such as melasma, age spots, freckles, ochronosis, and lentigo |
| 12/28/2010 | US7858102 Compositions for eliciting an immune response against Mycobacterium avium subspecies paratuberculosis |
| 12/28/2010 | US7858101 antigenic composition comprising a purified desialylated group B streptococcus (GBS) type V polysaccharide, covalently linked to a polypeptide carrier moiety that facilitates T cell-dependent antibody responses to GBS type V polysaccharide; use in treating neonatal sepsis and meningitis |
| 12/28/2010 | US7858094 Controling abberant inflamatory response; obtain animal, incubate with modulator of inflammation, monitor animal for adjustment in inflammatory response |
| 12/28/2010 | US7858085 Reducing blood glucose level in a non-obese or obese human afflicted with Type 2 diabetes by administering purified human placental alkaline phosphatase |
| 12/28/2010 | US7858080 Aldehyde conjugated flavonoid preparations |
| 12/28/2010 | US7858078 Bioabsorbable surgical composition |
| 12/28/2010 | US7858077 Functionalized phenolic esters and amides and polymers therefrom |
| 12/26/2010 | CA2707647A1 Novel 2-mercaptocyclopentanecarboxylic acid derivatives, process for their preparation and pharmaceutical compositions containing them |
| 12/23/2010 | WO2010148409A1 Compositions and methods for treating amyotrophic lateral sclerosis |
| 12/23/2010 | WO2010148396A1 Perindopril tosylate |
| 12/23/2010 | WO2010148390A2 Polyamine transport inhibitors as novel therapeutics |
| 12/23/2010 | WO2010148352A1 Time-release and micro-dose formulations for topical application of estrogen and estrogen analogs or other estrogen receptor modulators in the treatment of dry eye syndrome, and methods of preparation and application |
| 12/23/2010 | WO2010148351A1 Rhodanines and related heterocycles as kinase inhibitors |
| 12/23/2010 | WO2010148350A1 Photoproducts of tryptophan, their synthesis and uses thereof |
| 12/23/2010 | WO2010148314A2 Preparation of esomeprazole and its pharmaceutically acceptable salts |
| 12/23/2010 | WO2010148288A2 Pharmaceutical formulations with low aqueous levels of free unbound drug |
| 12/23/2010 | WO2010148268A1 Improved method for quantifying dna in a biological sample |
| 12/23/2010 | WO2010148249A1 Compositions and methods for modulation of smn2 splicing in a subject |
| 12/23/2010 | WO2010148197A1 Inhibitors of influenza viruses replication |